Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: A method and apparatus for use in improving the linearity characteristics of MOSFET devices using an accumulated charge sink (ACS) are disclosed. The method and apparatus are adapted to remove, reduce, or otherwise control accumulated charge in SOI MOSFETs, thereby yielding improvements in FET performance characteristics. In one exemplary embodiment, a circuit having at least one SOI MOSFET is configured to operate in an accumulated charge regime. An accumulated charge sink, operatively coupled to the body of the SOI MOSFET, eliminates, removes or otherwise controls accumulated charge when the FET is operated in the accumulated charge regime, thereby reducing the nonlinearity of the parasitic off-state source-to-drain capacitance of the SOI MOSFET. In RF switch circuits implemented with the improved SOI MOSFET devices, harmonic and intermodulation distortion is reduced by removing or otherwise controlling the accumulated charge when the SOI MOSFET operates in an accumulated charge regime.

Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.

Abstract: Embodiments disclosed herein are directed to a self-learning bladder volume monitoring system. The system can include a bladder volume (BV) system configured to measure an electrical impedance of a bladder region of a patient and determine a volume of fluid disposed therein using an impedance to bladder volume model (“By model”). Further, the system can measure a total body water (“TBW”) for the patient and modify the BV model to account for variations in TBW within the tissues surrounding the bladder providing a more accurate bladder volume measurement. The system can include a “training unit” which can include one of a user input interface, an automatic urine output monitoring system, an ultrasound system, and an intrabladder pressure system configured to verify a volume of fluid within or voided from the bladder and train the BV model.

Abstract: A method is disclosed for forking call audio channels. The method includes, during an active call, receiving a first audio stream of first call audio that originates from a far-end telephony device, and receiving a second audio stream of second call audio that originates from a microphone of a near-end headset. Further, the method includes generating, during the active call, a third audio stream containing the first call audio by processing the first audio stream, and generating a fourth audio stream containing the second call audio by processing the second audio stream. Still yet, the method includes, during the active call, generating a fifth audio stream containing the first call audio, and generating a sixth audio stream containing the second call audio.

Abstract: A method is disclosed for forking call audio channels. The method includes, during an active call, receiving a first audio stream of first call audio that originates from a far-end telephony device, and receiving a second audio stream of second call audio that originates from a microphone of a near-end headset. Further, the method includes generating, during the active call, a third audio stream containing the first call audio by processing the first audio stream, and generating a fourth audio stream containing the second call audio by processing the second audio stream. Still yet, the method includes, during the active call, generating a fifth audio stream containing the first call audio, and generating a sixth audio stream containing the second call audio.

Abstract: A method is disclosed for forking call audio channels. The method includes, during an active call, receiving a first audio stream of first call audio that originates from a far-end telephony device, and receiving a second audio stream of second call audio that originates from a microphone of a near-end headset. Further, the method includes generating, during the active call, a third audio stream containing the first call audio by processing the first audio stream, and generating a fourth audio stream containing the second call audio by processing the second audio stream. Still yet, the method includes, during the active call, generating a fifth audio stream containing the first call audio, and generating a sixth audio stream containing the second call audio. In addition, the method includes, during the active call, concurrently transmitting: the third audio stream, the fourth audio stream, the fifth audio stream, and the sixth audio stream.

Abstract: A portable construction tent is provided. The portable construction tent is especially suitable for use in inclement weather conditions. In particular, the portable construction tent is especially suitable for use on a building when construction or repair is being done to the roof of the building. The portable tent unfolds, is adjusted for size, and then is secured to the parapet walls of the roof and finally is locked into place. A discard-able, recycle-able wrap is draped over support poles of the tent and is secured. In an embodiment, the wrap may be a low-density polyethylene film or cellophane. Further, in an embodiment, the wrap may be heat shrunk around the poles (which may be steel rafters), which are bolted to the parapet walls. Once in place, the portable construction tent allows workers to work on the roof of a building in almost any weather condition.

Abstract: A method is disclosed for forking call audio channels. The method includes, during an active call, receiving a first audio stream of first call audio that originates from a far-end telephony device, and receiving a second audio stream of second call audio that originates from a microphone of a near-end headset. Further, the method includes generating, during the active call, a third audio stream containing the first call audio by processing the first audio stream, and generating a fourth audio stream containing the second call audio by processing the second audio stream. Still yet, the method includes, during the active call, generating a fifth audio stream containing the first call audio, and generating a sixth audio stream containing the second call audio. In addition, the method includes, during the active call, concurrently transmitting: the third audio stream, the fourth audio stream, the fifth audio stream, and the sixth audio stream.

Abstract: A method is disclosed for forking call audio channels. The method includes, during an active call, receiving a first audio stream of first call audio that originates from a far-end telephony device, and receiving a second audio stream of second call audio that originates from a microphone of a near-end headset. Further, the method includes generating, during the active call, a third audio stream containing the first call audio by processing the first audio stream, and generating a fourth audio stream containing the second call audio by processing the second audio stream. Still yet, the method includes, during the active call, generating a fifth audio stream containing the first call audio, and generating a sixth audio stream containing the second call audio. In addition, the method includes, during the active call, concurrently transmitting: the third audio stream, the fourth audio stream, the fifth audio stream, and the sixth audio stream.

