Abstract: A tissue sampling, collection, and processing system including a hand-supportable power-assisted tissue aspiration device having a cannula for aspirating fat tissue from a patient's body, and a multi-pack tissue sampling, processing and collecting device, installed between the tissue aspiration device and a vacuum source, and containing multiple tissue collection tubes for collection of aspirated fat tissue samples.

Abstract: Methods of treating type II diabetes, morbid obesity and metabolic syndrome in a human patient by performing mesenteric visceral fat aspiration in the bowel region of the patient using a powered twin-cannula fat aspiration instrument.

Abstract: Methods of tissue sampling, collection, in situ processing and re-injection using modular, disposable tissue aspiration, processing, collection and/or re-injection components.

Abstract: A twin-cannula fat tissue aspiration instrument system equipped with a hand-supportable fat aspiration instrument having a twin irrigating-type or tumescent-type electro-cauterizing cannula assembly with an inner cannula coupled to a cannula drive mechanism and having an inner aspiration aperture that is reciprocated within an outer cannula having an outer aspiration aperture and being connected to the front portion of the hand-supportable housing, so that said inner cannula reciprocates within said outer cannula when the cannula drive mechanism drives the inner cannula. An irrigation channel is formed along the outer cannula, and in fluid communication with an irrigation aperture formed at the distal portion of the outer cannula and proximate to the outer aspiration aperture.

Abstract: A tissue sampling, processing and collection device for connection in-line to a hand-held power-assisted tissue aspiration instrument and a vacuum source. The tissue sampling, processing and collection device includes a suction plate, mounted within a collection chamber, and having multiple hollow projections for supporting the open proximal ends of a plurality of tissue collection and processing tubes. Each of these tissue collection and processing tubes has micro-pores formed in the side walls thereof and its distal end opening is capped, thereby allowing fluid to flow and filter therethrough while the tissue collection and processing tube is mounted on the suction plate during tissue aspiration operations. The in-line tissue sampling, processing and collection device is provided with a knob for manually selecting the tissue collection and processing tube, into which a sampled of aspirated fat tissue to is be collected and processed in situ during tissue aspiration operations.

Abstract: A disposable cannula base device for insertion within a guide tube in a hand-supportable power-assisted tissue aspiration instrument including a hand-supportable housing with a rear portion, a cannula reciprocation mechanism, and a stationary tubing connector with a hollow tube section mounted within the rear portion of the hand-supportable housing. The disposable cannula base device includes a permanent magnetic ring supported on a hollow tube portion, between a set of fluid seals. The cannula reciprocation mechanism reciprocates the disposable cannula base device within the guide tube by exerting electromagnetic forces on the permanent magnetic ring.

Abstract: Tissue sampling, processing and injection syringe device and methods of filtering and concentrating cellular components of tissue sample in situ within the device.

Abstract: An irrigating twin-cannula aspiration system including a hand-supportable tissue aspiration instrument, having a twin cannula assembly, wherein an inner cannula having an aspiration aperture is mechanically reciprocated within a stationary outer cannula having an elongated aperture along which the aspiration aperture reciprocates, while the inner cannula is operably affixed to a vacuum source, and a controller controls synchronized pulsed tumescent infusion about the aspiration aperture during system operation.

Abstract: A method of and apparatus for photo-activating a collected sample of fat tissue including stem cells therein, contained in a tissue collection and processing device. The collected fat tissue sample including stem cells therein, is exposed to low levels of photo-active light energy while contained within the tissue collection and processing device. The tissue sample is photometrically-measured to determine the photo-activation index of the fat tissue sample. The Photo-active light energy emission is controlled to ensure optimized photo-activation, thereby providing the fat tissue sample with an improved capacity to bind free oxygen species in the fat tissue sample.

Abstract: A tissue aspiration instrumentation system including a hand-supportable tissue aspiration instrument and a cannula assembly. The hand-supportable tissue aspiration instrument has a hand-supportable housing with a stationary tubing connector provided at the rear of the housing and receiving a length of flexible tubing connected to a vacuum source. The cannula assembly is coupled to a cannula drive mechanism disposed within the hand-supportable housing and powered by an external power source (e.g. electrical power signals, pressurized air-streams, etc) so as to periodically exert forces on the cannula base portion along the longitudinal axis of the the cannula assembly (i.e. coaxially exerted on the cannula base portion).

Abstract: Methods of and apparatus for safely harvesting, processing (i.e. preparing), collecting and re-injecting adipose and other forms of tissue for immediate autologous tissue transplantation, explant culture endeavors or cell dissociations and the like.

Abstract: A method of and apparatus for safely removing visceral fatty tissue from the patient's mesentery and omentum is disclosed. In the preferred embodiment, the method involves using a novel minimally invasive or laparoscopic surgical procedure involving the inflation of the abdominal region with gas that creates a space between the wall of the abdomen and the organs inside. Using short incisions in the skin, narrow tubes are inserted through the abdominal wall so that a laparoscopically-guided electro-cauterizing and irrigating visceral fat aspiration instrument can be passed through the incision to perform the maneuvers necessary for the operation. Removal of visceral fat from the mesentery is observed directly on a video monitor, which receives its picture from a video camera attached to the laparoscope. Using this technique, it is now possible to safely remove visceral fat from the patient's mesentery to treat abdominal obesity, type II diabetes mellitus and/or metabolic syndrome in human patients.

