Patents by Inventor Robert J. Johnston

Robert J. Johnston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240166741
    Abstract: The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.
    Type: Application
    Filed: June 14, 2023
    Publication date: May 23, 2024
    Inventors: Jane Grogan, Robert J. Johnston, Bryan Irving, Jason Hackney, Xin Yu, Dan Eaton, Kristin Bowles, Laetitia Comps-Agrar
  • Publication number: 20240131037
    Abstract: Methods and compositions for using a tetracycline compound to treat bacterial infections are described. In one embodiment, for example, the invention provides a method of treating a subject for an infection, comprising administering to said subject an effective amount of 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof, such that said subject is treated, wherein said infection is selected from the group consisting of MSSA, MRSA, B-streptococci, Viridans streptococci, Enterococcus, or combinations thereof.
    Type: Application
    Filed: August 27, 2023
    Publication date: April 25, 2024
    Inventors: Sean M. Johnston, Robert D. Arbeit, Thomas J. Bigger, Dennis P. Molnar, S. Ken Tanaka
  • Publication number: 20240117037
    Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
    Type: Application
    Filed: June 30, 2023
    Publication date: April 11, 2024
    Inventors: Jane L. GROGAN, Robert J. JOHNSTON, Yan WU, Wei-Ching LIANG, Patrick LUPARDUS, Mahesh YADAV, Dhaya SESHASAYEE, Meredith HAZEN
  • Publication number: 20240092907
    Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.
    Type: Application
    Filed: February 1, 2023
    Publication date: March 21, 2024
    Applicants: Five Prime Therapeutics, Inc., Bristol-Myers Squibb Company
    Inventors: Robert J. Johnston, Arvind Rajpal, Paul O. Sheppard, Luis Borges, Andrew Rankin, Keith Sadoon Bahjat, Alan J. Korman, Andy X. Deng, Lin Hui Su, Ginger Rakestraw
  • Publication number: 20230386417
    Abstract: Often when there is a glare on a display screen the user may be able to mitigate the glare by tilting or otherwise moving the screen or changing their viewing position. However, when driving a car there are limited options for overcoming glares on the dashboard, especially when you are driving for a long distance in the same direction. Embodiments are directed to eliminating such glare. Other embodiments are related to mixed reality (MR) and filling in occluded areas.
    Type: Application
    Filed: May 24, 2023
    Publication date: November 30, 2023
    Applicant: Intel Corporation
    Inventors: Arthur J. Runyan, Richmond Hicks, Nausheen Ansari, Narayan Biswal, Ya-Ti Peng, Abhishek R. Appu, Wen-Fu Kao, Sang-Hee Lee, Joydeep Ray, Changliang Wang, Satyanarayana Avadhanam, Scott Janus, Gary Smith, Nilesh V. Shah, Keith W. Rowe, Robert J. Johnston
  • Publication number: 20230279102
    Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
    Type: Application
    Filed: December 7, 2022
    Publication date: September 7, 2023
    Inventors: Jane L. GROGAN, Robert J. JOHNSTON, Yan WU, Wei-Ching LIANG, Patrick LUPARDUS, Mahesh YADAV, Dhaya SESHASAYEE, Meredith HAZEN
  • Patent number: 11699404
    Abstract: Often when there is a glare on a display screen the user may be able to mitigate the glare by tilting or otherwise moving the screen or changing their viewing position. However, when driving a car there are limited options for overcoming glares on the dashboard, especially when you are driving for a long distance in the same direction. Embodiments are directed to eliminating such glare. Other embodiments are related to mixed reality (MR) and filling in occluded areas.
