Patents by Inventor Robert L. Camp

Robert L. Camp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8639450
    Abstract: Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: January 28, 2014
    Assignee: Yale University
    Inventors: David L. Rimm, Robert L. Camp
  • Patent number: 8497080
    Abstract: The method of the invention pertains to determining signal transduction activity in a tissue section by immunohistochemistry techniques. The expression level of the receptor of interest is determined as well as the expression levels of one or more effector molecules of the receptor signal transduction pathway. Furthermore a combined ratio of expression levels of effector molecules in subcellular compartments with the receptor expression was found to have prognostic significance.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: July 30, 2013
    Assignees: HistoRx, Inc., Yale University
    Inventors: Mark Gustavson, Jennifer Giltnane, Marisa P. Dolled-Filhart, Robert L. Camp, David L. Rimm
  • Patent number: 8367351
    Abstract: The method of the invention pertains to determining the signal transduction activity in a tissue section by immunohistochemistry techniques. The expression level of the receptor of interest is determined as well as the expression levels of one or more effector molecules of the receptor signal transduction pathway. Furthermore a combined ratio of expression levels of effector molecules in subcellular compartments with the receptor expression was found to have prognostic significance.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: February 5, 2013
    Assignees: Historx, Inc., Yale University
    Inventors: Mark Gustavson, Jennifer Giltnane, Marisa P. Dolled-Filhart, Robert L. Camp, David L. Rimm
  • Publication number: 20120329665
    Abstract: Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed.
    Type: Application
    Filed: May 2, 2012
    Publication date: December 27, 2012
    Inventors: David L. Rimm, Robert L. Camp
  • Publication number: 20120270239
    Abstract: The invention provides a method for determining the risk that a patient diagnosed with melanoma will develop a recurrence of melanoma comprising: a) determining the level of expression for each marker of a panel of markers, wherein the panel comprises activating transcription factor 2, p21WAF1, p16INK4A, ?-catenin, and fibronectin and the levels of expression are determined in compartments of interest in cells of interest in a tumor tissue sample from the patient; and b) determining whether an expression parameter for each marker in the tumor tissue sample is achieved by comparing the level of expression of each marker with a predetermined reference level associated with each marker; wherein the patient is at a low risk of developing a recurrence of melanoma if four or more of the expression parameters are achieved and wherein the patient is at a high risk of developing a recurrence of melanoma if three or fewer of the expression parameters are achieved.
    Type: Application
    Filed: October 29, 2010
    Publication date: October 25, 2012
    Inventors: David L. Rimm, Aaron J. Berger, Bonnie Rothberg, Robert L. Camp, Harriet Kluger
  • Patent number: 8185320
    Abstract: Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: May 22, 2012
    Assignee: Yale University
    Inventors: David L. Rimm, Robert L. Camp
  • Patent number: 8121794
    Abstract: Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: February 21, 2012
    Assignee: Yale University
    Inventors: David L. Rimm, Robert L. Camp
  • Patent number: 8036833
    Abstract: Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed.
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: October 11, 2011
    Assignee: Yale University
    Inventors: David L. Rimm, Robert L. Camp
  • Publication number: 20110081665
    Abstract: This invention provides a method of making a prognosis for a patient afflicted with a type of cancer such as colon cancer, based upon quantification of biomarkers such as thymidylate synthase in subcellular compartments.
    Type: Application
    Filed: March 10, 2010
    Publication date: April 7, 2011
    Inventors: David L. Rimm, Gregory Tedeschi, Robert L. Camp, Mark Gustavson
  • Patent number: 7873480
    Abstract: Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: January 18, 2011
    Assignee: Yale University
    Inventors: David L. Rimm, Robert L Camp
  • Patent number: 7709222
    Abstract: This invention provides a method of making a prognosis for a patient afflicted with a type of cancer such as colon cancer, based upon quantification of biomarkers such as thymidylate synthase in subcellular compartments.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: May 4, 2010
    Assignees: Yale University, Historx, Inc.
    Inventors: David L. Rimm, Gregory Tedeschi, Robert L. Camp, Mark Gustavson
  • Publication number: 20100062452
    Abstract: The method of the invention pertains to determining the signal transduction activity in a tissue section by immunohistochemistry techniques. The expression level of the receptor of interest is determined as well as the expression levels of one or more effector molecules of the receptor signal transduction pathway. Furthermore a combined ratio of expression levels of effector molecules in subcellular compartments with the receptor expression was found to have prognostic significance.
    Type: Application
    Filed: May 7, 2007
    Publication date: March 11, 2010
    Applicants: Yale University, HistoRx, Inc.
    Inventors: Mark Gustavson, Jennifer Giltnane, Marisa P. Dolled-Filhart, Robert L. Camp, David L. Rimm
  • Publication number: 20080153098
    Abstract: Provided are improved, quantitative methods for determining whether a subject is likely to respond to a breast cancer therapy, methods for selecting breast cancer therapies and methods for diagnosis and prognosis of breast cancer in subjects.
    Type: Application
    Filed: December 10, 2007
    Publication date: June 26, 2008
    Inventors: David L. Rimm, Gino Pereira, Malini Harigopal, Jennifer Gitnane, Marisa P. Dolled-Filhart, Robert L. Camp
  • Patent number: 7219016
    Abstract: Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed.
    Type: Grant
    Filed: February 1, 2002
    Date of Patent: May 15, 2007
    Assignee: Yale University
    Inventors: David L. Rimm, Robert L. Camp
  • Publication number: 20020177149
    Abstract: Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed.
    Type: Application
    Filed: February 1, 2002
    Publication date: November 28, 2002
    Inventors: David L. Rimm, Robert L. Camp