Abstract: A method of and apparatus for safely removing visceral fatty tissue from the patient's mesentery is disclosed. In the preferred embodiment, the method involves using a novel minimally invasive or laparoscopic surgical procedure involving the inflation of the abdominal region with gas that creates a space between the wall of the abdomen and the organs inside. Using short incisions in the skin, narrow tubes are inserted through the abdominal wall so that a laparoscopically-guided electro-cauterizing and irrigating liposuction instrument can be passed through the incision to perform the maneuvers necessary for the operation. Removal of visceral fat from the mesentery is observed directly on a video monitor, which receives its picture from a video camera attached to the laparoscope. Using this technique, it is now possible to safely remove visceral fat from the patient's mesentery to treat abdominal obesity and/or metabolic syndrome in human patients.

Abstract: An apparatus is disclosed for mechanically-assisted liposuction treatment. The apparatus includes a hand-holdable housing, an electro-cauterizing cannula assembly, and a reciprocation mechanism. The hand-holdable housing has a cavity adaptable for receipt of a portion of the electro-cauterizing cannula assembly. The electro-cauterizing cannula assembly has a distal end and a proximal end and at least one aspiration aperture about the distal end. The reciprocation mechanism is disposed within the housing and is operably associated with either the cannula so that the cannulas can be selectively caused to reciprocate relative to the housing. As the cannula is caused to reciprocate relative to the housing, the aspiration aperture formed through the distal end of the cannula assembly is caused to undergo periodic displacement. The cannula assembly is releasably detachable from the hand-holdable housing to facilitate cleaning and sterilization of the cannula assembly and the housing.

Abstract: A multi-core connector system for interfacing first and second subsystems. The system includes a first multi-port connector provided on a first subsystem and supporting a first set of air-power supply-line connectors and electrical control signal connectors; and a second multi-port connector provided on a second subsystem and supporting a second set of air-power supply-line connectors and electrical control signal connectors. A first multi-port connector plug is adapted for connection to the first multi-port connector, and a second multi-port connector plug is adapted for connection to the second multi-port connector. A multi-core cable structure is provided for interconnecting the first and second multi-port connector plugs, and includes a plurality of air-supply tubes and a plurality of electrical control signal wires encased within a flexible casing.

Abstract: An air-powered tissue-aspiration instrument system, comprising an air-powered instrument having a hand-supportable housing supporting a curved dual cannula assembly having a curved hollow outer cannula and a flexible hollow inner cannula, provided with bipolar-type electro-cauterizing apparatus. A pair of RF-powered signals are supplied to the curved hollow outer cannula and flexible hollow inner cannula while the flexible hollow inner cannula is slidably supported within the curved hollow outer cannula and driven by an air-powered mechanism mounted within the hand-supportable housing so that the location of aspiration through outer and inner suction apertures is periodically displaced during tissue aspiration operations.

Abstract: A method and apparatus is disclosed for mechanically-assisted liposuction treatment. The apparatus includes a hand-holdable housing, an electro-cauterizing dual cannula assembly, and a reciprocation mechanism. The hand-holdable housing has a cavity adaptable for receipt of the electro-cauterizing cannula assembly. The electro-cauterizing cannula assembly has a distal end and a proximal end and at least one aspiration aperture about the distal end. The reciprocation mechanism is disposed within the housing and is operably associated with the inner cannula so that the inner cannula can be selectively caused to reciprocate relative to the stationary outer cannula mounted to the hand-supportable housing. As the inner cannula is caused to reciprocate relative to the housing, the aspiration aperture formed through the distal end of the cannula assembly is caused to undergo periodic displacement.

Abstract: An electro-cauterizing cannula assembly for use in a power-assisted liposuction instrument having a hand-holdable housing and a mechanism for reciprocating the cannula assembly. The electro-cauterizing cannula assembly includes an inner and an outer cannula, each having a distal and proximal end and at least one aspiration aperture about the distal end. The inner cannula is disposed within the outer cannula and the inner and outer aspiration apertures are in at least partial registration to form an effective aspiration aperture. During aspiration of tissue, high-voltage RF power signals are supplied to the inner and outer cannulas to effect hemostasis about the reciprocating aspiration aperture. Such hemostasis is achieved by causing protein molecules within aspirated tissue to coagulate in response to the high-voltage RF signals being supplied across the reciprocating cannulas. The cannula assembly is releasably detachable from the hand-holdable housing to facilitate cleaning and sterilization of the same.

Abstract: A method and apparatus is disclosed for mechanically-assisted liposuction treatment. The apparatus includes a hand-holdable housing, an electro-cauterizing cannula assembly, and a reciprocation mechanism. The hand-holdable housing has a cavity adaptable for receipt of a portion of the electro-cauterizing cannula assembly. The electro-cauterizing cannula assembly has a distal end and a proximal end and at least one aspiration aperture about the distal end. The reciprocation mechanism is disposed within the housing and is operably associated with either the cannula so that the cannulas can be selectively caused to reciprocate relative to the housing. As the cannula is caused to reciprocate relative to the housing, the aspiration aperture formed through the distal end of the cannula assembly is caused to undergo periodic displacement.

Abstract: A method and apparatus is disclosed for mechanically-assisted liposuction treatment. The apparatus includes a hand-holdable housing, an electro-cauterizing cannula assembly, and a reciprocation mechanism. The hand-holdable housing has a cavity adaptable for receipt of a portion of the electro-cauterizing cannula assembly. The electro-cauterizing cannula assembly includes an inner cannula and an outer cannula, each having a distal end and a proximal end and at least one aspiration aperture about the distal end. The inner cannula is disposed within the outer cannula and the inner and outer aspiration apertures are in at least partial registration to form an effective aspiration aperture. The reciprocation mechanism is disposed within the housing and is operably associated with either the inner or outer cannula so that one of the cannulas can be selectively caused to reciprocate relative to the housing while the other is stationarily disposed relative to the housing.