Patents by Inventor Robert L. Galloway

Robert L. Galloway has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200229968
    Abstract: A drug delivery device includes a catheter; a retention cap attached to an end of the catheter, having an operably openable surface; a flexible membrane having a rim securely connected to an inner surface of the catheter to define a first volume and a second volume therein, such that the second volume is substantially the same as a desired drug volume; and a pressurizable member coupled to the catheter. In use, the desired drug volume is preloaded into the second volume of the catheter that in turn is slided into a guidance device, when the guidance device is placed in a target, the pressurizable member applies a pressure into the first volume to exert a force upon the flexible membrane to operably squeeze the second volume, which in turn pressurizes the operably openable surface of the retention cap to open, thereby unloading the desired drug volume into the target.
    Type: Application
    Filed: October 24, 2016
    Publication date: July 23, 2020
    Inventor: Robert L. Galloway
  • Patent number: 8768022
    Abstract: A method and system of compensation for intra-operative organ shift of a living subject usable in image guide surgery. In one embodiment, the method includes the steps of generating a first geometric surface of the organ of the living subject from intra-operatively acquired images of the organ of the living subject, constructing an atlas of organ deformations of the living subject from pre-operatively acquired organ images from the pre-operatively acquired organ images, generating a second geometric surface of the organ from the atlas of organ deformations, aligning the second geometric surface of the organ to the first geometric surface of the organ of the living subject to determine at least one difference between a point of the first geometric surface and a corresponding point of the second geometric surface of the organ of the living subject, which is related to organ shift, and compensating for the intra-operative organ shift.
    Type: Grant
    Filed: November 1, 2012
    Date of Patent: July 1, 2014
    Assignee: Vanderbilt University
    Inventors: Michael I. Miga, Logan W. Clements, Robert L. Galloway
  • Patent number: 8403828
    Abstract: A flexible endoscope for ophthalmic orbital surgery includes a flexible probe housing having a proximal end, a distal end and a lumen extending between the proximal end and the distal end. The endoscope also includes an image fiber disposed in the lumen that communicates image information from the distal end of the flexible probe, a purge fluid/gas port disposed at the proximal end of the flexible probe that accepts purge fluid/gas and a purge fluid/gas conduit disposed in the lumen and in fluid communication with the purge fluid/gas port. The fluid/gas conduit delivers purge fluid/gas to the distal end of the endoscope. The endoscope also includes an access conduit disposed in the lumen that receives one of an ablation instrument, a coagulating instrument and a medication delivery instrument.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: March 26, 2013
    Assignee: Vanderbilt University
    Inventors: Louise A. Mawn, Robert L. Galloway, Jr.
  • Patent number: 8358818
    Abstract: A method and system of compensation for intra-operative organ shift of a living subject usable in image guide surgery. In one embodiment, the method includes the steps of generating a first geometric surface of the organ of the living subject from intra-operatively acquired images of the organ of the living subject, constructing an atlas of organ deformations of the living subject from pre-operatively acquired organ images from the pre-operatively acquired organ images, generating a second geometric surface of the organ from the atlas of organ deformations, aligning the second geometric surface of the organ to the first geometric surface of the organ of the living subject to determine at least one difference between a point of the first geometric surface and a corresponding point of the second geometric surface of the organ of the living subject, which is related to organ shift, and compensating for the intra-operative organ shift.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: January 22, 2013
    Assignee: Vanderbilt University
    Inventors: Michael I. Miga, Logan W. Clements, Robert L Galloway, Jr.
  • Publication number: 20080123927
    Abstract: A method and system of compensation for intra-operative organ shift of a living subject usable in image guide surgery. In one embodiment, the method includes the steps of generating a first geometric surface of the organ of the living subject from intra-operatively acquired images of the organ of the living subject, constructing an atlas of organ deformations of the living subject from pre-operatively acquired organ images from the pre-operatively acquired organ images, generating a second geometric surface of the organ from the atlas of organ deformations, aligning the second geometric surface of the organ to the first geometric surface of the organ of the living subject to determine at least one difference between a point of the first geometric surface and a corresponding point of the second geometric surface of the organ of the living subject, which is related to organ shift, and compensating for the intra-operative organ shift.
