Abstract: Disclosed are methods for providing substituted sulfonamide analogs of memantine and amantadine. Also disclosed are compositions for treating glioblastoma multiforme cancer cells. The compositions may include a sulfonamide analog(s) of memantine having an aromatic or heteroaromatic substituent or a sulfonamide analog(s) of amantadine having an aromatic or heteroaromatic substituent and an optional metabolic inhibitor. Also disclosed are methods and compositions for treating an organism diagnosed with a brain cancer of the type of glioblastoma multiforme cancer.

Abstract: Disclosed is a method for preparing patient derived cancer cells in a patient derived serum and/or plasma and individualized cancer cell support media containing amino acids, vitamins, inorganic salts and glucose in concentrations corresponding to the organ in which the cancer appears. Also disclosed is a method for screening compounds to determine the effectiveness of those compounds in treating the patient's specific cancer.

Abstract: Provided herein are compositions and methods for the treatment or prevention of viral infections via the use of chemical substances administered in a combinatory fashion for the suppression, inhibition, and elimination of viral loads. These compositions and methods use a glycolysis inhibitor (e.g., 2-deoxy-D-glucose (2-DG)) in combination with one or more compounds comprising one or more aromatic rings and at least one alkylamino(C?12) group or substituted alkylamino(C?12) group.