Patents by Inventor Robert Jeraj

Robert Jeraj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12562258
    Abstract: The present disclosure provides methods, systems, and non-transitory computer-readable media for assessment of disease treatment or progression on a lesion-by-lesion level. The systems and methods are based on measurements of a variety of features including total number of lesions, total number and proportion of lesions regressing or progressing, changes in dimensions of a lesion over time, and uptake values of a molecular imaging agent.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: February 24, 2026
    Assignee: AIQ Global Inc.
    Inventors: Robert Jeraj, Timothy Perk, Stephen Yip, S. Sean Houshmandi
  • Patent number: 12260941
    Abstract: A tool for assessing treatment options within a risk-benefit space (plotting risk against benefit) and provides a superimposed boundary indicating patient risk-benefit preference for assessment of these options. The patient risk-benefit preference can be used to identify a preferred treatment option, and interactive controls can be provided to change risk-benefit preference, risk categories, benefit categories, disease type, and the like.
    Type: Grant
    Filed: August 10, 2022
    Date of Patent: March 25, 2025
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Robert Jeraj, Daniel Tyler Huff
  • Publication number: 20250057472
    Abstract: A method and apparatus for tracking disease progression as revealed by multiple lesions perform a global optimization to identify corresponding lesions by overlap, for example, after outlines of the lesions have been morphologically dilated. A clustering algorithm addresses the problem of lesions separating into parts or joining together to provide a clear picture of disease progression.
    Type: Application
    Filed: November 5, 2024
    Publication date: February 20, 2025
    Inventors: Robert Jeraj, Victor Fernandes, Timothy Perk, Peter Ferjancic, Daniel Huff
  • Patent number: 12150776
    Abstract: A method and apparatus for tracking disease progression as revealed by multiple lesions perform a global optimization to identify corresponding lesions by overlap, for example, after outlines of the lesions have been morphologically dilated. A clustering algorithm addresses the problem of lesions separating into parts or joining together to provide a clear picture of disease progression.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: November 26, 2024
    Assignee: Wisconsin Alumni Research Foundation & AIQ Solutions, Inc.
    Inventors: Robert Jeraj, Victor Fernandes, Timothy Perk, Peter Ferjancic, Daniel Huff
  • Publication number: 20240341711
    Abstract: A method and apparatus for tracking disease progression as revealed by multiple lesions matches lesions between time-separated scans of a patient through a global process which assesses overlap between all pairs in the scan sequence and links lesion in different images to maximize overlap globally.
    Type: Application
    Filed: April 11, 2023
    Publication date: October 17, 2024
    Inventors: Robert Jeraj, Victor Fernandes
  • Publication number: 20240164709
    Abstract: A system for monitoring organ health during treatment for cancer and the like makes use of physiological imaging of the kind used for treatment monitoring and organ-specific processing to provide a comprehensive assessment of treatment side-effects.
    Type: Application
    Filed: January 26, 2024
    Publication date: May 23, 2024
    Inventors: Robert Jeraj, Daniel Huff, Timothy Perk, Stephen Yip, Glenn Liu
  • Patent number: 11918374
    Abstract: A system for monitoring organ health during treatment for cancer and the like makes use of physiological imaging of the kind used for treatment monitoring and organ-specific processing to provide a comprehensive assessment of treatment side-effects.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: March 5, 2024
    Assignees: Wisconsin Alumni Research Foundation, AIQ Global, Inc.
    Inventors: Robert Jeraj, Daniel Huff, Timothy Perk, Stephen Yip, Glenn Liu
  • Publication number: 20240055090
    Abstract: A tool for assessing treatment options within a risk-benefit space (plotting risk against benefit) and provides a superimposed boundary indicating patient risk-benefit preference for assessment of these options. The patient risk-benefit preference can be used to identify a preferred treatment option, and interactive controls can be provided to change risk-benefit preference, risk categories, benefit categories, disease type, and the like.
    Type: Application
    Filed: August 10, 2022
    Publication date: February 15, 2024
    Inventors: Robert Jeraj, Daniel Tyler Huff
  • Publication number: 20230046564
    Abstract: The present disclosure provides methods, systems, and non-transitory computer-readable media for assessment of disease treatment or progression on a lesion-by-lesion level. The systems and methods are based on measurements of a variety of features including total number of lesions, total number and proportion of lesions regressing or progressing, changes in dimensions of a lesion over time, and uptake values of a molecular imaging agent.
    Type: Application
    Filed: July 15, 2022
    Publication date: February 16, 2023
    Inventors: Robert JERAJ, Timothy PERK, Stephen YIP, S. Sean HOUSHMANDI
  • Publication number: 20220338805
    Abstract: A method and apparatus for tracking disease progression as revealed by multiple lesions perform a global optimization to identify corresponding lesions by overlap, for example, after outlines of the lesions have been morphologically dilated. A clustering algorithm addresses the problem of lesions separating into parts or joining together to provide a clear picture of disease progression.
