Abstract: Human pre-formed xenoantibodies play an important role in the hyperacute rejection response in human xenotransplantation. Disclosed are materials and methods for removing or neutralizing such antibodies. Also disclosed are materials and methods for reducing or eliminating the epitopes in the donor organs that are recognized by such antibodies. Such epitopes are formed as the result of activity by the enzyme &agr;-1,3 galactosyltransferase. The porcine gene encoding &agr;-1,3 galactosyltransferase is disclosed, as are materials and methods for inactivating (“knocking out”) the &agr;-1,3 galactosyltransferase gene in mammalian cells and embryos. Included are nucleic acid constructs useful for inactivating the &agr;-1,3 galactosyltransferase gene in a target cell. Also disclosed is a novel leukemia inhibitory factor (T-LIF) that is useful for maintenance of embryonic stem cells and primordial germ cells in culture.

Abstract: Vehicle monitoring arrangement tracks and records vehicle operation for post vehicle use supervision. In one specific embodiment, a record of vehicle-operation data contains periodic recordings of speed and direction of a vehicle while it was being driven, as such data is provided by a conventional electronic compass and the vehicle's electronic speed indicating signal. A processor performs calculations using speed and directional data to calculate acceleration and rate of directional change. Vehicle operation data from the recording devices and the calculations performed is compared to stored reference data to determine if the vehicle was abused or driven in an unsafe manner by the operator. The data is output to a display showing vehicle operating data and instances where the vehicle was abused or driven in an unsafe manner.

Abstract: A device for mounting a structure, such as a video camera, on a support includes a base and an arm projecting from the base. The video camera rests on one surface of the base and another surface rests on the support. The arm is adapted for insertion into a recessed cavity in the support, such as an antenna hole in a television set to provide a stable mounting device for the video camera. The angle of the video camera can be altered by pivoting the camera around the arm.

Abstract: Human pre-formed xenoantibodies play an important role in the hyperacute rejection response in human xenotransplantation. Disclosed are materials and methods for removing or neutralizing such antibodies. Also disclosed are materials and methods for reducing or eliminating the epitopes in the donor organs that are recognized by such antibodies. Such epitopes are formed as the result of activity by the enzyme .alpha.-1,3 galactosyltransferase. The porcine gene encoding .alpha.-1,3 galactosyltransferase is disclosed, as are materials and methods for inactivating ("knocking out") the .alpha.-1,3 galactosyltransferase gene in mammalian cells and embryos. Included are nucleic acid constructs useful for inactivating the .alpha.-1,3 galactosyltransferase gene in a target cell. Also disclosed is a novel leukemia inhibitory factor (T-LIF) that is useful for maintenance of embryonic stem cells and primordial germ cells in culture.

Abstract: A line stripping basket is used by fly casters to hold line stripped from a reel prior to being cast or upon being manually retrieved by a fly angler. The line stripping basket utilizes a waist encircling wading belt and a cooperating flexible line receiving basket that is attachable to, and detachable from the wading belt. The flexible basket has fabric or mesh sidewalls, an open mesh bottom and may carry one or more line stabilizing devices. The line stripping basket can be stowed in a belt attached pouch.

Abstract: A coin sorter for sorting mixed coins by denomination includes a rotatable disc, a drive motor for rotating the disc, and a stationary sorting head having a lower surface generally parallel to the upper surface of the rotatable disc and spaced slightly therefrom. The lower surface of the sorting head forms a plurality of exit channels for guiding coins of different denominations to different discharge stations around the periphery of the disc. A plurality of coin sensor/discriminators are mounted in the stationary sorting head over the rotatable disc for discriminating between valid and invalid coins guided by said stationary sorting head. At least one coin sensor/discriminator is mounted in each of the plurality of exit channels.

Abstract: A coin sorter for sorting mixed coins by denomination. The apparatus comprises a rotatable disc which has a resilient surface for receiving coins and imparting rotational movement to the coins. A stationary sorting head has a contoured surface spaced slightly away from and generally parallel to the resilient surface of the rotatable disc. The stationary sorting head sorts and discharges coins of different denominations at different exits around the periphery of the stationary sorting head. The sorting head includes a separate exit channel for each denomination of coin, and a sensor for each coin denomination within the exit channel for that denomination. An encoder monitors the movement of a sensed coin on the rotating disc downstream of the sensors by monitoring the angular movement of the disc. Further, a coin discriminator is used to detect foreign and counterfeit coins and to prevent the detected invalid coins from being discharged with the valid coins.

