Patents by Inventor Robert J. Sims, III

Robert J. Sims, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSION PROTEINS AND METHODS FOR IDENTIFYING BROMODOMAIN INHIBITING COMPOUNDS
    Publication number: 20190048048
    Abstract: The present invention relates methods for identifying bromodomain inhibiting compounds.
    Type: Application
    Filed: June 27, 2018
    Publication date: February 14, 2019
    Applicant: CONSTELLATION PHARMACEUTICALS, INC.
    Inventors: Hon-Ren Huang, Robert J. Sims, III, Steven Frank Bellon
  • USE OF CBP/EP300 AND BET INHIBITORS FOR TREATMENT OF CANCER
    Publication number: 20170196878
    Abstract: The present invention relates to the use of CBP/EP300 inhibitors and BET inhibitors for the treatment of cancer. In some embodiments, the use is to treat cancer that is resistant to BET inhibitors.
    Type: Application
    Filed: March 20, 2017
    Publication date: July 13, 2017
    Applicants: GENENTECH, INC., CONSTELLATION PHARMACEUTICALS, INC.
    Inventors: Richard C. Centore, Andrew R. Conery, Karen Gascoigne, Robert J. Sims, III
  • TREATING TH2-MEDIATED DISEASES BY INHIBITION OF BROMODOMAINS
    Publication number: 20160024504
    Abstract: The invention provides methods for treating Th2 cytokine-mediated diseases by inhibiting bromodomain function.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Applicants: CONSTELLATION PHARMACEUTICALS, INC., GENENTECH, INC.
    Inventors: Brian K. Albrecht, Alexandre Cote, Terry Crawford, Benjamin Fauber, Hon-Ren Huang, Jose M. Lora, Steven Magnuson, Christopher G. Nasveschuk, Andres Salmeron, Robert J. Sims, III, Alexander M. Taylor
  • FUSION PROTEINS AND METHODS FOR IDENTIFYING BROMODOMAIN INHIBITING COMPOUNDS
    Publication number: 20160002306
    Abstract: The present invention relates to fusion proteins comprising at least one chromatin binding module and at least one reporter module, wherein a plurality of fusion proteins are capable of forming foci, and associated methods for identifying bromodomain inhibiting compounds.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 7, 2016
    Applicant: CONSTELLATION PHARMACEUTICALS, INC.
    Inventors: Hon-Ren Huang, Robert J. Sims, III, Steven Frank Bellon