    Type: Application
    Filed: November 15, 2007
    Publication date: May 29, 2008
    Applicant: Vanderbilt University
    Inventors: Michael I. Miga, Logan W. Clements, Robert L. Galloway
  • Patent number: 7072707
    Abstract: A method and apparatus for collecting and processing physical space data used while performing image-guided surgery is disclosed. Physical space data is collected by probing physical surface points of surgically exposed tissue. The physical space data provides three-dimensional (3-D) coordinates for each of the physical surface points. Based on the physical space data collected, point-based registrations used to indicate surgical position in both image space and physical space are determined. In one embodiment, the surface of surgically exposed tissue of a living patient is illuminated with laser light. Light reflected from the illuminated surface of the exposed tissue is received and analyzed. In another embodiment, one or more magnetic fields of known shape and size are established in the proximity of the exposed tissue. Data associated with the strength of the magnetic fields is acquired and analyzed.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: July 4, 2006
    Assignee: Vanderbilt University
    Inventors: Robert L. Galloway, Jr., William C. Chapman, James D. Stefansic, Alan J. Herline, Michael I. Miga, David M. Cash, Tuhin K. Sinha
  • Publication number: 20040019274
    Abstract: A method and apparatus for collecting and processing physical space data used while performing image-guided surgery is disclosed. Physical space data is collected by probing physical surface points of surgically exposed tissue. The physical space data provides three-dimensional (3-D) coordinates for each of the physical surface points. Based on the physical space data collected, point-based registrations used to indicate surgical position in both image space and physical space are determined. In one embodiment, the surface of surgically exposed tissue of a living patient is illuminated with laser light. Light reflected from the illuminated surface of the exposed tissue is received and analyzed. In another embodiment, one or more magnetic fields of known shape and size are established in the proximity of the exposed tissue. Data associated with the strength of the magnetic fields is acquired and analyzed.
    Type: Application
    Filed: April 16, 2003
    Publication date: January 29, 2004
    Applicant: Vanderbilt University
    Inventors: Robert L. Galloway, William C. Chapman, James D. Stefansic, Alan J. Herline, Michael I. Miga, David M. Cash, Tuhin K. Sinha
  • Patent number: 6584339
    Abstract: A method and apparatus for collecting and processing physical space data used while performing image-guided surgery is disclosed. Physical space data is collected by probing physical surface points of surgically exposed tissue. The physical space data provides three-dimensional (3-D) coordinates for each of the physical surface points. Based on the physical space data collected, point-based registrations used to indicate surgical position in both image space and physical space are determined. The registrations are used to map into image space, image data describing the physical space of an ablative instrument used to perform the image-guided surgery, an ablation zone of the instrument, the surgically exposed tissue, and a particular portion of the tissue to be resected or ablated. The image data is updated on a periodic basis.
    Type: Grant
    Filed: June 27, 2001
    Date of Patent: June 24, 2003
    Assignee: Vanderbilt University
    Inventors: Robert L. Galloway, Jr., William C. Chapman, James D. Stefansic, Alan J. Herline, Candice D. Pinson
  • Publication number: 20030000535
    Abstract: A method and apparatus for collecting and processing physical space data used while performing image-guided surgery is disclosed. Physical space data is collected by probing physical surface points of surgically exposed tissue. The physical space data provides three-dimensional (3-D) coordinates for each of the physical surface points. Based on the physical space data collected, point-based registrations used to indicate surgical position in both image space and physical space are determined. The registrations are used to map into image space, image data describing the physical space of an ablative instrument used to perform the image-guided surgery, an ablation zone of the instrument, the surgically exposed tissue, and a particular portion of the tissue to be resected or ablated. The image data is updated on a periodic basis.