Abstract: A coin sorter for sorting mixed coins by denomination. The apparatus comprises a rotatable disc which has a resilient surface for receiving coins and imparting rotational movement to the coins. A stationary sorting head has a contoured surface spaced slightly away from and generally parallel to the resilient surface of the rotatable disc. The stationary sorting head sorts and discharges coins of different denominations at different exits around the periphery of the stationary sorting head. The sorting head includes a separate exit channel for each denomination of coin, and a sensor for each coin denomination within the exit channel for that denomination. An encoder monitors the movement of a sensed coin on the rotating disc downstream of the sensors by monitoring the angular movement of the disc. Further, a coin discriminator is used to detect foreign and counterfeit coins and to prevent the detected invalid coins from being discharged with the valid coins.

Abstract: A rotational moulding apparatus includes a device (5) disposed inside the mould for measuring temperature. A processor (6) forming part of a feedback tool (7) enables real time monitoring and control of the moulding process. Identifiable points on the temperature time moulding characteristic are employed to control the operation of the apparatus to optimise the properties of the mouldings obtained.

Abstract: DNA sequence of S-genes which encode S-proteins and control the self-incompatibility reaction in gametophytic self-incompatible plants have been identified. The DNA sequence encoding several S-proteins of N. alata and their attendant signal sequences are specifically provided. Regulatory sequences which direct expression of the S-genes in reproduction tissue of self-incompatible plants have also been identified. A method for the identification and isolation of cDNA and genomic DNA coding sequences of the S-genes is described.

Abstract: A telephone system employs a novel message system for calling parties. The switch controller includes selectable and programmable announcement machines, while the telephone devices include indicators which allow call transferees the ability to determine the reason the call was transferred, e.g., the called telephone was busy, did not answer or the called telephone party is in conference. When desired, a telephone party is capable of programming the switch controller to reply to any particular incoming phone calls with one of a number of customized or preselected messages.

Abstract: Disclosed are two arrangements for remotely indicating the status of a washing machine and/or a dryer. In one arrangement, a current sense circuit is employed along with an optional vibration sense circuit to detect whether or not the washing machine or the dryer are on or off. At a change from on-to-off or from off-to-on, the status of the washing machine or dryer is transmitted over the air to a receiver for status display to the operator. In the second arrangement, detection of the status is internal to the washing machine and the dryer and the status includes additional information such as the type of cycle and the amount of time left before the cycle finishes. To avoid constant transmission of such information, the receiver includes a timer which is synchronized to the washing machine/dryer timing circuits.

Abstract: There is provided a new and useful slip lock forming apparatus comprising a support structure, a forming die mounted on the support structure, a clamping mechanism mounted on the support structure and comprising a pair of clamping members movable between an open and a closed position for holding a workpiece in position relative to the die, a press mechanism mounted on the structure and comprising a pair of pressing surfaces at least one of which is movable relative to the other between a first position in which the surfaces are in contact and a second position in which the surfaces are spaced from each other, and a forming bar mounted on the structure and movable between a retracted position and an extended position for forming a workpiece around the die.

Abstract: A circuit arrangement for filtering input signals carried on PCM channels. The circuit arrangement includes a plurality of digital signal processors arranged in a parallel manner each having a set of filtering operations, a multiplexer for distributing the input signals to each digital signal processor, a processor for analyzing frequency characteristics output by the digital signal processors and an addressing PROM for controlling a correspondence between the PCM channels and the filtering operations in each of the digital signal processors.

Abstract: A process for synthesizing alpha-substituted O,O-dialkyl dithiophosphato amides, comprising the step of contacting a C.sub.8 -C.sub.22 alpha-chloro amide with an aqueous solution of a salt of an O,O-dialkyl dithiophosphoric acid, at a temperature above the melting point of the alpha-chloro amide and in the range of from about 100.degree. C. to about 200.degree. C., is disclosed.

Abstract: Alpha-sulfoxide and alpha-sulfone carboxyl compounds useful as detergent surfactants are disclosed. The compounds are particularly effective in removing greasy/oily soils under cold water laundering conditions. Detergent compositions containing the compounds are preferably contain cosurfactants and builder materials.