Abstract: This invention relates to comfortable ophthalmic devices and methods of producing such devices.

Abstract: CB-0406 choline salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.

Abstract: CB-0406 tromethamine salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.

Abstract: Various formulations of an alkaloid-containing topical analgesic involve extracting alkaloids from herbal material, infusing a carrier oil, and applying secondary ingredients to improve the formulation's therapeutic efficacy. Suitable herbal sources include, but are not limited to, Mitragyna speciosa, Rauwolfia serpentina, Sceletium tortuosum, Harpagophytum procumbens, Picralima natilda, Sceletium tortuosum, Combretum quadrangulare, Corydalis yanhusuo, Lactuca virosa, and/or Magnolia officinalis. Preferably, alcohol extractions of pre-frozen herbal material were vacuum reduced and the resulting alkaloid extraction was infused into an oil and combined with secondary ingredients, such as alkaloid potentiators, dermal absorption enhancers, anti-inflammation agents, brightening agents, neuropathic pain relief agents, and spasm relief agents.

Abstract: A physical layer network interface module (PHY-NIM) adaptation system provides a PHY-NIM device and an attachable media access control (MAC) device. The PHY-NIM device interconnects with the attachable MAC device and the attachable MAC device interconnects to a network appliance to provide at least one of network switch capabilities and MAC device capabilities for use by the network appliance. The PHY-NIM device interconnects directly to the network appliance where the network appliance has at least one of an internal network switch and an internal MAC device in a southbridge input/output (I/O) interface chip of the network appliance.

Abstract: A physical layer network interface module (PHY-NIM) adaptation system provides a PHY-NIM device and an attachable media access control (MAC) device. The PHY-NIM device interconnects with the attachable MAC device and the attachable MAC device interconnects to a network appliance to provide at least one of network switch capabilities and MAC device capabilities for use by the network appliance. The PHY-NIM device interconnects directly to the network appliance where the network appliance has at least one of an internal network switch and an internal MAC device in a southbridge input/output (I/O) interface chip of the network appliance.

Abstract: A physical layer network interface module (PHY-NIM) adaptation system provides a PHY-NIM device and an attachable media access control (MAC) device. The PHY-NIM device interconnects with the attachable MAC device and the attachable MAC device interconnects to a network appliance where the network appliance does not have at least one of an internal network switch and a MAC device in a southbridge input/output (I/O) interface chip of the network appliance. The PHY-NIM device interconnects directly to the network appliance without the attachable MAC device where the network appliance has at least one of the internal network switch and the MAC device in the southbridge I/O interface chip of the network appliance.

Abstract: Treatment of severe hyperlipidemia by administration of (R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid or a salt thereof in combination with a PCSK9 inhibitor.

Abstract: A physical layer network interface module (PHY-NIM) adaptation system provides a PHY-NIM device and an attachable media access control (MAC) device. The PHY-NIM device interconnects with the attachable MAC device and the attachable MAC device interconnects to a network appliance where the network appliance does not have at least one of an internal network switch and a MAC device in a southbridge input/output (I/O) interface chip of the network appliance. The PHY-NIM device interconnects directly to the network appliance without the attachable MAC device where the network appliance has at least one of the internal network switch and the MAC device in the southbridge I/O interface chip of the network appliance.

Abstract: Treatment of severe hypertriglyceridemia, such as Type I or Type V hyperlipoproteinemia, by therapy with MBX-8025 or an MBX-8025 salt, alone or in combination with one or more of a fibrate, niacin, and an omega-3 fatty acid, optionally accompanied by apheresis.

Abstract: Treatment of homozygous familial hypercholesterolemia by administration of (R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid or a salt thereof, optionally in combination with an MTP inhibitor, an apoB-100 synthesis inhibitor, or a PCSK9 inhibitor.

Abstract: Systems and methods for selecting, sequencing, and presenting traffic events to viewers. This may involve using a prioritizing scheme that estimates the proximity or relevance of the event to the viewers by associating the event with a geographic zone and the viewer with a localized service area served by a particular distribution points of the television content distribution system. In some cases, for each localized service area, zones are given priority values that are used when prioritizing the relevance of traffic events associated with those zones. For viewers in a given localized service area, a first zone may have a higher priority than a second zone, such that in prioritizing traffic events, events associated with the first zone are given a higher priority than events occurring in the second zone. Different zone priority schemes may be associated with a given localized service area at different times of day, week, or year.

