Abstract: A bowling glove includes a glove body including a palm portion configured to cover a palm of a wearer, and a protruding nub securably attachable to the palm portion of the glove body such that the location of the protruding nub relative to the palm portion of the glove body is selectively adjustable. The protruding nub is configured to protrude from the palm portion of the glove body, and the protruding nub is configured to be received by a bore of a bowling ball. A method of manufacturing the bowling glove and a method of fitting a bowling ball to the bowling glove are further described.

Abstract: A bowling glove includes a glove body including a palm portion configured to cover a palm of a wearer, and a protruding nub securably attachable to the palm portion of the glove body such that the location of the protruding nub relative to the palm portion of the glove body is selectively adjustable. The protruding nub is configured to protrude from the palm portion of the glove body, and the protruding nub is configured to be received by a bore of a bowling ball. A method of manufacturing the bowling glove and a method of fitting a bowling ball to the bowling glove are further described.

Abstract: The invention relates to a casing assembly for an axial compressor of a gas turbine engine, wherein the casing assembly comprises a compressor casing which has a plurality of annular casings which in the axial direction are mutually contiguous by way of screwless interfaces and which are connected to one another by a clamping force. It is provided that the casing assembly comprises a clamping spring which provides the clamping force for connecting the annular casings, wherein the clamping spring is disposed and positioned in such a manner that said clamping spring is not part of a load path of the gas turbine.

Abstract: A housing for a rotor of an engine is provided. The housing forms an interior space for accommodating the rotor that is defined by a housing wall and the housing wall (W) circumferentially surrounds the rotor that is accommodated inside the housing. The housing has at least one service opening which is provided in the housing wall for maintenance and/or repair work and through which the interior space is accessible from the outside. The service opening is provided in the area of two facing flange sections of the housing, wherein the service opening is closed by at least one closure part that is received at least partially inside a gap formed between the facing flange sections and fixated therein in a releasable manner.

Abstract: The present invention provides methods, compositions, and kits for detecting the presence or absence of target sequences in a sample, where the sample also contains interfering sequences that are similar or identical to the target sequences. In particular, the present invention provides blocker oligonucleotides that at least partially inhibit the formation of invasive cleavage structures with the interfering sequences but do not substantially inhibit the formation of invasive cleavage structures with the target sequences.

Abstract: The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.

Abstract: The present invention relates to compositions, methods, and kits for quantifying variations in gene copy number, e.g., of individual genes or of chromosomes or portions of chromosomes in an homogeneous reaction, without the need for target amplification, fragment size resolution, or microscopy.

Abstract: The present invention provides compositions and methods for the detection and characterization of mutations associated with cystic fibrosis. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of mutations in the CFTR gene associated with cystic fibrosis. The present invention also provides compositions, methods and kits for screening sets of CFTR alleles in a single reaction container.

Abstract: Reagents, methods and kits for the purification of DNA from biological materials are provided.

Abstract: The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of nucleic acid from various viruses in a sample.