Patents by Inventor Robert Justice Shartle
Robert Justice Shartle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11654431Abstract: Described herein are various inventions and embodiments thereof, directed to systems, devices, and methods for analysis of a biofluid, as well as controlling a biofluid analysis system using a microfluidic device. Embodiments of biofluid analysis systems disclosed herein may provide analysis of a biofluid to identify and characterize one or more analytes. An apparatus may include a first layer defining a first opening and a second opening. The first layer may be substantially transparent. A second layer may be coupled to the first layer and define a microfluidic channel that establishes a fluid communication path between the first opening and the second opening. At least a portion of the second layer may be substantially opaque.Type: GrantFiled: October 3, 2019Date of Patent: May 23, 2023Assignee: Zoetis Services LLCInventors: Robert Justice Shartle, Sherb M. Edmondson, Jr., Bob Larson
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Patent number: 11628452Abstract: Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. An apparatus may include a first layer being substantially transparent. A second layer may be coupled to the first layer. The second layer may be substantially absorbent to infrared radiation. The second layer and the first layer may collectively define a set of wells. The first layer may define a base for each well of the set of wells. The second layer may define an opening for each well of the set of wells. At least one of the first layer and the second layer may define a sidewall for each well of the set of wells.Type: GrantFiled: August 22, 2019Date of Patent: April 18, 2023Assignee: Zoetis Services LLCInventors: Robert Justice Shartle, Gregory Trigub
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Patent number: 11370177Abstract: Described herein are various embodiments directed to rotor devices, methods, and systems. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. A method may include bonding a first layer and a second layer using two-shot injection molding. The first layer coupled to the second layer may collectively define a set of wells. The first layer may be substantially transparent. The second layer may define a channel. The second layer may be substantially absorbent to infrared radiation. A third layer may be bonded to the second layer using infrared radiation. The third layer may define an opening configured to receive a fluid. The third layer may be substantially transparent. The channel may establish a fluid communication path between the opening and the set of wells.Type: GrantFiled: August 22, 2019Date of Patent: June 28, 2022Assignee: Zoetis Services LLCInventors: Robert Justice Shartle, Gregory Trigub
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Patent number: 11369958Abstract: Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. An apparatus may include a first layer being substantially transparent. A second layer may be coupled to the first layer to collectively define a set of wells. The second layer may define a channel, and the second layer may be substantially absorbent to infrared radiation. A third layer may be coupled to the second layer. The third layer may define an opening configured to receive a fluid. The third layer may be substantially transparent. The channel may establish a fluid communication path between the opening and the set of wells.Type: GrantFiled: August 22, 2019Date of Patent: June 28, 2022Assignee: Zoetis Services LLCInventors: Robert Justice Shartle, Gregory Trigub
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Patent number: 11094050Abstract: Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. A method may include aligning an apparatus to an imaging device. The apparatus may include a set of wells defined by a first layer coupled to a second layer. The first layer may be substantially transparent to infrared radiation. The second layer may define a channel. The second layer may be substantially absorbent to the infrared radiation. The apparatus may further include a third layer coupled to the second layer and define an opening configured to receive a fluid. The third layer may be substantially transparent to the infrared radiation. A set of images of the apparatus may be generated using the imaging device. Bonding information may be generated based on the set of images.Type: GrantFiled: August 22, 2019Date of Patent: August 17, 2021Assignee: Zoetis Services LLCInventors: Robert Justice Shartle, Gregory Trigub
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Patent number: 10919039Abstract: A centrifugal rotor device includes a first chamber configured to hold a fluid, and a second chamber configured to receive the fluid from the first chamber. The centrifugal rotor device also includes a conduit coupled to the first chamber at a conduit inlet and coupled to the second chamber at a conduit outlet, the conduit configured to permit movement of the fluid from the first chamber to the second chamber. The conduit includes a first channel and a second channel formed adjacent to the first channel. The second channel is in fluid communication with the first channel and has a dimension smaller than the smallest dimension of the first channel. The conduit also includes one or more obstructive features present in the second channel configured to impede movement of the fluid in the second channel.Type: GrantFiled: December 20, 2018Date of Patent: February 16, 2021Assignee: ABAXIS, INC.Inventors: Gregory Trigub, Robert Justice Shartle, Warren Edward Farnam, III, Daniel E. Kuehner
