Patents by Inventor Robert Jacquier

Robert Jacquier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chiral polymers for the production of excess enantiomers
    Patent number: 5281750
    Abstract: The present invention relates to chiral supports and to their use in the asymmetric synthesis, deracemization and optical inversion of organic chiral compounds. In particular, the supports are used in combination with thermal equilibration of a species having a reactive achiral portion. Preferably, these supports are obtained by the copolymerization of at least one chiral unit and at least one functionalizing unit or by the polymerization of at least one chiral unit which is a source of said functionalizing unit. Optionally, a crosslinking agent is utilized. By utilizing these supports and thermal equilibration, excess enantiomers can be produced.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: January 25, 1994
    Assignee: Rhone-Poulenc Chimie
    Inventors: Robert Jacquier, Monique Calmes, Jacques Daunis
  • Chiral polymers for the synthesis of pure enantiomers of amino acids
    Patent number: 5280093
    Abstract: The present invention relates to chiral polymers and to their uses for operations of asymmetric synthesis, deracemization and optical inversion.These polymers are characterized in that they comprise:a chiral unita functionalizing unitan optional crosslinking unitApplication to chiral organic synthesis.
    Type: Grant
    Filed: April 14, 1993
    Date of Patent: January 18, 1994
    Assignee: Rhone-Poulenc Chimie
    Inventors: Robert Jacquier, Monique Calmes, Jacques Daunis
  • Process for preparing peptide synthons
    Patent number: 5138037
    Abstract: The present invention relates to a process for preparing optically active synthons, in which an oxygen-silylated amino acid or peptide having a protected nitrogenous group, is activated by a non-coordinated halogenated phosphorus derivative and is condensed with an N-silyl amino acid or peptide in which the acid group is protected.
    Type: Grant
    Filed: March 5, 1991
    Date of Patent: August 11, 1992
    Assignee: Rhone-Poulenc Chimie
    Inventors: Robert Jacquier, Jean Verducci, Virginie Pevere
  • Process for preparing peptide synthons
    Patent number: 5077387
    Abstract: The present invention relates to a process for preparing peptide synthons in which the optical purity of each of the peptides to be condensed is retained.According to this process, a silyl derivative of an amino acid or peptide, which is activated by a complex chloroimmonium salt, a complex coordinated phosphorus halide, oxyhalide salt or a complex oxalyl halide salt, is prepared. The activated peptide is then condensed with an N-silyl amino acid or peptide in which the acid group is protected.
    Type: Grant
    Filed: April 29, 1988
    Date of Patent: December 31, 1991
    Assignee: Rhone-Poulenc Chimie
    Inventors: Robert Jacquier, Jean Verducci, Michel Ibea
  • Acrylic copolymers of N-acryloylpolymethyleneimines or N-acryloyldialkylamides, N,N'-acryloyldiaminoalcanes and N-acryloylaminoacids (or esters) their preparation and use as cation exchangers
    Patent number: 4439545
    Abstract: The invention relates to new reticulated statistic acrylic copolymers that may be used in a very wide range of solvents (water, methylene chloride, chloroform, methanol, ethanol, dimethylformamide, pyridine,) stable between pH 1 and pH 14, to preparation process thereof and to their use in ion exchange chromatography.
    Type: Grant
    Filed: November 10, 1982
    Date of Patent: March 27, 1984
    Assignee: Societe d "Expansion Scientifique "Expansia"
    Inventors: Christian Aspisi, Bernard Calas, Jacques Daunis, Michel Follet, Robert Jacquier, Joseph Parello
  • Borane complexes
    Patent number: 4436919
    Abstract: This invention relates to new chiral organoboranes of the general formula ##STR1## in which X represents a methylene group or a sulphur atom, n and p are 0 or 1, and to a preparation process of these compounds, consisting in reacting a bicyclic substituted di- or tri-thiane with a borane such as B.sub.2 H.sub.6 or BH.sub.3 : Lewis base.
    Type: Grant
    Filed: March 17, 1982
    Date of Patent: March 13, 1984
    Assignee: Societe d'Expansion Scientifique "EXPANSIA"
    Inventors: Christian Aspisi, Marc Bonato, Robert Jacquier
  • Acrylic copolymers and their use in solid phase peptide synthesis
    Patent number: 4436874
    Abstract: The present invention relates to new amino-functionalized acrylic copolymers, their preparation and their use in peptide synthesis.
    Type: Grant
    Filed: November 10, 1982
    Date of Patent: March 13, 1984
    Assignee: Societe d'Expansion Scientifique "EXPANSIA"
    Inventors: Christian Aspisi, Bernard Calas, Jacques Daunis, Michel Follet, Robert Jacquier, Joseph Parello