Abstract: A beacon light member including a housing configured to be attached to a base member of a beacon light, the base member of the beacon light configured to utilize an incandescent light source. A power supply contained in the housing is configured to electrically connect to a power point in the base member. At least one light emitting diode (LED) light source is contained in the housing. A beacon light including a first base member, a second member, and at least one incandescent light source can also be retrofit. Under the retrofitting method, the at least one incandescent light source is removed, the second member is removed, and the second member is replaced with a beacon light module including at least one light emitting diode (LED) light source.

Abstract: A beacon light member including a housing configured to be attached to a base member of a beacon light, the base member of the beacon light configured to utilize an incandescent light source. A power supply contained in the housing is configured to electrically connect to a power point in the base member. At least one light emitting diode (LED) light source is contained in the housing. A beacon light including a first base member, a second member, and at least one incandescent light source can also be retrofit. Under the retrofitting method, the at least one incandescent light source is removed, the second member is removed, and the second member is replaced with a beacon light module including at least one light emitting diode (LED) light source.

Abstract: A light, such as for an airport taxiway, in which a base includes a light source which outputs light. The light source may be an LED (light emitting diode) light source which is highly energy efficient and which has a long life. A light guide receives and guides light output from the light source. The light guide further extends out from the light source. A reflector is positioned in the light guide and reflects the light guided through the light guide to provide the appropriate illumination.

Abstract: A beacon lamp which may find use in and around airports, communication towers, etc. The beacon lamp includes a plurality of light emitting diodes (LEDs) its as light source. The plurality of LEDs can be mounted on an LED module which is in turn secured to a base. A transparent outer cover is provided to cover the plurality of LEDs. The LED module can include heat fins to enhance heat sinking properties. The outer cover and base can also include portions to improve free air convection to also improve heat sinking properties. The LEDs may be connected in parallel to provide redundancy in the event that certain LEDs burn out. The beacon lamp is also structured to allow the outer cover to be easily removed from the base to access the LED modules, to allow easy relamping of the beacon lamp.

Abstract: A light, such as for an airport taxiway, in which a base includes a light source which outputs light. The light source may be an LED (light emitting diode) light source which is highly energy efficient and which has a long life. A light guide receives and guides light output from the light source. The light guide further extends out from the light source. A reflector is positioned in the light guide and reflects the light guided through the light guide to provide the appropriate illumination.

Abstract: A snowmobile ski-type runner braking system provides a braking "claw" at the trailing end of each snowmobile ski-type runner that can be activated by the operator from his console to pivot downward into digging engagement with the snow to help brake the snowmobile. The claws are activated in unison so that balanced braking force is applied to each trailing ski end on both sides of the snowmobile. Even with the claws extended into their digging mode, the operator can still steer by turning the skis. Each claw can be actuated by an electric motor and power screw mechanism mounted on the runner. Alternately, each claw can be actuated by a hydraulic piston/cylinder mechanism mounted on the runner.

Abstract: An all-terrain vehicle enclosure for simultaneously shielding a driver and a driver's all-terrain vehicle from adverse weather conditions and terrain hazards comprises a rigid frame having an open central portion for holding a driver and an all-terrain vehicle therein and a peripheral skeletal portion therearound; a rigid skin secured over the skeletal portion of the frame to define a body, the body further having at least one door aperture and at least one window aperture disposed thereon with the door aperture allowing a driver access therein; and a frame coupling mechanism for removably coupling the body over an all-terrain vehicle such that the wheels of the all-terrain vehicle extend from the body and a driver is allowed to mount the all-terrain vehicle contained therein through the door aperture.

Abstract: A distributor funnel for receiving friction material and for dispensing the friction material to a mold for a friction product is disclosed. The container comprises first and second half bodies. Pivot joints connect the first and second half bodies pivotally such that they are pivotable relative to one another about a pivot axis. The two half bodies resemble a duck bill which, in a closed position, form a closed funnel receiving the friction material. The two half bodies are spring-biased into the closed position. When the two half bodies are squeezed together at the top, the friction material is dispensed at the bottom of the funnel.