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Publication number: 20200061637Abstract: Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. An apparatus may include a first layer being substantially transparent. A second layer may be coupled to the first layer. The second layer may be substantially absorbent to infrared radiation. The second layer and the first layer may collectively define a set of wells. The first layer may define a base for each well of the set of wells. The second layer may define an opening for each well of the set of wells. At least one of the first layer and the second layer may define a sidewall for each well of the set of wells.Type: ApplicationFiled: August 22, 2019Publication date: February 27, 2020Inventors: Robert Justice SHARTLE, Gregory TRIGUB
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Publication number: 20200065959Abstract: Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. A method may include aligning an apparatus to an imaging device. The apparatus may include a set of wells defined by a first layer coupled to a second layer. The first layer may be substantially transparent to infrared radiation. The second layer may define a channel. The second layer may be substantially absorbent to the infrared radiation. The apparatus may further include a third layer coupled to the second layer and define an opening configured to receive a fluid. The third layer may be substantially transparent to the infrared radiation. A set of images of the apparatus may be generated using the imaging device. Bonding information may be generated based on the set of images.Type: ApplicationFiled: August 22, 2019Publication date: February 27, 2020Inventors: Robert Justice SHARTLE, Gregory TRIGUB
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Publication number: 20200061613Abstract: Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. An apparatus may include a first layer being substantially transparent. A second layer may be coupled to the first layer to collectively define a set of wells. The second layer may define a channel, and the second layer may be substantially absorbent to infrared radiation. A third layer may be coupled to the second layer. The third layer may define an opening configured to receive a fluid. The third layer may be substantially transparent. The channel may establish a fluid communication path between the opening and the set of wells.Type: ApplicationFiled: August 22, 2019Publication date: February 27, 2020Inventors: Robert Justice SHARTLE, Gregory TRIGUB
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Publication number: 20200061930Abstract: Described herein are various embodiments directed to rotor devices, methods, and systems. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. A method may include bonding a first layer and a second layer using two-shot injection molding. The first layer coupled to the second layer may collectively define a set of wells. The first layer may be substantially transparent. The second layer may define a channel. The second layer may be substantially absorbent to infrared radiation. A third layer may be bonded to the second layer using infrared radiation. The third layer may define an opening configured to receive a fluid. The third layer may be substantially transparent. The channel may establish a fluid communication path between the opening and the set of wells.Type: ApplicationFiled: August 22, 2019Publication date: February 27, 2020Inventors: Robert Justice SHARTLE, Gregory TRIGUB
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Publication number: 20200030797Abstract: Described herein are various inventions and embodiments thereof, directed to systems, devices, and methods for analysis of a biofluid, as well as controlling a biofluid analysis system using a microfluidic device. Embodiments of biofluid analysis systems disclosed herein may provide analysis of a biofluid to identify and characterize one or more analytes. An apparatus may include a first layer defining a first opening and a second opening. The first layer may be substantially transparent. A second layer may be coupled to the first layer and define a microfluidic channel that establishes a fluid communication path between the first opening and the second opening. At least a portion of the second layer may be substantially opaque.Type: ApplicationFiled: October 3, 2019Publication date: January 30, 2020Inventors: Robert Justice SHARTLE, Sherb M. EDMONDSON,, Jr., Bob LARSON
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Publication number: 20190168214Abstract: A centrifugal rotor device includes a first chamber configured to hold a fluid, and a second chamber configured to receive the fluid from the first chamber. The centrifugal rotor device also includes a conduit coupled to the first chamber at a conduit inlet and coupled to the second chamber at a conduit outlet, the conduit configured to permit movement of the fluid from the first chamber to the second chamber. The conduit includes a first channel and a second channel formed adjacent to the first channel. The second channel is in fluid communication with the first channel and has a dimension smaller than the smallest dimension of the first channel. The conduit also includes one or more obstructive features present in the second channel configured to impede movement of the fluid in the second channel.Type: ApplicationFiled: December 20, 2018Publication date: June 6, 2019Inventors: Gregory TRIGUB, Robert Justice SHARTLE, Warren Edward FARNAM, III, Daniel E. KUEHNER
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Patent number: 7548772Abstract: A flexible diagnostic device has a measurement cell that is sandwiched between the conductive surfaces of two conductive-coated insulating layers. At least one of the conductive surfaces is scored with an insulating pattern, so that the flow of a conductive fluid sample into the cell can be monitored.Type: GrantFiled: May 2, 2006Date of Patent: June 16, 2009Assignee: Lifescan, Inc.Inventors: Robert Justice Shartle, Timothy J. Ohara, Mahyar Z. Kermani
