Abstract: A nasal assembly for delivering breathable gas to a patient includes a frame having lateral connector, a cushion with a pair of nozzles, and a clip to secure the cushion to the frame. The frame includes a vent channel and a plurality of vent holes. The frame/cushion includes structure (lugs/cut outs) to prevent the assembly of an unvented frame with an unvented cushion, for safety purposes. The frame includes cored portions that interface with corner lugs provided on the cushion. A patient interface includes a frame, a cushion (nasal mask, nasal-oro mask, nozzles, etc.) and a vent assembly including a pattern of vent holes including at least two rows.

Abstract: A mask cushion or a mask assembly therewith provides a comfortable and effective seal for provision of a gas therapy by a respiratory treatment apparatus. The mask cushion may be integrated with or coupled to a mask frame. The mask cushion typically includes an inner cushion component. The mask cushion also includes a patient facial-contact side portion with a chamber and a barrier to form the chamber that may be flexible. The chamber may serve as an outer layer with respect to the inner cushion component. The chamber may be partially or completely filled with a gas, fluid or gel. The inner cushion may be formed with a soft flexible material such as an elastomer or foam, etc. The barrier may be a membrane and may also be soft flexible material.

Abstract: A nasal assembly for delivering breathable gas to a patient includes a frame having lateral connector, a cushion with a pair of nozzles, and a clip to secure the cushion to the frame. The frame includes a vent channel and a plurality of vent holes. The frame/cushion includes structure (lugs/cut outs) to prevent the assembly of an unvented frame with an unvented cushion, for safety purposes. The frame includes cored portions that interface with corner lugs provided on the cushion. A patient interface includes a frame, a cushion (nasal mask, nasal-oro mask, nozzles, etc.) and a vent assembly including a pattern of vent holes including at least two rows.

Abstract: Differentiating benign cutaneous lesions from melanoma is an imprecise and subjective endeavor. The use of micro-RNAs has been investigated, but results have not been consistent across studies and clinical applications are lacking. The invention provides new micro-RNA signatures for differentiating benign lesions from melanoma. The micro-RNA signatures are robust, being stable across detection platforms, diverse sample types, and patient populations. The diagnostic methods based on these signatures control for variations in lesion composition and sample diversity, and permit cross-platform comparisons. The micro-RNA signatures and methods are amenable to the use of samples from convenient non-invasive tape strip biopsy.

Abstract: A vent arrangement is provided to a mask or associated conduit to discharge exhaled gas from the mask to atmosphere. The vent arrangement is structured to diffuse the exhaust vent flow to produce less air jetting, thereby increasing the comfort of the patient and their bed partner. For example, the vent arrangement may include one or more grill components and/or media constructed and arranged to diffuse vent flow.

Abstract: A nasal assembly for delivering breathable gas to a patient includes a frame having lateral connector, a cushion with a pair of nozzles, and a clip to secure the cushion to the frame. The frame includes a vent channel and a plurality of vent holes. The frame/cushion includes structure (lugs/cut outs) to prevent the assembly of an unvented frame with an unvented cushion, for safety purposes. The frame includes cored portions that interface with corner lugs provided on the cushion. A patient interface includes a frame, a cushion (nasal mask, nasal-oro mask, nozzles, etc.) and a vent assembly including a pattern of vent holes including at least two rows.

Abstract: A mask cushion or a mask assembly therewith provides a comfortable and effective seal for provision of a gas therapy by a respiratory treatment apparatus. The mask cushion may be integrated with or coupled to a mask frame. The mask cushion typically includes an inner cushion component. The mask cushion also includes a patient facial-contact side portion with a chamber and a barrier to form the chamber that may be flexible. The chamber may serve as an outer layer with respect to the inner cushion component. The chamber may be partially or completely filled with a gas, fluid or gel. The inner cushion may be formed with a soft flexible material such as an elastomer or foam, etc. The barrier may be a membrane and may also be soft flexible material.

Abstract: A vent arrangement is provided to a mask or associated conduit to discharge exhaled gas from the mask to atmosphere. The vent arrangement is structured to diffuse the exhaust vent flow to produce less air jetting, thereby increasing the comfort of the patient and their bed partner. For example, the vent arrangement may include one or more grill components and/or media constructed and arranged to diffuse vent flow.

Abstract: A nasal assembly for delivering breathable gas to a patient includes a frame having lateral connector, a cushion with a pair of nozzles, and a clip to secure the cushion to the frame. The frame includes a vent channel and a plurality of vent holes. The frame/cushion includes structure (lugs/cut outs) to prevent the assembly of an unvented frame with an unvented cushion, for safety purposes. The frame includes cored portions that interface with corner lugs provided on the cushion. A patient interface includes a frame, a cushion (nasal mask, nasal-oro mask, nozzles, etc.) and a vent assembly including a pattern of vent holes including at least two rows.

