Abstract: Provided herein are methods of separating molecular species of a guanine-rich oligonucleotide from a mixture of molecular species, wherein at least one molecular species of the mixture is a quadruplex formed from the guanine-rich oligonucleotide. In exemplary embodiments, the methods comprise (a) applying the mixture to a chromatographic matrix comprising a hydrophobic ligand, wherein said hydrophobic ligand comprises C4 to C8 alkyl chains, wherein molecular species bind to the hydrophobic ligand and (b) applying a mobile phase which comprises a gradient of acetate and a gradient of acetonitrile but no cationic ion pairing agent to the chromatographic matrix to elute molecular species of the guanine-rich oligonucleotide. In exemplary aspects, the guamne-rich oligonucleotide elutes in a first set of elution fractions and a quadruplex formed from the guanine-rich oligonucleotide elutes in a second set of elution fractions.

Abstract: Provided herein are methods of determining product quality of an antibody composition, wherein the ADCC activity level of the antibody composition is a criterion upon which product quality of the antibody composition is based. In exemplary embodiments, the method comprises (i) determining the total afucosylated (TAF) glycan content of a sample of an antibody composition; and (ii) determining the product quality as acceptable and/or achieving the ADCC activity level criterion when the TAF glycan content determined in (i) is within a target range. Related methods of monitoring product quality and methods of producing an antibody composition are further provided herein.

Abstract: The intense purple dye normally found in purple primers for use in the adhesive bonding of plastics is replaced with a leuco dye capable developing a visually intense color when activated through contact with the particular plastic being bonded or a complementary solvent cement.

Abstract: The intense purple dye normally found in purple primers for use in the adhesive bonding of plastics is replaced with a leuco dye capable developing a visually intense color when activated through contact with the particular plastic being bonded or a complementary solvent cement.

Abstract: The intense purple dye normally found in purple primers for use in the adhesive bonding of plastics is replaced with a leuco dye capable developing a visually intense color when activated through contact with the particular plastic being bonded or a complementary solvent cement.

Abstract: The intense purple dye normally found in purple primers for use in the adhesive bonding of plastics is replaced with a leuco dye capable developing a visually intense color when activated through contact with the particular plastic being bonded or a complementary solvent cement.

Abstract: Macrocyclic compounds, e.g., ketones, crown ethers, methicones etc., have been found to be effective co-solvents in solvent based adhesives for pipe joining applications. Because of their enhanced solubility with VOC exempt solvents (40 C.F.R. 51.100), the calculated VOC content of the adhesive can be lowered to at least 75% of those established by SCAQMD Rule 116A.

Abstract: Macrocyclic compounds, e.g., ketones, crown ethers, methicones etc., have been found to be effective co-solvents in solvent based adhesives for pipe joining applications. Because of their enhanced solubility with VOC exempt solvents (40 C.F.R. 51.100), the calculated VOC content of the adhesive can be lowered to at least 75% of those established by SCAQMD Rule 116A.

Abstract: Oligomers of polycyclic olefin monomers, and optionally allylic or olefinic monomers, and a method of making such oligomers that includes reacting polycyclic olefin monomers in the presence of a Ni or Pd containing catalyst, or in the case of allylic monomers in the presence of a free radical initiator. The oligomers can be included in photoresist compositions as dissolution rate modifiers. The photoresist compositions can further include a polymeric binder resin, a photoacid generator, and solvents.

Abstract: Oligomers of polycyclic olefin monomers, and optionally allylic or olefinic monomers, and a method of making such oligomers that includes reacting polycyclic olefin monomers in the presence of a Ni or Pd containing catalyst, or in the case of allylic monomers in the presence of a free radical initiator. The oligomers can be included in photoresist compositions as dissolution rate modifiers. The photoresist compositions can further include a polymeric binder resin, a photoacid generator, and solvents.

Abstract: A method of bonding two substrates at least one of which is a rubbery polymeric material having carbon-carbon double bonds on the polymer backbone, the method comprising: a) applying an aqueous polyurethane dispersion adhesive composition to at least one of the substrates, the adhesive compostion further comprising an epoxy resin; b) allowing the composition to dry; and then c) joining the substrates with heating to activate the adhesive. The substrates are suitably footwear materials such as a molded rubber outer sole which has been first primed with a chlorinating primer, and a foam midsole of a material such as a lightly crosslinked ethylene vinyl acetate. The process results in bonded assemblies having improved humidity resistance.