Abstract: A method and apparatus for the continuous deposition of RP HPLC eluent, from isocratic or gradient elutions, on to a MALDI target using a parallel sample desalting method, allows increased sensitivity of the MALDI sample by pre-concentration of the analyte, separation of interfering contaminants from the analyte and increased dynamic range of peptide abundance that can be analyzed. The parallel processing of sample material allows greater throughput than that of manual methods.

Abstract: The present invention includes a driven socket for a female threaded fastener formed from hexagonal steel stock or trilobe, D shaped stock, or round stock with other gripping or holding means. The driven socket also includes eight radial lobes located adjacent to one of the hexagon of equal length sides and equidistant from the center of the fastener for loosening and tightening the fastener. A method of the present invention includes the steps for removing or tightening a threaded fastener from a corresponding bolt comprising the steps of: positioning a socket over a washer-nut; positioning a key to align a locking ring having tabs into a slot in the fastener to hold the socket securely to the locking fastener; engaging a lobe on the fastener to place pressure on a leveraging portion of the socket; and wherein rotating the socket removes or tightens the fastener.

Abstract: A method and apparatus for the continuous deposition of RP HPLC eluent, from isocratic or gradient elutions, on to a MALDI target using a parallel sample desalting method, allows increased sensitivity of the MALDI sample by pre-concentration of the analyte, separation of interfering contaminants from the analyte and increased dynamic range of peptide abundance that can be analyzed. The parallel processing of sample material allows greater throughput than that of manual methods.

Abstract: A probe apparatus for aspirating a liquid sample from a container including a probe and a probe tip. The probe tip has a free end including a plurality of sharp points and cutting edges formed by the juncture of exposed surfaces. The exposed surfaces have a length and shape which promote liquid movement by surface tension forces along the exposed surfaces. A filter is secured to the end of the probe tip and a passageway for liquid extends through the probe and probe tip.