Abstract: Systems and methods configured for estimating safety-related risks associated with adverse events and poor patient outcomes associated with the use of medical products and treatment (e.g., drugs, vaccines, medications, dietary supplements, and medical devices) are provided. More particularly, the present description relates to a method and system for estimating the downstream medical costs and therefore the risk (e.g., using a safety risk score, ranking, designation, estimate, or the like) associated with the use of an individual medical treatment.

Abstract: Certain embodiments described herein relate to systems and methods used to estimate safety-related risks associated with the use of medical products, treatments, and interventions (e.g., drugs, vaccines, medications, dietary supplements, and medical devices). More particularly, the present description relates to a method and system for estimating the risk (e.g., using a safety risk score, ranking, designation, estimate, or the like) associated with the use of an individual medical intervention.

Abstract: An improved differential gear mechanism is characterized by a lockout mechanism (63) operably associated with a flyweight mechanism (53) and including a lockout member (65, 101) positionable, in response to an input signal, in a normal condition and a lockout condition. In the normal condition, the lockout member (65, 101) permits a flyweight stop surface (57) to move from the retracted position to the extended position. In the lockout condition, the lockout member (65, 101) prevents the flyweight stop surface (57) from moving from the retracted position to the extended position.

Abstract: An improved differential gear mechanism is characterized by a lockout mechanism (129) operably associated with a latch member (119) that cooperates with a flyweight mechanism (53) to retard differentiating action in the differential gear mechanism. The lockout mechanism (129) includes a lockout member (131) positionable, in response to an input signal, in a normal condition and a lockout condition. In the normal condition, the lockout member (131) permits the latch member (119) to move freely between a locking position and an unlocking position. In the lockout condition, the lockout member (131) prevents the latch member (119) from moving into the locking position.

Abstract: A coupling device (11) and method of assembly, the device being of the type including a plenum member (17) disposed at one axial end of the coupling housing (13,15), the method comprising configuring the plenum member (17) such that each of the required features (55,57,61,66) is disposed circumferentially between an adjacent pair of fastener holes (18H). Next, the input ring gear (R) is installed about the housing (13,15) of the coupling device (11), from an axial end opposite said plenum member (17), into assembly position adjacent said flange portion (18). Each of a plurality (N) of fasteners (89) is inserted through one of the fastener holes (18H) and into initial threaded engagement with the input ring gear (R). Finally, by means of a fastener driver, all of the plurality (N) of fasteners (89) are driven into full threaded engagement, substantially simultaneously, with the input ring gear (R).

Abstract: A coupling device (11) of the type including a clutch assembly (29) actuation of which is responsive to fluid pressure in a clutch piston apply chamber (43), and a series of fluid passages (53,55,57,59) communicating the chamber to a control valve assembly (69). A housing (15) defines a hub portion (61) surrounded by a plenum member (17) carrying two high pressure seals (63;163). The housing is formed such that the outer surface (60) of the hub portion is free of graphite porosity, to improve the life of the seals. Preferably, each of the seals (63;163) has a height/width ratio selected to provide the desired radially inward sealing force, but wherein the seals are still able to be assembled within the respective seal cavities (73,75;173,175).

Abstract: A coupling device (11) and method of assembly, the device being of the type including a plenum member (17) disposed at one axial end of the coupling housing (13,15), the method comprising configuring the plenum member (17) such that each of the required features (55,57,61,66) is disposed circumferentially between an adjacent pair of fastener holes (18H). Next, the input ring gear (R) is installed about the housing (13,15) of the coupling device (11), from an axial end opposite said plenum member (17), into assembly position adjacent said flange portion (18). Each of a plurality (N) of fasteners (89) is inserted through one of the fastener holes (18H) and into initial threaded engagement with the input ring gear (R). Finally, by means of a fastener driver, all of the plurality (N) of fasteners (89) are driven into full threaded engagement, substantially simultaneously, with the input ring gear (R).