Patents by Inventor Robert J. Watson

Robert J. Watson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-OXO-1,2-DIHYDROPYRIDINE-3,5-DICARBOXAMIDE COMPOUNDS AS BROMODOMAIN INHIBITORS
    Publication number: 20180280368
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: October 3, 2016
    Publication date: October 4, 2018
    Inventors: Stephen John ATKINSON, Emmanuel Hubert DEMONT, Lee Andrew HARRISON, Thomas George Christopher HAYHOW, Matthew J. LINDON, Alexander G. PRESTON, Jonathan Thomas SEAL, Ian David WALL, Robert J. WATSON, James Michael WOOLVEN
  • PYRIDINONE DICARBOXAMIDE FOR USE AS BROMODOMAIN INHIBITORS
    Publication number: 20180282301
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy
    Type: Application
    Filed: September 20, 2016
    Publication date: October 4, 2018
    Inventors: Stephen John ATKINSON, Emmanuel Hubert, Lee Andrew HARRISON, Thomas HAYHOW, David HOUSE, Matthew J. LINDON, Alexander G. PRESTON, Jonathan Thomas SEAL, IAN David WALL, Robert J. WATSON, James Michael WOOLVEN
  • PYRIDINONE DICARBOXAMIDE FOR USE AS BROMODOMAIN INHIBITORS
    Publication number: 20180258044
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy
    Type: Application
    Filed: August 31, 2016
    Publication date: September 13, 2018
    Inventors: Stephen John ATKINSON, Helen Elizabeth AYLOTT, Anthony William James COOPER, Emmanuel Hubert DEMONT, Lee Andrew HARRISON, Thomas George Christopher HAYHOW, Matthew J. LINDON, Alexander G. PRESTON, Jonathan Thomas SEAL, Ian David WALL, Robert J. WATSON, James Michael WOOLVEN
  • 4-(8-methoxy-1-((1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1 H-imidazo[4,5-C]quinolin-7-yl)-3,5-dimethylisoxazole and its use as bromodomain inhibitor
    Patent number: 9861627
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: January 9, 2018
    Assignee: GlaxoSmithKline LLC
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • 4-(8-METHOXY-1-((1-METHOXYPROPAN-2-YL)-2-(TETRAHYDRO-2H-PYRAN-4-YL)-1 H-IMIDAZO[4,5-C]QUINOLIN-7-YL)-3,5-DIMETHYLISOXAZOLE AND ITS USE AS BROMODOMAIN INHIBITOR
    Publication number: 20170157113
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: February 17, 2017
    Publication date: June 8, 2017
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • 4-(8-methoxy-1-((1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole and its use as bromodomain inhibitor
    Patent number: 9610284
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: April 4, 2017
    Assignee: GlaxoSmithKline LLC
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • Sound treatment assembly for a fluid transmission line
    Patent number: 9587765
    Abstract: A sound treatment assembly includes an outlet member having a bore extending along a longitudinal axis, and a first flange portion is adapted to be coupled to portion of a valve body of a regulator valve. The first flange portion includes a contoured mating surface adapted to mate with a corresponding contoured portion of an exterior surface of the valve body. The outlet member also includes a second flange portion disposed at the second end. A diffuser assembly includes diffuser housing extending along the longitudinal axis, and a first flange portion is disposed at the first end of the diffuser housing and is adjacent to the second flange portion of the outlet member. One or more diffuser elements are disposed within an interior of the diffuser housing to reduce noise levels in the fluid exiting the outlet member.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: March 7, 2017
    Assignee: EMERSON PROCESS MANAGEMENT REGULATOR TECHNOLOGIES, INC.
