Patents by Inventor Robert K. Suto

Robert K. Suto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pin1-modulating compounds and methods of use thereof
    Patent number: 8258099
    Abstract: The invention is directed to peptide modulators of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer or neurodegenerative disease.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: September 4, 2012
    Assignees: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V., Beth Israel Deaconess Medical Center, Inc., The Salk Institute for Biological Studies
    Inventors: Kun Ping Lu, Robert K. Suto, Janusz M. Sowadski, Gunter S. Fischer, Joseph P. Noel, Mark Verdecia
  • Pin1-Modulating Compounds and Methods of Use Thereof
    Publication number: 20080214470
    Abstract: The invention is directed to peptide modulators of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer or neurodegenerative disease.
    Type: Application
    Filed: July 15, 2005
    Publication date: September 4, 2008
    Applicants: VERNALIS PLC, BETH ISRAEL DEACONESS MEDICAL CENTER, THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
    Inventors: Kun Ping Lu, Robert K. Suto, Janusz M. Sowadski, Gunter S. Fischer, Joseph P. Noel, Mark Verdecia
  • Pin1-modulating compounds and methods of use thereof
    Publication number: 20040214872
    Abstract: The invention is directed to modulators, e.g., inhibitors, of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer.
    Type: Application
    Filed: March 3, 2003
    Publication date: October 28, 2004
    Applicant: Pintex Pharmaceuticals, Inc.
    Inventors: Robert K. Suto, Timothy D. McKee, Thomas Tibbitts, Janusz Sowadski
  • Pin1-modulating compounds and methods of use thereof
    Publication number: 20040180889
    Abstract: The invention is directed to modulators, e.g., inhibitors, of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer.
    Type: Application
    Filed: March 3, 2003
    Publication date: September 16, 2004
    Applicant: Pintex Pharmaceuticals, Inc.
    Inventors: Robert K. Suto, Timothy D. McKee
  • Methods for designing specific inhibitors for Pin1 proline isomerase and Pin1-related molecules
    Publication number: 20040176912
    Abstract: This invention relates to methods for designing specific inhbitors of Pin1/parvulin family of peptidyl-prolyl cis-trans isomerases, particularly Pin1 and Pin1-related proteins, through the use of the structure coordinates and atomic details elucidated from the crystal structures of a mutant of Pin1, R14A, and co-complexes of R14A with various inhibitors. The invention further relates to inhibitors of Pin1 and Pin1-related proteins that are useful for therapeutic treatement of various disorders, and methods of using Pin1 inhibitors in pharmaceutical compositions. The invention further relates to the crystal structures of Pin1R14A alone, and of Pin1R14A in co-complex with molecules that bind to Pin1.
    Type: Application
    Filed: March 3, 2003
    Publication date: September 9, 2004
    Applicant: Pintex Pharmaceuticals, Inc.
    Inventors: Janusz Sowadski, Robert K. Suto
  • Pin1-modulating compounds and methods of use thereof
    Publication number: 20040176372
    Abstract: The invention is directed to modulators, e.g, inhibitors, of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer.
    Type: Application
    Filed: March 3, 2003
    Publication date: September 9, 2004
    Applicant: Pintex Pharmaceuticals, Inc.
    Inventors: Robert K. Suto, Timothy D. McKee
  • Methods of treating Pin1 associated disorders
    Publication number: 20040176277
    Abstract: This invention pertains to methods of treating Pin1 associated disorders through the administration of inhibitors of the Pin1 isomerase activity.
    Type: Application
    Filed: March 3, 2003
    Publication date: September 9, 2004
    Applicant: Pintex Pharmaceuticals, Inc.
    Inventors: Janusz M. Sowadski, Robert K. Suto