Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: Dynamic multi-network security controls are provided herein. A method can include receiving, via an internet protocol network, a report of malicious network traffic observed by first network equipment operating in a first communication network communicatively coupled to the internet protocol network, wherein the report indicates a second communication network, communicatively coupled to the internet protocol network and distinct from the first communication network, as an originating network of the malicious network traffic; in response to receiving the report, identifying second network equipment operating in the second communication network as a source of the malicious network traffic; and causing a control device associated with the second communication network to prevent the second network equipment from transmitting network traffic, comprising the malicious network traffic, outside of the second communication network via the internet protocol network for a defined time interval.