Patents by Inventor Robert K. Mansfield

Robert K. Mansfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMORPHIC FORM OF TG02 FOR TREATING CANCER
    Publication number: 20200262843
    Abstract: The present disclosure provides crystalline polymorphic forms of TG02 free base and TG02 acid addition salts, pharmaceutical compositions comprising crystalline polymorphic forms of TG02 free base and TG02 acid addition salts, and methods of treating cancer and other diseases in a patient with crystalline polymorphic forms of TG02 free base and TG02 acid addition salts.
    Type: Application
    Filed: January 24, 2020
    Publication date: August 20, 2020
    Inventors: Robert K. MANSFIELD, Tracy PARROT
  • Polymorphic form of TG02
    Patent number: 10544162
    Abstract: The present disclosure provides crystalline polymorphic forms of TG02 free base and TG02 acid addition salts, pharmaceutical compositions comprising crystalline polymorphic forms of TG02 free base and TG02 acid addition salts, and methods of treating cancer and other diseases in a patient with crystalline polymorphic forms of TG02 free base and TG02 acid addition salts.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: January 28, 2020
    Assignee: ADASTRA PHARMACEUTICALS, INC.
    Inventors: Robert K. Mansfield, Tracy Parrott
  • Polymorphic form of TG02
    Publication number: 20190055263
    Abstract: The present disclosure provides crystalline polymorphic forms of TG02 free base and TG02 acid addition salts, pharmaceutical compositions comprising crystalline polymorphic forms of TG02 free base and TG02 acid addition salts, and methods of treating cancer and other diseases in a patient with crystalline polymorphic forms of TG02 free base and TG02 acid addition salts.
    Type: Application
    Filed: August 17, 2018
    Publication date: February 21, 2019
    Inventors: Robert K. Mansfield, Tracy Parrott
  • Solid state forms of macrocyclic kinase inhibitors
    Patent number: 9120815
    Abstract: Provided herein are salt forms of macrocyclic protein kinase inhibitors, pharmaceutical compositions containing the same, methods of making and using these compounds and compositions to treat proliferative disease mediated by kinase activity.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: September 1, 2015
    Assignee: Tragara Pharmaceuticals, Inc.
    Inventors: Robert K. Mansfield, Tracy Lawhon, Brian Dymock
  • SOLID STATE FORMS OF MACROCYCLIC KINASE INHIBITORS
    Publication number: 20130150378
    Abstract: Provided herein are salt forms of macrocyclic protein kinase inhibitors, pharmaceutical compositions containing the same, methods of making and using these compounds and compositions to treat proliferative disease mediated by kinase activity.
    Type: Application
    Filed: February 4, 2011
    Publication date: June 13, 2013
    Inventors: Robert K. Mansfield, Tracy Lawhon, Brian Dymock
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER, TUMORS, AND TUMOR-RELATED DISORDERS
    Publication number: 20130084281
    Abstract: Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
    Type: Application
    Filed: June 21, 2012
    Publication date: April 4, 2013
    Applicant: Tragara Pharmaceuticals, Inc.
    Inventors: Thomas M. Estok, Sara L. Zaknoen, Robert K. Mansfield, Tracy Lawhon
  • Methods and compositions for the treatment of cancer, tumors, and tumor-related disorders
    Patent number: 8247423
    Abstract: Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: August 21, 2012
    Assignee: Tragara Pharmaceuticals, Inc.
    Inventors: Thomas M. Estok, Sara L. Zaknoen, Robert K. Mansfield, Tracy Lawhon
  • THERAPIES FOR TREATING CANCER USING COMBINATIONS OF COX-2 INHIBITORS AND ANTI-HER2(ERBB2) ANTIBODIES OR COMBINATIONS OF COX-2 INHIBITORS AND HER2(ERBB2) RECEPTOR TYROSINE KINASE INHIBITORS
    Publication number: 20120052061
    Abstract: Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
    Type: Application
    Filed: September 23, 2008
    Publication date: March 1, 2012
    Applicant: Tragara Pharmaceuticals Inc.
