Abstract: Provided is a method of characterising a polynucleotide using a transmembrane pore, wherein the pore is a double pore comprising a first Csg G pore, or a homologue thereof, and second CsgG pore, or a homologue thereof.

Abstract: An energy management system and methods of using the same are disclosed. The energy management system is configured to distribute power plant tasks. Energy management system tasks are received at the energy management system. At least a portion of the received tasks are passed over a network from the energy management system to a power plant lead controller in a cluster of nodes, the cluster of nodes comprising electronic devices configured to control power plant equipment, the cluster of nodes comprising the power plant lead controller and a plurality of power plant follower controllers, the cluster of nodes configured to provide a plurality of combinations of redundancy to control power plant equipment. The power plant lead controller delegates, in real time, tasks to the plurality of power plant follower controllers. At least one of the cluster of nodes is configurable to be in hot standby mode.

Abstract: An energy management system and methods of using the same are disclosed. The energy management system is configured to deploy a first instantiation of a first hardware driver at a first electronic control device collocated with a first power plant apparatus, wherein the first hardware driver is configured to communicate with and enable control of the first power plant apparatus. The energy management system is configured to detect that the first instantiation of the first hardware driver at the first electronic control device has failed, and at least partly in response to detecting that the first instantiation of the first hardware driver at the first electronic control device has failed, utilize a second instantiation of the first hardware driver, stored in memory remote from the first electronic control device, to enable control of the first power plant apparatus.

Abstract: An attraction system has a plurality of show effects, a handheld or wearable device, and a control system. The control system is configured to perform operations that include monitoring a parameter of the handheld or wearable device, determining that the parameter is indicative of an undesirable utilization of the attraction system, and controlling the handheld or wearable device, at least one show effect of the plurality of show effects, or both. The control system is also configured to provide guidance to change the parameter in response to the determination that the parameter is indicative of the undesirable utilization of the attraction system.

Abstract: Use of a subcutaneously administered dose of between about 1.25 mg and 1.75 mg of bremelanotide or a pharmaceutically acceptable salt of bremelanotide for the treatment of female sexual dysfunction in women while reducing or minimizing undesirable side effects.

Abstract: The present invention relates to novel protein pores and their uses in analyte detection and characterisation. The invention particularly relates to an isolated pore complex formed by a CsgG-like pore and a modified CsgF peptide, or a homologue or mutant thereof, thereby incorporating an additional channel constriction or reader head in the nanopore. The invention further relates to a transmembrane pore complex and methods for production of the pore complex and for use in molecular sensing and nucleic acid sequencing applications.

Abstract: The present disclosure provides improved octave key systems for use with (e.g., incorporation into) an instrument in the bassoon family.

Abstract: The present disclosure provides vent nibs for use with (e.g., incorporation into) a woodwind instrument, such as a bassoon.

Abstract: A control system may include a processor, a power source, optionally an antenna, optionally a communication device, optionally one or more cameras, one or more motion sensors, and optionally one or more electromechanical latches. The one or more motion sensors are configured to create signals indicative of one or both of: a presence of a target animal, or a direction of travel of an animal, wherein the processor is configured to process the signals indicative of one or both of: a presence of the target animal, or the direction of travel of an animal, and wherein the system is configured to output an actuation signal to actuate closure of one or more containments of a remote trap structure based on one or both of: the determined presence of the animal, or the determined direction of travel of the animal.

Abstract: The present disclosure provides vent nibs for use with (e.g., incorporation into) a woodwind instrument, such as a bassoon.

Abstract: A trap for large animals. The system utilizes multi-containment areas for improved efficiency in herd animal trapping. The outer containment zone of the system is designed in such a way to promote animals further into the inner containment zone. The improved efficiency lowers overall cost of trap operation in terms of time, consumable bait replenishment and number of attempts on target animal groups. The system allows for independent and remote actuation of containment zone gates. Data is transmitted to a remote user and remote actuation of attracting or deterring audio can be done during trapping process. The architecture of the trap dissuades animals capable of jumping from doing so over the containment walls.

Abstract: The present disclosure provides improved octave key systems for use with (e.g., incorporation into) an instrument in the bassoon family.

Abstract: The invention relates generally to chimeric viral fusion proteins comprising the ectodomain and optionally the transmembrane domain of a first viral fusion protein (e.g., a spike protein of a coronavirus) and the cytoplasmic domain of a second viral fusion protein (e.g. RSV), immunogenic compositions comprising such chimeric proteins, and methods of use of same.

Abstract: Embodiments of the present disclosure relate to mount apparatuses for digital micromirror devices of digital lithography systems and methods of mounting the digital micromirror devices. The mount apparatuses described herein retain spatial light modulators, such as DMDs. The mount apparatus enables the flattening of the DMD by providing a force such that the pair of contact pads contact the DMD. The DMD is positioned in a mounting frame of the mount apparatus. Contact pads of the mounting frame are operable to apply pressure to the DMD.

Abstract: Embodiments disclosed herein include electronic packages. In an embodiment, an electronic package comprises a substrate with a first surface and a second surface, where the substrate comprises glass. In an embodiment, the electronic package further comprises a via opening through the substrate, where sidewalls of the via opening have a root mean squared (RMS) surface roughness that is approximately 100nm or greater. In an embodiment, the electronic package further comprises a liner over the sidewalls of the via opening, where an RMS surface roughness of the liner is approximately 50nm or smaller. An electronic package may further comprise a via through the via opening.

Abstract: A content processing system for an amusement park attraction includes a processor configured to receive a data stream including one or more control instructions for output of amusement content. The processor is also configured to identify one or more operational characteristics of an accessory. The processor is also configured to, based on the one or more operational characteristics, effectuate modification of the data stream to generate a modified data stream including one or more updated control instructions for output of adjusted amusement content to be presented to a user via the accessory. The processor is also configured to transmit the modified data stream to the accessory.

Abstract: A washing machine includes a power source, a drum, and a transmission. The transmission is configured to deliver power from the power source to the drum. The transmission includes a housing, a shaft, and a bushing. The housing defines a cavity. The shaft is disposed within the cavity and is configured to receive power from the power source. The bushing is disposed about the shaft. The bushing defines grooves that establish fluid communication between the cavity and a space that is defined between an inner diameter of the bushing and an outer diameter of the input shaft.

Abstract: The present invention relates to novel protein pores and their uses in analyte detection and characterisation. The invention particularly relates to an isolated pore complex formed by a CsgG-like pore and a modified CsgF peptide, or a homologue or mutant thereof, thereby incorporating an additional channel constriction or reader head in the nanopore. The invention further relates to a transmembrane pore complex and methods for production of the pore complex and for use in molecular sensing and nucleic acid sequencing applications.

Abstract: A washing machine includes a power source, a drum, and a transmission. The transmission is configured to deliver power from the power source to the drum. The transmission includes a housing, a shaft, and a bushing. The housing defines a cavity. The shaft is disposed within the cavity and is configured to receive power from the power source. The bushing is disposed about the shaft. The bushing defines grooves that establish fluid communication between the cavity and a space that is defined between an inner diameter of the bushing and an outer diameter of the input shaft.

Abstract: The present invention relates to novel protein pores and their uses in analyte detection and characterisation. The invention particularly relates to an isolated pore complex formed by a CsgG-like pore and a modified CsgF peptide, or a homologue or mutant thereof, thereby incorporating an additional channel constriction or reader head in the nanopore. The invention further relates to a transmembrane pore complex and methods for production of the pore complex and for use in molecular sensing and nucleic acid sequencing applications.