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Patent number: 7050843Abstract: A flexible diagnostic device has a measurement cell that is sandwiched between the conductive surfaces of two conductive-coated insulating layers. At least one of the conductive surfaces is scored with an insulating pattern, so that the flow of a conductive fluid sample into the cell can be monitored.Type: GrantFiled: October 28, 2004Date of Patent: May 23, 2006Assignee: Lifescan, Inc.Inventors: Robert Justice Shartle, Timothy J. Ohara, Mahyar Z. Kermani
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Patent number: 7022286Abstract: A fluidic medical diagnostic device permits measurement of analyte concentration or a property of a biological fluid, particularly the coagulation time of blood. The device has at one end a sample port for introducing a sample and at the other end a bladder for drawing the sample to a measurement area. A channel carries the sample from the sample port to the measurement area, and a stop junction, between the measurement area and bladder, halts the sample flow. The desired measurement can be made by placing the device into a meter which measures a physical property of the sample—typically, optical transmittance—after it has interacted with a reagent in the measurement area.Type: GrantFiled: December 26, 2002Date of Patent: April 4, 2006Assignee: Lifescan, Inc.Inventors: John Lemke, Robert Justice Shartle, Victor Pan, Philip Cizdziel
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Patent number: 6908593Abstract: A medical diagnostic device for measuring an analyte concentration or property of a biological fluid includes capillary flow channels to convey a sample of the fluid from an inlet to a branching point, and then to a measurement area and, alternatively, through a bypass channel to an overflow region. A first stop junction stops fluid flow after it enters the measurement area. The bypass channel has a capillary dimension in at least one direction. A second stop junction, in the bypass channel, has boundary region that has a dimension that is greater in that direction and forms an angle that points toward the branching point. With this construction, the second stop junction initially prevents flow to the overflow region, but permits the flow after the measurement area is filled. The device is particularly suited for measuring coagulation time of blood.Type: GrantFiled: March 31, 2000Date of Patent: June 21, 2005Assignee: Lifescan, Inc.Inventor: Robert Justice Shartle
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Patent number: 6830934Abstract: A medical diagnostic device has a non-absorbent substrate that has a hydrophilic target area on which a reagent is deposited by non-impact printing of microdroplets. During deposition, the device is moved relative to the stream of microdroplets to form a substantially uniform reagent layer on the substrate. The device is particularly well adapted for measuring blood coagulation times. In a preferred embodiment, coagulation times are determined by monitoring the optical transmission of light through the target area as an applied blood sample interacts with the reagent.Type: GrantFiled: December 3, 1999Date of Patent: December 14, 2004Assignee: LifeScan, Inc.Inventors: Ian A. Harding, Robert Justice Shartle, Glenn Renowitzky, Lewis Leung
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Publication number: 20040109790Abstract: A fluidic medical diagnostic device-permits measurement of analyte concentration or a property of a biological fluid, particularly the coagulation time of blood. The device has at one end a sample port for introducing a sample and at the other end a bladder for drawing the sample to a measurement area. A channel carries the sample from the sample port to the measurement area, and a stop junction, between the measurement area and bladder, halts the sample flow. The desired measurement can be made by placing the device into a meter which measures a physical property of the sample—typically, optical transmittance—after it has interacted with a reagent in the measurement area.Type: ApplicationFiled: September 18, 2003Publication date: June 10, 2004Inventors: Robert Justice Shartle, Herbert Chow, Christa Hartmann
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Publication number: 20040067341Abstract: Devices for conducting electrical signals and methods for fabricating the subject devices are provided by the present invention. The subject devices are layered structures which include at least one textured conductive film, layer or surface designed to resist the effects of scratching of the material and thereby maintain the conductivity of the material. More specifically, the subject devices include thin metal films or metallized surfaces having peaks and valleys formed therein such that a scratch within the film or surface does not extend completely through to the bottom surface of the valley, thereby maintaining a conductive pathway through the film or surface.Type: ApplicationFiled: October 2, 2002Publication date: April 8, 2004Inventor: Robert Justice Shartle
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Publication number: 20040068165Abstract: A flexible diagnostic device has a measurement cell that is sandwiched between the conductive surfaces of two conductive-coated insulating layers. At least one of the conductive surfaces is scored with an insulating pattern, so that the flow of a conductive fluid sample into the cell can be monitored.Type: ApplicationFiled: October 3, 2003Publication date: April 8, 2004Inventors: Robert Justice Shartle, Timothy J. Ohara, Mahyar Z. Kermani