Abstract: An electrical system includes first, second and third busses; a first interrupter electrically connected between the first and second busses; at least one of a shorting apparatus operatively associated with the first or second bus, and the first interrupter comprising a trip coil; a current sensor to sense a fault current flowing in the first bus and responsively output a first signal; a number of light sensors to sense an arc flash operatively associated with a number of the first, second or third busses and responsively output a second signal; a second interrupter electrically connected between the second and third power busses and output a third signal; and a circuit to invert the third signal to provide a fourth signal, and to operate the at least one of the shorting apparatus and the trip coil responsive to an AND of the first, second and fourth signals.

Abstract: A nasal assembly for delivering breathable gas to a patient includes a frame having lateral connector, a cushion with a pair of nozzles, and a clip to secure the cushion to the frame. The frame includes a vent channel and a plurality of vent holes. The frame/cushion includes structure (lugs/cut outs) to prevent the assembly of an unvented frame with an unvented cushion, for safety purposes. The frame includes cored portions that interface with corner lugs provided on the cushion. A patient interface includes a frame, a cushion (nasal mask, nasal-oro mask, nozzles, etc.) and a vent assembly including a pattern of vent holes including at least two rows.

Abstract: An apparatus includes first and second components. A track supports one of the components for movement toward the other of the components. A first connector is mounted on the first component. The first connector retains an end portion of a first fiber optic cable, and has a first alignment portion. A second connector retains an end portion of a second fiber optic cable, and has a second alignment portion. The second alignment portion guides the second fiber optic cable radially into coaxial alignment with the first fiber optic cable upon movement of the first alignment portion against the second alignment portion. A floating mount device supports the second connector on the second component for guided movement radially relative to the second component upon movement of the first alignment portion against the second alignment portion.

Abstract: A breathing assistance device includes a gas regulating valve. The gas regulating valve is operated by a linear actuator. The linear actuator may include a movable member that moves an obstruction member between an open position and a closed position. The linear actuator is isolated from a gas flow path through the valve.

Abstract: A breathing assistance device includes a gas regulating valve (1300). The gas regulating valve is operated by a linear actuator (1330). The linear actuator may include a movable member that moves an obstruction member between an open position and a closed position. The linear actuator is isolated from a gas flow path through the valve.

Abstract: An update change request that is made against attributes of a directory object causes automatically collection of customized information for an initiator of the request. A correlation identifier for the change request is generated. The changes to the attributes are processed to update the directory object and the customized information is updated to an extension attribute for the directory object. A unique audit event is raised for each changed attribute including the extension attribute and each audit event includes the correlation identifier.

Abstract: An arc quenching device creates a fault on a bus. A lockout mechanism of a circuit breaker feeding the bus is responsively actuated. Actuating the lockout mechanism may include releasing a spring-loaded mechanism mounted on a cassette that holds the circuit breaker to cause the mechanism to engage a lockout member of the circuit breaker.

Abstract: An arc quenching device creates a fault on a bus. A lockout mechanism of a circuit breaker feeding the bus is responsively actuated. Actuating the lockout mechanism may include releasing a spring-loaded mechanism mounted on a cassette that holds the circuit breaker to cause the mechanism to engage a lockout member of the circuit breaker.

Abstract: A vent arrangement is provided to a mask or associated conduit to discharge exhaled gas from the mask to atmosphere. The vent arrangement is structured to diffuse the exhaust vent flow to produce less air jetting, thereby increasing the comfort of the patient and their bed partner. For example, the vent arrangement may include one or more grill components and/or media constructed and arranged to diffuse vent flow.

Abstract: An electrical system includes first, second and third busses; a first interrupter electrically connected between the first and second busses; at least one of a shorting apparatus operatively associated with the first or second bus, and the first interrupter comprising a trip coil; a current sensor to sense a fault current flowing in the first bus and responsively output a first signal; a number of light sensors to sense an arc flash operatively associated with a number of the first, second or third busses and responsively output a second signal; a second interrupter electrically connected between the second and third power busses and output a third signal; and a circuit to invert the third signal to provide a fourth signal, and to operate the at least one of the shorting apparatus and the trip coil responsive to an AND of the first, second and fourth signals.

Abstract: A vent arrangement is provided to a mask or associated conduit to discharge exhaled gas from the mask to atmosphere. The vent arrangement is structured to diffuse the exhaust vent flow to produce less air jetting, thereby increasing the comfort of the patient and their bed partner. For example, the vent arrangement may include one or more grill components and/or media constructed and arranged to diffuse vent flow.