Patents by Inventor Robert L. Dedrick

Robert L. Dedrick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5720720
    Abstract: A method of high-flow microinfusion which provides convection-enhanced delivery of agents into the brain and other solid tissue structures. The method involves positioning the tip of an infusion catheter within a tissue structure and supplying an agent through the catheter while maintaining a pressure gradient from the tip of the catheter during infusion. Agent delivery rates of 0.5 to 15.0 .mu.l/min have been used experimentally with infusion distances greater than 1 cm from the delivery source. The method can be used to delivery various drugs, protein toxins, antibodies for treatment or imaging, proteins in enzyme replacement therapy, growth factors in the treatment of various neurodegenerative disorders and viruses and gene therapy. An infusion catheter developed for the high-flow microinfusion includes a plurality of elongated slits adjacent a tapered portion of the catheter which are parallel to the axis of the catheter and spaced symmetrically about the circumference thereof.
    Type: Grant
    Filed: March 15, 1996
    Date of Patent: February 24, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Douglas W. Laske, Edward H. Oldfield, Richard Hunt Bobo, Robert L. Dedrick, Paul F. Morrison
  • Patent number: 3946734
    Abstract: The subject invention is directed to an apparatus which selectively contr the rate with which a drug contained therein is released to surrounding tissue. Moreover, the subject invention is directed to process for controlling said release which comprises sealing the end of a suitable vessel with a non-porous material, inserting into said vessel a suitable medicament, and sealing the opposite end thereof with a porous neutral hydrogel through which naturally occuring materials can diffuse and further through which said medicament may diffuse.
    Type: Grant
    Filed: February 19, 1975
    Date of Patent: March 30, 1976
    Assignee: The United States of America as represented by the Secretary of State
    Inventors: Robert L. Dedrick, Robert J. Lutz, Daniel S. Zaharko
  • Patent number: D248713
    Type: Grant
    Filed: October 26, 1976
    Date of Patent: August 1, 1978
    Inventor: Robert L. Dedrick
  • Patent number: D248714
    Type: Grant
    Filed: November 29, 1976
    Date of Patent: August 1, 1978
    Inventor: Robert L. Dedrick