Patents by Inventor Robert Joseph Hughes

Robert Joseph Hughes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESSES FOR THE PREPARATION OF 4-{8-AMINO-3-[(2S)-1-(BUT-2-YNOYL)-PYRROLIDIN-2-YL]IMIDAZO[1,5-a]-PYRAZIN-1-YL}N-(PYRIDIN-2-YL)-BENZAMIDE
    Publication number: 20240317766
    Abstract: The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.
    Type: Application
    Filed: May 9, 2024
    Publication date: September 26, 2024
    Inventors: Paul Allen BETHEL, Lai Chun CHAN, Katie Grace COOPER, Robert John COX, Michael David GOLDEN, Shaun Alan HUGHES, Lucinda Victoria JACKSON, Kirsty Jane MILLARD, Andrew John PHILLIPS, Alexander James TELFORD, Jerry EVARTS, Michael Joseph LAWLER, Remy E. J. N. LITJENS, Peter Johannes Servaas Savio VAN EIJK, Mathilda Maria Henrica VERSTAPPEN, Frank L. M. VOS, Eric Jurriën ZIJP, Qiu JUNYING, Rustam Ferdinand GARREY, David Allen SHORT, Angang WANG
  • Systems, Methods, and Apparatuses for Producing and Packaging Fluids
    Publication number: 20240277574
    Abstract: A liquid concentrate generation system may comprise a manifold having an inlet receptacle including a first piercing member, an outlet receptacle including a second piercing member, and a flow channel connecting the inlet receptacle and outlet receptacle. The system may further comprise a cartridge having an inlet port and an outlet port sealed by a respective first and second cover. The inlet and outlet port may be respectively configured to displace within the inlet receptacle and outlet receptacle from an unspiked position to a spiked position. First and second piercing members may be in communication with the flow channel and spaced apart respectively from the first and second cover in the unspiked position. The first and second piercing members may be isolated from the flow channel and may respectively puncture the first and second cover in the spiked position.
    Type: Application
    Filed: April 12, 2024
    Publication date: August 22, 2024
    Inventors: Ryan P. Wood, Michael J. Haynes, Hans Erik Johnson, Thaddeus Joseph Hughes, Robert Houston Lawler, JR.
  • Trocar with reinforced obturator shaft
    Patent number: 6656198
    Abstract: In accordance with the present invention there is provided an obturator for penetrating body tissue which contains a handle and a shaft. The shaft has a proximal end attached to the handle and a distal end extending from it. The handle and shaft are formed from a single piece of molded polymer. A substantially rigid reinforcing member which is formed from a material having a greater rigidity than the molded polymer is disposed along the shaft.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: December 2, 2003
    Assignee: Ethicon-Endo Surgery, Inc.
    Inventors: Mark Tsonton, Robert Joseph Hughes, Saleem Qureshi
  • Trocar with reinforced obturator shaft
    Publication number: 20020183775
    Abstract: In accordance with the present invention there is provided an obturator for penetrating body tissue which contains a handle and a shaft. The shaft has a proximal end attached to the handle and a distal end extending from it. The handle and shaft are formed from a single piece of molded polymer. A substantially rigid reinforcing member which is formed from a material having a greater rigidity than the molded polymer is disposed along the shaft.
    Type: Application
    Filed: June 1, 2001
    Publication date: December 5, 2002
    Inventors: Mark Tsonton, Robert Joseph Hughes, Saleem Qureshi