    Type: Grant
    Filed: March 24, 2022
    Date of Patent: July 11, 2023
    Assignee: Intel Corporation
    Inventors: Arthur J. Runyan, Richmond Hicks, Nausheen Ansari, Narayan Biswal, Ya-Ti Peng, Abhishek R. Appu, Wen-Fu Kao, Sang-Hee Lee, Joydeep Ray, Changliang Wang, Satyanarayana Avadhanam, Scott Janus, Gary Smith, Nilesh V. Shah, Keith W. Rowe, Robert J. Johnston
  • Patent number: 11603406
    Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: March 14, 2023
    Assignees: Five Prime Therapeutics, Inc., Bristol-Myers Squibb Company
    Inventors: Robert J. Johnston, Arvind Rajpal, Paul O. Sheppard, Luis Borges, Andrew Rankin, Keith Sadoon Bahjat, Alan J. Korman, Andy X. Deng, Lin Hui Su, Ginger Rakestraw
  • Patent number: 11551389
    Abstract: Systems, apparatuses and methods may a performance-enhanced computing system comprising a sensor for measuring luminance values corresponding to light focused onto the sensor at a plurality of pixel locations, a memory including a set of instructions, and a processor. The processor executes a set of instructions causing the system to generate a multi-segment tone mapping curve, generate a set of tone mapping values corresponding to the multi-segment tone mapping curve for equally spaced input values between zero and one for storage into a look up table, and process the luminance values using the look up table to apply the tone mapping curve to the luminance values of the pixels.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: January 10, 2023
    Assignee: Intel Corporation
    Inventors: Stanley J. Baran, Abhishek R. Appu, Sang-Hee Lee, Atthar H. Mohammed, Jong Dae Oh, Hiu-Fai R. Chan, Joydeep Ray, Kunjal Parikh, Changliang Wang, Srikanth Kambhatla, Gary Smith, Satyanarayana Avadhanam, Richmond Hicks, Robert J. Johnston, Narayan Biswal, Susanta Bhattacharjee
  • Publication number: 20220298258
    Abstract: Methods of identifying and using PSGL-1 antagonists are provided. Such methods include, but are not limited to, methods of treating cancer. PSGL-1 antagonists include, but are not limited to, antibodies that bind PSGL-1 and antibodies that bind VISTA, wherein the antibodies inhibit PSGL-1 binding to VISTA, e.g., at acidic pH (e.g., pH 6.0), as well as PSGL-1 and VISTA extracellular domain polypeptides.
    Type: Application
    Filed: March 15, 2022
    Publication date: September 22, 2022
    Applicants: Bristol-Myers Squibb Company, Five Prime Therapeutics, Inc.
    Inventors: Robert J. Johnston, Andrew Rankin, Arathi Krishnakumar, Paul O. Sheppard, Arvind Rajpal
  • Publication number: 20220284867
    Abstract: Often when there is a glare on a display screen the user may be able to mitigate the glare by tilting or otherwise moving the screen or changing their viewing position. However, when driving a car there are limited options for overcoming glares on the dashboard, especially when you are driving for a long distance in the same direction. Embodiments are directed to eliminating such glare. Other embodiments are related to mixed reality (MR) and filling in occluded areas.
    Type: Application
    Filed: March 24, 2022
    Publication date: September 8, 2022
    Inventors: Arthur J. Runyan, Richmond Hicks, Nausheen Ansari, Narayan Biswal, Ya-Ti Peng, Abhishek R. Appu, Wen-Fu Kao, Sang-Hee Lee, Joydeep Ray, Changliang Wang, Satyanarayana Avadhanam, Scott Janus, Gary Smith, Nilesh V. Shah, Keith W. Rowe, Robert J. Johnston
  • Patent number: 11435819
    Abstract: Systems, apparatuses and methods may provide for technology to improve user experience when viewing simulated 3D objects on a display. Head and upper-body movements may be tracked and recognized as gestures to alter the displayed viewing angle. The technology provides for a very natural way to look around, under, or over objects.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: September 6, 2022
    Assignee: Intel Corporation
    Inventors: Robert J. Johnston, Satyanarayana Avadhanam, Changliang Wang, Narayan Biswal, Archie Sharma, Richmond Hicks, Joydeep Ray, Abhishek R. Appu, Stanley J. Baran, Sang-Hee Lee, Atthar H. Mohammed, Jong Dae Oh, Hiu-Fai Chan, Sumit Mohan, Jill M. Boyce, Yi-Jen Chiu
  • Patent number: 11322099
    Abstract: Often when there is a glare on a display screen the user may be able to mitigate the glare by tilting or otherwise moving the screen or changing their viewing position. However, when driving a car there are limited options for overcoming glares on the dashboard, especially when you are driving for a long distance in the same direction. Embodiments are directed to eliminating such glare. Other embodiments are related to mixed reality (MR) and filling in occluded areas.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: May 3, 2022
    Assignee: Intel Corporation
    Inventors: Arthur J. Runyan, Richmond Hicks, Nausheen Ansari, Narayan Biswal, Ya-Ti Peng, Abhishek R. Appu, Wen-Fu Kao, Sang-Hee Lee, Joydeep Ray, Changliang Wang, Satyanarayana Avadhanam, Scott Janus, Gary Smith, Nilesh V. Shah, Keith W. Rowe, Robert J. Johnston
  • Patent number: 11306150
    Abstract: Methods of identifying and using PSGL-1 antagonists are provided. Such methods include, but are not limited to, methods of treating cancer. PSGL-1 antagonists include, but are not limited to, antibodies that bind PSGL-1 and antibodies that bind VISTA, wherein the antibodies inhibit PSGL-1 binding to VISTA, e.g., at acidic pH (e.g., pH 6.0), as well as PSGL-1 and VISTA extracellular domain polypeptides.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: April 19, 2022
    Assignees: Bristol-Myers Squibb Company, Five Prime Therapeutics, Inc.
