Patents by Inventor Robert L. Bratzler

Robert L. Bratzler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and products for enhancing immune responses using imidazoquinoline compounds
    Publication number: 20030139364
    Abstract: The invention involves administration of an imidazoquinoline agent in combination with another therapeutic agent. The combination of drugs may be administered in synergistic amounts or in various dosages or at various time schedules. The invention also relates to kits and compositions concerning the combination of drugs. The combinations can be used to enhance ADCC, stimulate immune responses and/or patient and treat certain disorders.
    Type: Application
    Filed: October 15, 2002
    Publication date: July 24, 2003
    Applicant: University of Iowa Research Foundation
    Inventors: Arthur M. Krieg, Christian Schetter, Robert L. Bratzler, Jorg Vollmer, Marion Jurk, Stefan Bauer
  • Immunostimulatory nucleic acids for the treatment of asthma and allergy
    Publication number: 20030087848
    Abstract: The invention involves administration of an immunostimulatory nucleic acid alone or in combination with an asthma/allergy medicament for the treatment or prevention of asthma and allergy in subjects. The combination of drugs are administered in synergistic amounts or in various dosages or at various time schedules. The invention also relates to kits and compositions concerning the combination of drugs.
    Type: Application
    Filed: February 2, 2001
    Publication date: May 8, 2003
    Inventors: Robert L. Bratzler, Deanna M. Petersen, Yves Fouron
  • Inhibition of angiogenesis by nucleic acids
    Publication number: 20030055014
    Abstract: The invention relates to methods and products for inhibiting angiogenesis. At least one antiangiogenic nucleic acid molecule is administered to a subject to prevent or treat unwanted angiogenesis. Non-nucleic acid antiangiogenic agents also can be administered.
    Type: Application
    Filed: December 14, 2001
    Publication date: March 20, 2003
    Inventor: Robert L. Bratzler
  • Nucleic acids for the prevention and treatment of gastric ulcers
    Publication number: 20020198165
    Abstract: The invention relates to methods and products for treating gastric ulcers. A nucleic acid and optionally an anti-ulcer agent are administered to a subject to prevent or treat gastric ulcer.
    Type: Application
    Filed: August 1, 2001
    Publication date: December 26, 2002
    Inventors: Robert L. Bratzler, Deanna M. Petersen
  • Immunostimulatory nucleic acids for the treatment of anemia, thrombocytopenia, and neutropenia
    Publication number: 20020165178
    Abstract: The invention involves administration of an immunostimulatory nucleic acid alone or in combination with an anemia, thrombocytopenia, or neutropenia medicament for the treatment or prevention of anemia, thrombocytopenia, and neutropenia in subjects. The agents in combination are administered in synergistic amounts or in various dosages or at various time schedules. The invention also relates to kits and compositions concerning the combination of immunostimulatory nucleic acids and anemia, thrombocytopenia, or neutropenia drugs.
    Type: Application
    Filed: June 28, 2001
    Publication date: November 7, 2002
    Inventors: Christian Schetter, Robert L. Bratzler, Deanna M. Petersen
  • Immunostimulatory nucleic acids and cancer medicament combination therapy for the treatment of cancer
    Publication number: 20020156033
    Abstract: The invention involves administration of an immunostimulatory nucleic acid in combination with a cancer medicament for the treatment or prevention of cancer in subjects. The combination of drugs are administered in synergistic amounts or in various dosages or at various time schedules. The invention also relates to kits and compositions concerning the combination of drugs.
    Type: Application
    Filed: March 5, 2001
    Publication date: October 24, 2002
    Inventors: Robert L. Bratzler, Deanna M. Petersen
  • Nucleic acids for the prevention and treatment of sexually transmitted diseases
    Publication number: 20020091097
    Abstract: The invention relates to methods and products for preventing and/or treating sexually transmitted diseases. A nucleic acid and optionally an anti-STD agent, a birth control agent and/or a birth control device are administered, optionally in the context of a sustained release device to a subject to prevent or treat STD.
    Type: Application
    Filed: September 7, 2001
    Publication date: July 11, 2002
    Inventors: Robert L. Bratzler, Deanna M. Petersen
  • Separation by carrier mediated transport
    Patent number: 5167824
    Abstract: Disclosed are processes and apparatus for separating a desired solute, such as an optically active isomer, from a complex mixture using carrier facilitated transport in an immobilized liquid membrane or carrier facilitated solvent extraction. The carrier is a binding protein selected and/or engineered to immunochemically reversibly bind to the solute and to have a significant solubility in the extracting solvent or immobilized liquid membrane.
    Type: Grant
    Filed: February 14, 1990
    Date of Patent: December 1, 1992
    Assignees: Creative BioMolecules, Inc., Sepracor, Inc.
    Inventors: Charles Cohen, Robert A. Dishman, James S. Huston, Robert L. Bratzler, David R. Dodds, Charles M. Zepp