Abstract: A driveline assembly for equipment, such as a tiller, includes a pair of counter-rotating bevel gears supported on a wheel shaft and rotatable relative to the wheel shaft. The driveline assembly includes a first slider gear movable between a first position in which the first slider gear is engaged with a first bevel gear of the pair of bevel gears, and a second position in which the first slider gear is engaged with a second bevel gear of the pair of bevel gears. When the first slider gear is engaged with the first bevel gear, the first bevel gear becomes operatively connected to a rotatable tine shaft to rotate tines in a first direction. When the first slider gear is engaged with the second bevel gear, the second bevel gear becomes operatively connected to the rotatable tine shaft to rotate the tines in a second direction opposite the first direction.

Abstract: Provided herein are methods of treating cancer, an infectious disease, or an infection, which comprise administering to a human patient in need thereof: (a) a TIGIT antagonist; (b) a PD-1 antagonist; and (c) lenvatinib represented by Formula (I), or a pharmaceutically acceptable salt thereof. Also provided are kits containing such agents and uses of therapeutic combinations of such agents for the treatment of cancer, an infectious disease, or an infection.

Abstract: An aerosol generating article for use with an aerosol generating device including a magnetic field generator includes first and second discrete compartments configured to contain respectively a first aerosol generating substance and a second aerosol generating substance, and an inductively heatable susceptor configured to be inductively heated by the magnetic field generator. The inductively heatable susceptor has a first part positioned in the first compartment and a second part positioned in the second compartment.

Abstract: Described are improved systems and methods for navigation and manipulation of interactable objects in a 3D mixed reality environment. Improved systems and methods are provided to implement physical manipulation for creation and placement of interactable objects, such as browser windows and wall hangings. A method includes receiving data indicating a selection of an interactable object contained within a first prism at the start of a user interaction. The method also includes receiving data indicating an end of the user interaction with the interactable object. The method further includes receiving data indicating a physical movement of the user corresponding to removing the interactable object from the first prism between the start and the end of the user interaction. Moreover, the method includes creating a second prism to contain the data associated with the interactable object at the end of the user interaction with the interactable object.

Abstract: The present invention relates to peptide conjugates of microtubule-targeting agents such as maytansinoid derivatives which are useful for the treatment of diseases such as cancer.

Abstract: The present disclosure relates to a fluid dispensing device (1) comprising: —a housing (10) to accommodate a container (110) filled a fluid, —a outlet orifice (3), —a discharge mechanism (130) operable for spray discharging multiple doses of the fluid via the outlet orifice (3), —a mechanical energy storage (50) coupled to the discharge mechanism (130), reversibly transferable between a preloaded state and an unloaded state and configured to store mechanical energy in the preloaded state effective to produce the spray discharging of the fluid, —a releasable interlock (70) configured to retain the mechanical energy storage (50) in the preloaded state, —a trigger mechanism (90) operationally engageable with the interlock (70) and operable i) to release a first portion of the mechanical energy stored in the mechanical energy storage (50) when actuated for a first time and ii) to release at least a second portion of the mechanical energy stored in the mechanical energy storage (50) when actuated for a second time

Abstract: The disclosure relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO into one or more first products which, in turn, may be incorporated into an article of manufacture or one or more second products. Further, the disclosure relates to improving carbon capture and/or efficiency.

Abstract: The present disclosure relates to a fluid dispensing device (10), the fluid dispensing device (1) comprising: a housing (10) to accommodate a container (110) filled with a fluid, wherein the housing (10) comprises a sidewall 118) extending along a longitudinal direction (z), —an outlet orifice (3), —a discharge mechanism (130) operable for spray discharging at least one or multiple doses of the fluid via the outlet orifice (3), —a protective cap (12) pivotally supported on or by the housing (10) between an open position and a closed position, wherein when in the closed position the outlet orifice (3) is effectively covered by the protective cap (12), —a mechanical energy storage (50) coupled to the discharge mechanism (130), reversibly transferable between a preloaded state and an unloaded state and configured to store mechanical energy in the preloaded state effective to produce the spray discharging of the fluid, —a biasing mechanism (150) comprising a biasing member (160) operationally coupled to the prote

Abstract: Security measures for signal paths with tree structures can be implemented at design phase using an EDA software program or tool with security feature functionality that, when executed by a computing system, directs the computing system to: display a canvas through which components of a circuit are arranged; and provide a menu of commands, including an option to add components from a library to the canvas and an option to secure a tree. In response to receiving a selection of the option to secure the tree, the system can be directed to add a hardware countermeasure coupled to at least two lines or terminal nodes of a tree structure identified from components on the canvas or in a netlist corresponding to a circuit's design.

Abstract: A respiratory pressure therapy (RPT) device is disclosed for treatment of respiratory-related disorders. The RPT device includes a pressure generator, a pneumatic block, a chassis and a device outlet for delivering a supply of flow of gas to a patient interface. The RPT device also comprises an integrated humidifier including a water reservoir. An RPT device is also disclosed that includes a wireless data communication interface integrated with the housing and configured to connect to another device or a network.

