Abstract: An orthopaedic surgical instrument includes a patella trial and drill guide that may be used to both perform a surgical trial of the patellofemoral joint and guide the surgeon in drilling a number of anchor holes in the patella of the patient.

Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.

Abstract: In a sensor device, a plurality of light guides having a respective first end and a respective second end are arranged on a common carrier, with the first end of each light guide of the plurality of light guides at a respective defined position on the carrier. At each of the second ends of the light guides there is provided at least one sensor element which exhibits an optical behavior dependent on an analyte. The second ends are at defined perpendicular distances to the carrier. At least two of the second ends differ with respect to the defined perpendicular distances.

Abstract: A method and measurement system for calibrated measurement of at least one variable of a sample are based on an optical behaviour of at least one sensor substance which depends on the at least one variable. The at least one sensor substance is brought into contact with the sample. At least one calibration area, associated with the at least one sensor substance, is defined. At least one image is recorded which captures at least one of the at least one sensor substance and at least one of the at least one calibration area. The value of the at least one variable of the sample is derived from the at least one image, based on image data associated with the at least one of the at least one sensor substance and on image data associated with the at least one of the at least one calibration area.

Abstract: A system for analysis of a fluid sample has a carrier with a channel. A plug with a sensor can be inserted into a socket arranged on the carrier in such a way that the sensor is in contact with an interior volume of the channel. The sensor can be an optical sensor, in particular based on fluorescence. Optical fibres may be connected to the plug. A camera (8) may be provided to record an image of the plug. The carrier may in particular be a microfluidic chip and the channel a microfluidic channel.

Abstract: In a sensor device, a plurality of light guides having a respective first end and a respective second end are arranged on a common carrier, with the first end of each light guide of the plurality of light guides at a respective defined position on the carrier. At each of the second ends of the light guides there is provided at least one sensor element which exhibits an optical behavior dependent on an analyte. The second ends are at defined perpendicular distances to the carrier. At least two of the second ends differ with respect to the defined perpendicular distances.

Abstract: A method and measurement system for calibrated measurement of at least one variable of a sample are based on an optical behaviour of at least one sensor substance which depends on the at least one variable. The at least one sensor substance is brought into contact with the sample. At least one calibration area, associated with the at least one sensor substance, is defined. At least one image is recorded which captures at least one of the at least one sensor substance and at least one of the at least one calibration area. The value of the at least one variable of the sample is derived from the at least one image, based on image data associated with the at least one of the at least one sensor substance and on image data associated with the at least one of the at least one calibration area.