Patents by Inventor Robert Kingston

Robert Kingston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of factors that associate directly or indirectly with non-coding RNAS
    Patent number: 10273529
    Abstract: Methods and assays are provided for isolating factors including polypeptides, ribonucleic acids (RNAs) and polypeptide complexes that are associated with a target nucleic acid sequence. The target nucleic acid sequence may be comprised within chromatin. The methods are suitable for identification and characterisation of factors including non-coding RNAs (ncRNAs) that associate with specified genomic loci.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: April 30, 2019
    Assignee: THE GENERAL HOSPITAL CORPORATION
    Inventors: Robert Kingston, Matthew Simon, Jason Allen West
  • ISOLATION OF PROTEIN FACTORS THAT ASSOCIATE DIRECTLY OR INDIRECTLY WITH NUCLEIC ACIDS
    Publication number: 20150307939
    Abstract: Methods for isolating polypeptides and polypeptide complexes that are associated with a target nucleic acid sequence are provided.
    Type: Application
    Filed: June 17, 2015
    Publication date: October 29, 2015
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Robert KINGSTON, Jerome DEJARDIN
  • ISOLATION OF FACTORS THAT ASSOCIATE DIRECTLY OR INDIRECTLY WITH NON-CODING RNAS
    Publication number: 20150056615
    Abstract: Methods and assays are provided for isolating factors including polypeptides, ribonucleic acids (RNAs) and polypeptide complexes that are associated with a target nucleic acid sequence. The target nucleic acid sequence may be comprised within chromatin. The methods are suitable for identification and characterisation of factors including non-coding RNAs (ncRNAs) that associate with specified genomic loci.
    Type: Application
    Filed: August 20, 2012
    Publication date: February 26, 2015
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Robert Kingston, Matthew Simon, Jason Allen West
  • ISOLATION OF FACTORS THAT ASSOCIATE DIRECTLY OR INDIRECTLY WITH CHROMATIN
    Publication number: 20120040857
    Abstract: Methods for isolating non-coding nucleic acids that are associated with chromatin at a target genomic locus are provided.
    Type: Application
    Filed: February 12, 2010
    Publication date: February 16, 2012
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Robert Kingston, Jerome Dejardin, Matthew Simon
  • ISOLATION OF PROTEIN FACTORS THAT ASSOCIATE DIRECTLY OR INDIRECTLY WITH NUCLEIC ACIDS
    Publication number: 20110262908
    Abstract: Methods for isolating polypeptides and polypeptide complexes that are associated with a target nucleic acid sequence are provided. The methods comprise the steps of obtaining a sample that comprises a target nucleic acid sequence and one or more polypeptides or proteins associated with that target nucleic acid sequence; contacting the sample with at least one oligonucleotide probe that comprises a sequence that is complimentary to and capable of hybridising with at least a portion of the target nucleic acid sequence, wherein the oligonucleotide probe comprises at least one locked nucleic acid (LNA) nucleotide and wherein the oligonucleotide probe further comprises at least one affinity label (e.g.
    Type: Application
    Filed: August 20, 2008
    Publication date: October 27, 2011
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Robert Kingston, Jerome Dejardin