Patents by Inventor Robert James Cotter

Robert James Cotter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110136692
    Abstract: The present invention relates to the use of mass spectrometry to analyze arrays. The present invention provides methods for characterizing solutions comprising one or more proteins using arrays and mass spectrometry. The arrays of the present invention are coated with porous gold and utilize hydrophobic and hydrophilic self-assembled monolayers.
    Type: Application
    Filed: February 19, 2009
    Publication date: June 9, 2011
    Applicant: The Johns Hopkins University
    Inventors: Robert James Cotter, Kenyon Mclane Evans-Nguyen, Heng Zhu, Sheng-Ce Tao
  • Patent number: 7825374
    Abstract: A tandem mass spectrometer includes a linear time-of-flight mass analyzer and curved field reflectron mass analyzer. The curved-field reflectron mass analyzer is disposed at an end of the linear time-of-flight mass analyzer such that ions having a plurality of ion masses formed in the linear time-of-flight analyzer such that ions having a plurality of ion masses formed in the linear time-of-flight analyzer enter the curved-field reflectron mass analyzer. The tandem mass spectrometer also includes a mass selection gate disposed between the time-of-flight mass analyzer and the curved-field reflectron mass analyzer. The mass selection gate selects an ion mass from the plurality of ion masses. Furthermore, the tandem mass spectrometer also includes a dissociating component located in a path of the ions formed in the linear time-of-flight analyzer. The dissociating component causes dissociation of the ions into a plurality of ion fragments.
    Type: Grant
    Filed: February 23, 2004
    Date of Patent: November 2, 2010
    Assignee: The Johns Hopkins University
    Inventors: Robert James Cotter, Benjamin D. Gardner, Robert D. English, Serguei A. Ilchenko
  • Patent number: 7576323
    Abstract: A point-of-care mass spectrometer system has a sampling system, an ionization component structured to receive a sample for analysis from the sampling system, a mass analyzer structured to receive a source of ions for analysis from the ionization component, and a detector structured to detect ions from the mass analyzer and to generate an output signal. The sampling system selects a subset of peptides from a sample by immunopurification of multiple histocompatability complexes and concentrates the subset of peptides to provide the sample to the ionization component.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: August 18, 2009
    Assignee: Johns Hopkins University
    Inventor: Robert James Cotter
  • Publication number: 20090175798
    Abstract: Provided are diagnostic and therapeutic methods of treating sarcoidosis comprising the use of microbial catalase-peroxidase protein, its peptide fragments, or derivatives thereof.
    Type: Application
    Filed: October 3, 2008
    Publication date: July 9, 2009
    Applicant: The Johns Hopkins University
    Inventors: David Robert Moller, Robert James Cotter, Ying Zhang
  • Publication number: 20080258054
    Abstract: A point-of-care mass spectrometer system has a sampling system, an ionization component structured to receive a sample for analysis from the sampling system, a mass analyzer structured to receive a source of ions for analysis from the ionization component, and a detector structured to detect ions from the mass analyzer and to generate an output signal. The sampling system selects a subset of peptides from a sample by immunopurification of multiple histocompatability complexes and concentrates the subset of peptides to provide the sample to the ionization component.
    Type: Application
    Filed: September 27, 2005
    Publication date: October 23, 2008
    Applicant: JOHNS HOPKINS UNIVERSITY
    Inventor: Robert James Cotter
  • Patent number: 7372021
    Abstract: A time-of-flight mass spectrometer which has an iron source, an evacuated tube proximate the ion source and adapted to receive ions from the ion source, and a detector disposed at an end of the evacuated tube opposite an end proximate the ion source. The ion source is constructed to generate an electric field that changes non-linearly as a function of position along a path from the ion source to the detector. The ion source is constructed to generate an electric field that changes as a function of time, the electric field being provided to accelerate ions from the ion source to the detector.
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: May 13, 2008
    Assignee: The Johns Hopkins University
    Inventors: Robert James Cotter, Benjamin D. Gardner, John F Holland
  • Patent number: 5721319
    Abstract: A polymer blend and a golf ball employing a cover formed of that polymer blend are disclosed. The polymer blend is made from about 5 to about 95 phr of the polymer blend. About 5 to about 95 phr resin is included in the blend. The ball that employs the cover of the polymer blend has excellent click and feel, as well as excellent spin characteristics.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: February 24, 1998
    Assignee: Acushnet Company
    Inventors: Jeffrey Lawrence Dalton, Robert James Cotter, Jr.
  • Patent number: 4018721
    Abstract: Sulfur dioxide can be adsorbed from gas mixtures using cross-linked, water-insoluble polymers of N-glycidylpiperazine or N-glycidyl polyalkylpiperazines as the adsorbents.
    Type: Grant
    Filed: February 4, 1976
    Date of Patent: April 19, 1977
    Assignee: Union Carbide Corporation
    Inventors: Robert James Cotter, Michael John Keogh, William Donald Heitz
  • Patent number: 4003848
    Abstract: Sulfur dioxide can be adsorbed from gas mixtures using cross-linked, water-insoluble polymers of N-glycidyl piperazine or N-glycidyl polyalkylpiperazines as the adsorbents.
    Type: Grant
    Filed: February 9, 1976
    Date of Patent: January 18, 1977
    Assignee: Union Carbide Corporation
    Inventors: Robert James Cotter, Michael John Keogh, William Donald Heitz