    Type: Application
    Filed: April 26, 2021
    Publication date: October 27, 2022
    Inventors: Robert Jeraj, Victor Fernandes, Timothy Perk, Peter Ferjancic, Daniel Huff
  • Publication number: 20210345957
    Abstract: A system for monitoring organ health during treatment for cancer and the like makes use of physiological imaging of the kind used for treatment monitoring and organ-specific processing to provide a comprehensive assessment of treatment side-effects.
    Type: Application
    Filed: April 21, 2021
    Publication date: November 11, 2021
    Inventors: Robert Jeraj, Daniel Huff, Timothy Perk, Stephen Yip, Glenn Liu
  • Patent number: 10445878
    Abstract: A standardized skeleton template is used to normalize medical image data of the skeleton to eliminate variations in the medical image data related to physiological variations in a normal patient thereby better accentuating disease conditions.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: October 15, 2019
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Robert Jeraj, Tyler Bradshaw, Timothy Perk
  • Publication number: 20180330495
    Abstract: A standardized skeleton template is used to normalize medical image data of the skeleton to eliminate variations in the medical image data related to physiological variations in a normal patient thereby better accentuating disease conditions.
    Type: Application
    Filed: May 9, 2017
    Publication date: November 15, 2018
    Inventors: Robert Jeraj, Tyler Bradshaw, Timothy Perk
  • Patent number: 10007961
    Abstract: A treatment schedule for radiopharmaceuticals is developed by collecting a volumetric history of tissue uptake in identified volumes of interest using emitted-radiation scans and relating this data to a treatment-radiopharmaceutical to develop a quantitatively accurate radiation treatment schedule of delivery amounts and delivery times of the treatment-radiopharmaceutical. This data may also be used to model biological effective dose and to prepare augmenting external radiation beam treatment schedules.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: June 26, 2018
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Joseph J. Grudzinski, Robert Jeraj, Wolfgang A. Tome, Jamey P. Weichert
  • Patent number: 9603567
    Abstract: A sensitive method of assessing treatment using molecular and anatomical imaging scans provides automatic tumor identification and quantification within anatomical zones based on treatment criteria. Absolute or comparative measures of tumors in pre- and/or post-scans are thereby isolated from other tissue to accentuate the progress of the treatment when multiple scattered disease lesions are present.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: March 28, 2017
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Robert Jeraj, Glenn Liu
  • Patent number: 9355447
    Abstract: A system and method for analyzing medical images of a subject includes acquiring the medical images of the subject and texture images. A computer system determines, using the medical images and the texture feature images, a plurality of segmentation surfaces by iteratively adjusting a relationship between a region growing algorithm that selects a region of interest (ROI) to determine a given segmentation surface and cost function for evaluating the given segmentation surface. The computer system generates a report using the plurality of segmentation surfaces indicating at least boundaries between anatomical structures with functional differences in the medical images.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: May 31, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Paulina E. Galavis, Bhudatt Paliwal, James Holden, Robert Jeraj
  • Publication number: 20160100795
    Abstract: A sensitive method of assessing treatment using molecular and anatomical imaging scans provides automatic tumor identification and quantification within anatomical zones based on treatment criteria. Absolute or comparative measures of tumors in pre- and/or post-scans are thereby isolated from other tissue to accentuate the progress of the treatment when multiple scattered disease lesions are present.
    Type: Application
    Filed: October 19, 2015
    Publication date: April 14, 2016
    Inventors: Robert Jeraj, Glenn Liu
  • Patent number: 9161720
    Abstract: A sensitive method of assessing treatment using molecular and anatomical imaging scans provides automatic tumor identification and quantification within anatomical zones based on treatment criteria. Absolute or comparative measures of tumors in pre- and/or post-scans are thereby isolated from other tissue to accentuate the progress of the treatment when multiple scattered disease lesions are present.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: October 20, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Robert Jeraj, Glenn Liu
  • Publication number: 20150055849
    Abstract: A system and method for analyzing medical images of a subject includes acquiring the medical images of the subject and texture images. A computer system determines, using the medical images and the texture feature images, a plurality of segmentation surfaces by iteratively adjusting a relationship between a region growing algorithm that selects a region of interest (ROI) to determine a given segmentation surface and cost function for evaluating the given segmentation surface. The computer system generates a report using the plurality of segmentation surfaces indicating at least boundaries between anatomical structures with functional differences in the medical images.
    Type: Application
    Filed: August 21, 2013
    Publication date: February 26, 2015
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Paulina E. Galavis, Bhudatt Paliwal, James Holden, Robert Jeraj
  • Publication number: 20140276035
    Abstract: A sensitive method of assessing treatment using molecular and anatomical imaging scans provides automatic tumor identification and quantification within anatomical zones based on treatment criteria. Absolute or comparative measures of tumors in pre- and/or post-scans are thereby isolated from other tissue to accentuate the progress of the treatment when multiple scattered disease lesions are present.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: ROBERT JERAJ, GLENN LIU