    Inventors: Chun Lin, Robert J. Watson
  • 4-(8-METHOXY-1-((1-METHOXYPROPAN-2-YL)-2-(TETRAHYDRO-2H-PYRAN-4-YL)-1 H-IMIDAZO[4,5-C]QUINOLIN-7-YL)-3,5-DIMETHYLISOXAZOLE AND ITS USE AS BROMODOMAIN INHIBITOR
    Publication number: 20160317529
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: July 8, 2016
    Publication date: November 3, 2016
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • 4-(8-methoxy-1-((1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1 H-imidazo[4,5-C]quinolin-7-yl)-3,5-dimethylisoxazole and its use as bromodomain inhibitor
    Patent number: 9416130
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: August 16, 2016
    Assignee: GlaxoSmithKline LLC
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • 4-(8-METHOXY-1-((1-METHOXYPROPAN-2-YL)-2-(TETRAHYDRO-2H-PYRAN-4-YL)-1 H-IMIDAZO[4,5-C]QUINOLIN-7-YL)-3,5-DIMETHYLISOXAZOLE AND ITS USE AS BROMODOMAIN INHIBITOR
    Publication number: 20150315184
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: May 28, 2015
    Publication date: November 5, 2015
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • SOUND TREATMENT ASSEMBLY FOR A FLUID TRANSMISSION LINE
    Publication number: 20150300525
    Abstract: A sound treatment assembly includes an outlet member having a bore extending along a longitudinal axis, and a first flange portion is adapted to be coupled to portion of a valve body of a regulator valve. The first flange portion includes a contoured mating surface adapted to mate with a corresponding contoured portion of an exterior surface of the valve body. The outlet member also includes a second flange portion disposed at the second end. A diffuser assembly includes diffuser housing extending along the longitudinal axis, and a first flange portion is disposed at the first end of the diffuser housing and is adjacent to the second flange portion of the outlet member. One or more diffuser elements are disposed within an interior of the diffuser housing to reduce noise levels in the fluid exiting the outlet member.
    Type: Application
    Filed: April 21, 2015
    Publication date: October 22, 2015
    Inventors: Chun Lin, Robert J. Watson
  • 4-(8-methoxy-1-((1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1 H-imidazo[4,5-C]quinolin-7-yl)-3,5-dimethylisoxazole and its use as bromodomain inhibitor
    Patent number: 9067936
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: June 30, 2015
    Assignee: GlaxoSmithKline LLC
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • Tetrahydroquinoline derivatives useful as bromodomain inhibitors
    Patent number: 9029395
    Abstract: Tetrahydroquinoline derivatives, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: May 12, 2015
    Assignee: GlaxoSmithKline LLC
    Inventors: Dominique Amans, Emmanuel Hubert Demont, Darren Jason Mitchell, Robert J. Watson
  • 7-(3,5-dimethyl-4-isoxazolyl)-8-(methyloxy)-1H-imidazo[4,5-C]quinoline derivatives
    Patent number: 8846709
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: September 30, 2014
    Assignee: GlaxoSmithKline LLC
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • 4-(8-METHOXY-1-((1-METHOXYPROPAN-2-YL)-2-(TETRAHYDRO-2H-PYRAN-4-YL)-1 H-IMIDAZO[4,5-C]QUINOLIN-7-YL)-3,5-DIMETHYLISOXAZOLE AND ITS USE AS BROMODOMAIN INHIBITOR
    Publication number: 20140171462
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: August 15, 2012
    Publication date: June 19, 2014
    Applicant: GlaxcoSmithKline LLC
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • 7-(3,5-Dimethyl-4-Isoxazolyl)-8-(Methyloxy)-1H-Imidazo[4,5-C]Quinoline Derivatives
    Publication number: 20140045834
    Abstract: Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: April 19, 2012
    Publication date: February 13, 2014
    Applicant: GlaxoSmithKline LLC
    Inventors: Emmanuel Hubert Demont, Katherine Louise Jones, Robert J. Watson
  • Tetrahydroquinoline Derivatives Useful As Bromodomain Inhibitors
    Publication number: 20140039006
    Abstract: Tetrahydroquinoline derivatives, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: April 19, 2012
    Publication date: February 6, 2014
    Applicant: GlaxoSmithKline LLC
    Inventors: Dominique Amans, Emmanuel Hubert Demont, Darren Jason Mitchell, Robert J. Watson
  • PYRIDO[3,4-B]PYRAZINE DERIVATIVES AS SYK INHIBITORS
    Publication number: 20140005188
    Abstract: A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, and autoimmune conditions.
    Type: Application
    Filed: March 8, 2012
    Publication date: January 2, 2014
    Applicant: GLAXO GROUP LIMITED
    Inventors: Francis Louis Atkinson, Stephen John Atkinson, Michael David Barker, Clement Douault, Neil Stuart Garton, John Liddle, Vipulkumar Kantibhai Patel, Alexander G. Preston, Tracy Jane Shipley, David Matthew Wilson, Robert J. Watson