    Type: Application
    Filed: June 27, 2001
    Publication date: January 2, 2003
    Applicant: Vanderbilt University
    Inventors: Robert L. Galloway, William C. Chapman, James D. Stefansic, Alan J. Herline, Candice D. Pinson
  • Patent number: 6106464
    Abstract: An A-mode ultrasound transducer is tracked in three-dimensions by an optical position tracking system as the transducer is scanned over the skin to generate measurements of bone surface distance from the transducer. A processor correlates the ultrasound data with position and orientation data to generate a three-dimensional physical space model of the bone surface which is registered with an image space model of the bone surface generated from a tomographic image to produce an alignment of the two models. The ultrasound transducer is replaced by an instrument which is also optically tracked. The alignment is used to translate instrument position in physical space to a position in image space for generation on a monitor of a composite display of the instrument and the tomographic image. This composite display can be used to guide positioning and orienting the instrument in physical space with respect to sites of interest observed in the tomographic image on the display.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: August 22, 2000
    Assignee: Vanderbilt University
    Inventors: Wayne A. Bass, Robert L. Galloway, Jr., Calvin R. Maurer, Jr., Robert J. Maciunas
  • Patent number: 5394875
    Abstract: In a coordinate system defined by a coordinate space digitizer, the location of an implanted symmetric object may automatically be determined based on differences between the characteristic acoustic impedances of at least a portion of an implanted object and one or more materials surrounding that object. An A-mode ultrasound transducer may be attached to a coordinate space digitizer or pointing device such that an attached computer tracks the position and orientation of the ultrasound transducer. The reflected radio-frequency (rf) ultrasound signals may automatically be analyzed along with the transducer position and orientation corresponding to each received rf signal to detect the position of the implanted object. The time delay between received ultrasound echoes is used to compute the depth of the object from the transducer. This allows for an accurate determination of the three-dimensional coordinates of the implanted object.
    Type: Grant
    Filed: October 21, 1993
    Date of Patent: March 7, 1995
    Inventors: Judith T. Lewis, Robert L. Galloway, Jr.
  • Patent number: 5230338
    Abstract: An interactive system for guiding the use of a surgical tool uses at least one imaging technique, such as CT scanning. A mechanical arm has a fixed base at a first end and a tool holder that holds the surgical tool at a second end. A display displays one or more images from the image space of a patient's anatomy. A computer is coupled to the display and the mechanical arm. The computer tracks the location of the surgical tool through physical space, performs a transforming rotation of the physical space to the image space, and causes the display to display the location of the surgical tool within the image space.
    Type: Grant
    Filed: April 22, 1992
    Date of Patent: July 27, 1993
    Inventors: George S. Allen, Robert L. Galloway, Jr., Robert J. Maciunas, Charles A. Edwards, II, Martin R. Zink
  • Patent number: 5142930
    Abstract: An interactive system for guiding the use of a surgical tool uses at least one imaging technique, such as CT scanning. A mechanical arm has a fixed base at a first end and a tool holder that holds the surgical tool at a second end. A display displays one or more images from the image space of a patient's anatomy. A computer is coupled to the display and the mechanical arm. The computer tracks the location of the surgical tool through physical space, performs a transforming rotation of the physical space to the image space, and causes the display to display the location of the surgical tool within the image space.
    Type: Grant
    Filed: March 29, 1991
    Date of Patent: September 1, 1992
    Inventors: George S. Allen, Robert L. Galloway, Jr., Robert J. Maciunas, Charles A. Edwards, II, Martin R. Zink
  • Patent number: 4874949
    Abstract: Infrared sensitive indicator-dilution tracer concentration, specifically, 1,2 propanediol, can be optically measured in blood drawn from the systemic arterial system to indicate lung vascular function and transcapillary transport, i.e. pulmonary blood flow, extravascular lung water, transcapillary permeability-surface area, fluid filtration coefficients, etc. that may be helpful in diagnosing lung diseases, particularly Adult Respiratory Distress Syndrome (ARDS).
    Type: Grant
    Filed: September 14, 1987
    Date of Patent: October 17, 1989
    Assignee: Vanderbilt University
    Inventors: Thomas R. Harris, Robert L. Galloway, Jr.
  • Patent number: 4271865
    Abstract: A dry break coupling for connecting a pair of fluid conduits includes first and second housings adapted for connection to the respective conduits. The first housing includes a piston supported for axial sliding movement between a first position wherein fluid flow through the first housing is blocked and a second position wherein fluid is free to flow through the first housing. The second housing includes a poppet supported for axial movement between a first position wherein fluid flow through the second housing is blocked and a second position wherein fluid is free to flow through the second housing. A handle is provided on the first housing for moving the piston between the first and second positions therefor and the poppet is engaged by the piston and moved to its second position in response to axial movement of the piston from the first to the second position therefor.
    Type: Grant
    Filed: May 14, 1979
    Date of Patent: June 9, 1981
    Inventors: Robert L. Galloway, Charles R. Galloway