Abstract: A shield for a syringe containing biohazardous material includes an elongate body comprising a compartment extending longitudinally therethrough from a body cold end to a body hot end, the compartment dimensioned to receive a syringe barrel; a cold end cover dimensioned to receive and enclose a syringe plunger extending beyond the body cold end, the cold end cover attachable at the body cold end for enclosing the compartment and the syringe plunger at the body cold end thereby to shieldingly contain the biohazardous material in the syringe at the body cold end; and a hot end cover attachable at the body hot end for at least enclosing the compartment at the body hot end thereby to shieldingly contain the biohazardous material in the syringe at the body hot end.

Abstract: A compression member for insertion into a pig for transporting a container of biohazardous materials includes a flange maintained in spaced relation with an annulus by pillars; and spaced apart pivotable grip components supported by the annulus and extending downwards from the annulus between respective ones of the pillars towards, but not into contact with, the flange, the pivotable grip components resiliently compressible inwardly against the container when the container is received within the compression member. In use, the compression member receives at least a closure portion of the container and, in turn, is itself received within a complementary annulus of the pig. When being received within the complementary annulus of the pig, the pivotable grip components are urged inwards towards the container thereby to grip the container and provide a spacer for between this portion of the container and the pig.

Abstract: A pig for transporting a container of biohazardous material, wherein the container comprises a bottle and a bottle closure. The pig includes a body comprising a compartment dimensioned to receive the container; a cap attachable to the body for closing the compartment thereby to shieldingly contain the biohazardous material in the container, the cap including: a collar sealingly engageable with the body and having an opening therethrough in communication with the compartment thereby to provide access to the bottle closure; a cap closure sealingly engageable within the opening of the collar to sealingly close the opening and cause the bottle closure to be gripped within the cap, wherein when the collar is disengaged from the body while the cap closure is engaged within the opening of the collar, the container remains gripped within the cap.

Abstract: Methods for preparing a personalized cancer vaccine and a method to train a machine-learning HLA-peptide presentation prediction model.

Abstract: Methods for preparing a personalized cancer vaccine and a method to train a machine-learning HLA-peptide presentation prediction model.

Abstract: A shield for a syringe containing biohazardous material includes an elongate body comprising a compartment extending longitudinally therethrough from a body cold end to a body hot end, the compartment dimensioned to receive a syringe barrel; a cold end cover dimensioned to receive and enclose a syringe plunger extending beyond the body cold end, the cold end cover attachable at the body cold end for enclosing the compartment and the syringe plunger at the body cold end thereby to shieldingly contain the biohazardous material in the syringe at the body cold end; and a hot end cover attachable at the body hot end for at least enclosing the compartment at the body hot end thereby to shieldingly contain the biohazardous material in the syringe at the body hot end.

Abstract: A compression member for insertion into a pig for transporting a container of biohazardous materials includes a flange maintained in spaced relation with an annulus by pillars; and spaced apart pivotable grip components supported by the annulus and extending downwards from the annulus between respective ones of the pillars towards, but not into contact with, the flange, the pivotable grip components resiliently compressible inwardly against the container when the container is received within the compression member. In use, the compression member receives at least a closure portion of the container and, in turn, is itself received within a complementary annulus of the pig. When being received within the complementary annulus of the pig, the pivotable grip components are urged inwards towards the container thereby to grip the container and provide a spacer for between this portion of the container and the pig.

Abstract: The present disclosure provides method for preparing a personalized cancer vaccine. The present disclosure also provides a method to train a machine-learning HLA-peptide presentation prediction model.

Abstract: A pig for transporting a container of biohazardous material, wherein the container comprises a bottle and a bottle closure. The pig includes a body comprising a compartment dimensioned to receive the container; a cap attachable to the body for closing the compartment thereby to shieldingly contain the biohazardous material in the container, the cap including: a collar sealingly engageable with the body and having an opening therethrough in communication with the compartment thereby to provide access to the bottle closure; a cap closure sealingly engageable within the opening of the collar to sealingly close the opening and cause the bottle closure to be gripped within the cap, wherein when the collar is disengaged from the body while the cap closure is engaged within the opening of the collar, the container remains gripped within the cap.

Abstract: Disclosed are methods for identifying high affinity adaptor molecules that bind to both a circulating antibody and a target molecule and redirect the specificity of the circulating antibody to the target molecule. Exemplary high affinity adaptor molecules are also provided.

Abstract: Disclosed are methods for identifying high affinity adaptor molecules that bind to both a circulating antibody and a target molecule and redirect the specificity of the circulating antibody to the target molecule. Exemplary high affinity adaptor molecules are also provided.

Abstract: A method of treating TNF? disorders is described, wherein the method comprises administering a low dose amount of a TNF? inhibitor.

Abstract: A method of treating TNF? disorders is described, wherein the method comprises administering a low dose amount of a TNF? inhibitor.

Abstract: Disclosed are methods for identifying high affinity adaptor molecules that bind to both a circulating antibody and a target molecule and redirect the specificity of the circulating antibody to the target molecule. Exemplary high affinity adaptor molecules are also provided.

Abstract: A method of treating TNF&agr; disorders is described, wherein the method comprises administering a low dose amount of a TNF&agr; inhibitor.