    Inventors: Thomas M. Estok, Sara L. Zaknoen, Robert K. Mansfield, Tracy Lawhon
  • THERAPIES FOR TREATING CANCER USING COMBINATIONS OF COX-2 INHIBITORS AND AROMATASE INHIBITORS OR COMBINATIONS OF COX-2 INHIBITORS AND ESTROGEN RECEPTOR ANTAGONISTS
    Publication number: 20120015919
    Abstract: Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
    Type: Application
    Filed: September 23, 2008
    Publication date: January 19, 2012
    Applicant: Tragara Pharmaceuticals, Inc.
    Inventors: Thomas M. Estok, Sara L. Zaknoen, Robert K. Mansfield, Tracy Lawhon
  • COMBINATION THERAPY FOR THE TREATMENT OF CANCER USING COX-2 INHIBITORS AND DUAL InHIBITORS OF EGFR [ErbB1] AND HER-2 [ErbB2]
    Publication number: 20110306572
    Abstract: Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
    Type: Application
    Filed: September 23, 2008
    Publication date: December 15, 2011
    Applicant: TRAGARA PHARMACEUTICALS, INC
    Inventors: Thomas M. Estok, Sara L. Zaknoen, Robert K. Mansfield
  • System and method for comprehensive management of company equity structures and related company documents with financial and human resource system integration
    Publication number: 20110106676
    Abstract: A system comprises business logic operable for managing and administering company entities, records, documents, equity instruments, and stakeholders, a database storing data associated with the business logic, integration logic operable to integrate the business logic and its associated data with existing enterprise systems and data associated therewith, and a graphical user interface presenting a hierarchical tree view of the company entities, records, documents, equity instruments, and stakeholders.
    Type: Application
    Filed: September 17, 2010
    Publication date: May 5, 2011
    Inventors: Andrew E. Levi, Bradley W. Bauer, Robert C. Woldberg, Robert K. Mansfield
  • ORAL PHARMACEUTICAL FORMULATIONS AND METHODS FOR PRODUCING AND USING SAME
    Publication number: 20100063020
    Abstract: Oral pharmaceutical formulations and methods of producing and using the same are described and claimed. The formulations are dispersions of phospholipids and one or more pharmacologically active compounds, In preferred embodiments, the pharmaceutically active compounds are ansamycins, pharmaceutically acceptable salts, or prodrugs thereof.
    Type: Application
    Filed: September 4, 2009
    Publication date: March 11, 2010
    Inventors: Robert K. Mansfield, Edgar H. Ulm, Gregg A. Timony
  • System and method for comprehensive management of company equity structures and related company documents withfinancial and human resource system integration
    Publication number: 20090293104
    Abstract: A system comprises business logic operable for managing and administering company entities, records, documents, equity instruments, and stakeholders, a database storing data associated with the business logic, integration logic operable to integrate the business logic and its associated data with existing enterprise systems and data associated therewith, and a graphical user interface presenting a hierarchical tree view of the company entities, records, documents, equity instruments, and stakeholders.
    Type: Application
    Filed: June 3, 2009
    Publication date: November 26, 2009
    Inventors: Andrew E. Levi, Bradley W. Bauer, Robert C. Woldberg, Robert K. Mansfield
  • PHOSPHOLIPID-BASED PHARMACEUTICAL FORMULATIONS AND METHODS FOR PRODUCING AND USING SAME
    Publication number: 20090238880
    Abstract: Pharmaceutical formulations and methods of producing and using the same are described and claimed. The formulations are dispersions of phospholipids and one or more pharmacologically active compounds, pharmaceutically acceptable salts thereof, or prodrugs thereof. In specific embodiments, the pharmaceutically active compounds are ansamycins and the overall formulation is substantially devoid of medium and long chain triglycerides.
    Type: Application
    Filed: February 12, 2009
    Publication date: September 24, 2009
    Inventors: Edgar H. Ulm, Robert K. Mansfield, Gregg A. Timony, Marcus F. Boehm
  • Methods and Compositions for the Treatment of Cancer, Tumors, and Tumor-Related Disorders
    Publication number: 20090017024
    Abstract: Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
    Type: Application
    Filed: July 11, 2008
    Publication date: January 15, 2009
    Applicant: Tragara Pharmaceuticals, Inc.
    Inventors: Thomas M. Estok, Sara L. Zaknoen, Robert K. Mansfield, Tracy Lawhon