Abstract: In implementations of systems for generating review likelihoods for sets of code, a computing device implements a review system to compile input data based on code data describing information associated with a set of new code to be incorporated into a set of existing code and reviewer data describing information associated with a potential reviewer of sets of code. The review system processes the input data using a machine learning model trained on training data to generate review likelihoods for potential reviewers of sets of code to be selected to review sets of new code. A review likelihood for the potential reviewer of sets of code to be selected to review the set of new code is generated using the machine learning model based on processing the input data. The review system generates an indication of the review likelihood for display in a user interface.

Abstract: In accordance with some embodiments, a system for controlling an aircraft is provided. The system can include a computing device, wherein the computing device includes at least one processor configured to control a flight path angle of the aircraft, and wherein the aircraft is a blown lift aircraft. The system can also include a control operator communicatively coupled to the computing device, wherein the control operator is configured to have at least two selectable settings. The system can also include at least two thrust-producing devices operatively coupled to a pair of wings on the aircraft and communicatively coupled to the computing device. The computing device may control the flight path angle of the aircraft by selectively operating the at least two thrust-producing devices based on a plurality of conditions provided by a plurality of sensors on the aircraft and a selected setting of the control operator.

Abstract: The invention relates to chemical compositions comprising a benzalkonium compound, a penetration enhancer, a surfactant, and a polymeric film-forming agent, and their use to control fungi or fungus-like pathogens on plants and in soil.

Abstract: Systems, devices, methods, and implementations related to contact detection are described herein. In one aspect, a system is provided. The system includes a first piezoelectric microelectromechanical systems (MEMS) transducer coupled to configured to generate a first analog signal when the first analog signal is transduced from vibrations propagating through the object. The system includes a second piezoelectric MEMS transducer having configured to generate a second analog signal transduced from acoustic vibrations at a location of the object, and classification circuitry coupled to the output of first piezoelectric MEMS transducer and the output of the second piezoelectric MEMS transducer, where the classification circuitry is configured to process data from the first analog signal and data from the second analog signal, and to categorize combinations of the first analog signal and the second analog signal received during one or more time frames.

Abstract: The present disclosure relates to a mechanical energy storage for a fluid dispensing device (10), the mechanical energy storage comprising:—a first drive spring (51) extending along a longitudinal direction (z),—the drive spring (51) comprising a first longitudinal end (53) to engage with a housing (10) of the fluid dispensing device (1) and a second longitudinal end (54) opposite to the first longitudinal end (53) to engage with a driver (30) movable relative to the housing (10) along the longitudinal direction (z),—wherein the mechanical energy storage (50) is reversibly transferable into a pre-loaded state by resiliently compressing the first drive spring (51) in the longitudinal direction (z) to thereby induce a resilient deformation of the first drive spring (51) in a first direction (y) transverse to the longitudinal direction (z), and-wherein the mechanical energy storage (50) is transferable from the pre-loaded state into an unloaded state by allowing the first drive spring (51) to relax into or towar

Abstract: A method for making a semiconductor gate-all-around (GAA) device may include forming source and drain regions on a semiconductor substrate, forming a plurality of semiconductor nanostructures extending between the source and drain regions, and forming a gate surrounding the plurality of semiconductor nanostructures in a gate-all-around arrangement. Furthermore, the method may include forming at least one superlattice may be within at least one of the nanostructures. The at least one superlattice may include a plurality of stacked groups of layers, with each group of layers including a plurality of stacked base semiconductor monolayers defining a base semiconductor portion, and at least one non-semiconductor monolayer constrained within a crystal lattice of adjacent base semiconductor portions.

Abstract: The present disclosure relates to methods for characterizing cancer testis antigen burden (“CTAB”), for predicting cancer survival outcomes using CTAB analysis, and for recommending and/or treating cancer using CTAB analysis. Particularly, aspects are directed to measuring expression of a panel of cancer testis antigen (CTA) gene markers in a tumor sample from a subject, determining a CTAB based on the measured expression of the CTA gene markers, classifying, by comparing to a reference CTAB score from the same cancer or tumor type, the CTAB score as a high-CTAB score or a low-CTAB score, and identifying the subject as responsive to a treatment wherein (i) the high-CTAB score is indicative of responsiveness to the treatment, or (ii) the low-CTAB score is indicative of responsiveness to the treatment.

Abstract: Systems, methods, and apparatus to select an enhanced write pulse for a write operation in a memory device. In one approach, stronger reset pulses are triggered when there is an increased risk of memory cell threshold voltage degradation. Memory cells read by a relatively higher number of read operations are recorded by a controller of a memory device by updating a lookup table with addresses of the memory cells read. For a new write operation, the controller determines if a reset on set write operation is to be performed. The controller also searches the lookup table to determine if an address for the target bits or codeword of the write operation are in the lookup table. If both conditions are satisfied, then the magnitude of the write pulse is increased for programming the memory cells.

Abstract: Gearboxes for a skid steered vehicle including layouts in which all electric propulsion drive motors and electric steering motors are located on one side of the gearbox, and layouts in which the drive inputs of the electric propulsion drive motors are located face to face. Gear change units and gear packaging configurations suitable for such gearboxes.

Abstract: Embodiments of the present disclosure include systems, methods, and non-transitory computer-readable storage media for automated determination of a patient tumor-immune phenotype from immunofluorescence (IF) image analysis of pathology slides based on a tumor infiltrating lymphocytes score, a non-tumor infiltrating lymphocytes score, and a non-tumor infiltrating lymphocytes at tumor margin score.