Abstract: Emulsion-based and micromolded (“MM”) or three dimensional printed (“3DP”) polymeric formulations for single injection of antigen, preferably releasing at two or more time periods, have been developed. Formulations are preferably formed of biocompatible, biodegradable polymers. Discrete regions encapsulating antigen, alone or in combination with other antigens, adjuvants, stabilizers, and release modifiers, are present in the formulations. Antigen is preferably present in excipient at the time of administration, or on the surface of the formulation, for immediate release, and incorporated within the formulation for release at ten to 45 days after initial release of antigen, optionally at ten to 90 day intervals for release of antigen in one or more additional time periods. Antigen may be stabilized through the use of stabilizing agents such as trehalose glass. In a preferred embodiment for immunization against polio, antigen is released at the time of administration, and two, four and six months thereafter.

Abstract: An electric-motor-powered centrifugal fuel pump including a vacuum control device to achieve the initial priming of the centrifugal pump. The electric motor which drives a centrifugal impeller is housed within the pump itself and, as such, is immersed in the fuel being pumped. An associated filter bowl incorporates a float valve, thus becoming a filter and float bowl which controls the vacuum so that when the fuel level reaches a predetermined point, the float valve rises and engages its valve seat, thus shutting off the vacuum source. A secondary ball valve is also provided in the vacuum line so that, in the event of the vehicle's overturning, this ball valve will close the vacuum line and prevent gravitational fuel flow to the vacuum source. When the vacuum draws sufficient fuel into the centrifugal pump cavity, the centrifugal impeller is then capable of discharging this fuel under pressure through the filter to an outlet port that is connected to the carburetor.