Abstract: Headsets having corresponding audio adapters and methods comprise: a microphone configured to generate analog audio for a voice call; an analog-to-digital converter configured to convert the analog audio to digital audio; a voice activity detector configured to detect speech in the digital audio; a processor configured to i) determine a temporal characteristic of the speech, and ii) generate a message based on the temporal characteristic of the speech and a temporal characteristic of the voice call; and a transmitter configured to transmit the message.

Abstract: A method is disclosed for forking call audio channels. The method includes, during an active call, receiving a first audio stream of first call audio that originates from a far-end telephony device, and receiving a second audio stream of second call audio that originates from a microphone of a near-end headset. Further, the method includes generating, during the active call, a third audio stream containing the first call audio by processing the first audio stream, and generating a fourth audio stream containing the second call audio by processing the second audio stream. Still yet, the method includes, during the active call, generating a fifth audio stream containing the first call audio, and generating a sixth audio stream containing the second call audio. In addition, the method includes, during the active call, concurrently transmitting: the third audio stream, the fourth audio stream, the fifth audio stream, and the sixth audio stream.

Abstract: Headsets having corresponding audio adapters and methods comprise: a microphone configured to generate analog audio for a voice call; an analog-to-digital converter configured to convert the analog audio to digital audio; a voice activity detector configured to detect speech in the digital audio; a processor configured to i) determine a temporal characteristic of the speech, and ii) generate a message based on the temporal characteristic of the speech and a temporal characteristic of the voice call; and a transmitter configured to transmit the message.

Abstract: A portable construction tent is provided. The portable construction tent is especially suitable for use in inclement weather conditions. In particular, the portable construction tent is especially suitable for use on a building when construction or repair is being done to the roof of the building. The portable tent unfolds, is adjusted for size, and then is secured to the parapet walls of the roof and finally is locked into place. A discard-able, recycle-able wrap is draped over support poles of the tent and is secured. In an embodiment, the wrap may be a low-density polyethylene film or cellophane. Further, in an embodiment, the wrap may be heat shrunk around the poles (which may be steel rafters), which are bolted to the parapet walls. Once in place, the portable construction tent allows workers to work on the roof of a building in almost any weather condition.

Abstract: Headsets having corresponding audio adapters and methods comprise: a microphone configured to generate analog audio for a voice call; an analog-to-digital converter configured to convert the analog audio to digital audio; a voice activity detector configured to detect speech in the digital audio; a processor configured to i) determine a temporal characteristic of the speech, and ii) generate a message based on the temporal characteristic of the speech and a temporal characteristic of the voice call; and a transmitter configured to transmit the message.

Abstract: A construction system for releasing moisture from a building is provided. The system is especially suitable for use in buildings having a hip, valley or gable roof. More specifically, the device gives the hip, valley or gable roof adequate ventilation and moisture vapor release portals so as to allow air and water vapor to properly rise through the interior of the hip, valley or gable roof and out through ridge vents without becoming trapped by rafters of the hip, valley or gable roof. The system has a first unit and a second unit, wherein the first unit allows air and water vapor to pass through passageways of the first unit up through the underside of the hip, valley or gable roof up and out through the ridge vent(s) and the second unit allows air from the exterior to pass into the roof cavity to circulate through the roof cavity and into the first unit.

Abstract: Methods and apparatuses for asset management are disclosed. In one example, a system and method includes receiving an indication of a coupling of an asset to a computing device. An asset identifier stored on the asset is received and an asset data record corresponding to the asset is located. A data associated with the asset is recorded in the asset data record.

Abstract: A construction system for releasing moisture from a building is provided. The system is especially suitable for use in buildings having a hip, valley or gable roof. More specifically, the device gives the hip, valley or gable roof adequate ventilation and moisture vapor release portals so as to allow air and water vapor to properly rise through the interior of the hip, valley or gable roof and out through ridge vents without becoming trapped by rafters of the hip, valley or gable roof. The system has a first unit and a second unit, wherein the first unit allows air and water vapor to pass through passageways of the first unit up through the underside of the hip, valley or gable roof up and out through the ridge vent(s) and the second unit allows air from the exterior to pass into the roof cavity to circulate through the roof cavity and into the first unit.

Abstract: A construction system for releasing moisture from a building is provided. The system is especially suitable for use in buildings having a hip, valley or gable roof. More specifically, the device gives the hip, valley or gable roof adequate ventilation and moisture vapor release portals so as to allow air and water vapor to properly rise through the interior of the hip, valley or gable roof and out through ridge vents without becoming trapped by rafters of the hip, valley or gable roof. The system has a first unit and a second unit, wherein the first unit allows air and water vapor to pass through passageways of the first unit up through the underside of the hip, valley or gable roof up and out through the ridge vent(s) and the second unit allows air from the exterior to pass into the roof cavity to circulate through the roof cavity and into the first unit.