    Inventors: Robert J. Johnston, Andrew Rankin, Arathi Krishnakumar, Paul O. Sheppard, Arvind Rajpal
  • Patent number: 11289030
    Abstract: Often when there is a glare on a display screen the user may be able to mitigate the glare by tilting or otherwise moving the screen or changing their viewing position. However, when driving a car there are limited options for overcoming glares on the dashboard, especially when you are driving for a long distance in the same direction. Embodiments are directed to eliminating such glare. Other embodiments are related to mixed reality (MR) and filling in occluded areas.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: March 29, 2022
    Assignee: Intel Corporation
    Inventors: Arthur J. Runyan, Richmond Hicks, Nausheen Ansari, Narayan Biswal, Ya-Ti Peng, Abhishek R. Appu, Wen-Fu Kao, Sang-Hee Lee, Joydeep Ray, Changliang Wang, Satyanarayana Avadhanam, Scott Janus, Gary Smith, Nilesh V. Shah, Keith W. Rowe, Robert J. Johnston
  • Publication number: 20220073617
    Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.
    Type: Application
    Filed: July 10, 2019
    Publication date: March 10, 2022
    Applicants: Five Prime Therapeutics, Inc., Bristol-Myers Squibb Company
    Inventors: Robert J. Johnston, Arvind Rajpal, Paul O. Sheppard, Luis Borges, Andrew Rankin, Keith Sadoon Bahjat, Alan J. Korman, Xiaodi Deng, Lin Hui Su, Ginger Rakestraw, Jason R. Pinckney, David A. Critton, Guodong Chen, Richard Y. Huang, Ekaterina G. Deyanova, Michael Quigley, Hadia Lemar, Akbar Nayeem
  • Publication number: 20220064286
    Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
    Type: Application
    Filed: November 15, 2021
    Publication date: March 3, 2022
    Inventors: Jane L. GROGAN, Robert J. JOHNSTON, Yan WU, Wei-Ching LIANG, Patrick LUPARDUS, Mahesh YADAV, Dhaya SESHASAYEE, Meredith HAZEN
  • Publication number: 20210349527
    Abstract: Systems, apparatuses and methods may provide for technology to improve user experience when viewing simulated 3D objects on a display. Head and upper-body movements may be tracked and recognized as gestures to alter the displayed viewing angle. The technology provides for a very natural way to look around, under, or over objects.
    Type: Application
    Filed: January 28, 2021
    Publication date: November 11, 2021
    Inventors: Robert J. Johnston, Satyanarayana Avadhanam, Changliang Wang, Narayan Biswal, Archie Sharma, Richmond Hicks, Joydeep Ray, Abhishek R. Appu, Stanley J. Baran, Sang-Hee Lee, Atthar H. Mohammed, Jong Dae Oh, Hiu-Fai Chan, Sumit Mohan, Jill M. Boyce, Yi-Jen Chiu
  • Publication number: 20210340253
    Abstract: The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.
    Type: Application
    Filed: July 2, 2021
    Publication date: November 4, 2021
    Inventors: Jane Grogan, Robert J. Johnston, Bryan Irving, Jason Hackney, Xin Yu, Dan Eaton, Kristin Bowles, Laetitia Comps-Agrar
  • Publication number: 20210332132
    Abstract: The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.
    Type: Application
    Filed: July 2, 2021
    Publication date: October 28, 2021
    Inventors: Jane Grogan, Robert J. Johnston, Bryan Irving, Jason Hackney, Xin Yu, Dan Eaton, Kristin Bowles, Laetitia Comps-Agrar