Patents by Inventor Robert L. Rosati

Robert L. Rosati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Estrogen Agonists/Antagonists For Preventing Breast Cancer
    Publication number: 20100317712
    Abstract: Compounds of this formula are useful for preventing breast cancer.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 16, 2010
    Inventors: Kimberly O. Cameron, Paul A. Dasilva-Jardine, Hua Zhu Ke, Robert L. Rosati
  • Pyrazole compounds for treatment of neurodegenerative disorders
    Patent number: 7521464
    Abstract: The invention provides compounds of Formula I: wherein R1, R2, R3, R4, R6, R7, R8 and A are as defined. Compounds of formula I have activity inhibiting production of A?-peptide. The invention also provides pharmaceutical compositions and methods for treating diseases, for example Alzheimer's disease, in mammals comprising compounds of Formula I.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: April 21, 2009
    Assignee: Pfizer Inc.
    Inventors: Yuhpyng L. Chen, Spiros Liras, Robert L. Rosati, Martin P. Allen
  • Prostaglandin agonists
    Patent number: 7442702
    Abstract: This invention relates to prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: October 28, 2008
    Assignee: Pfizer Inc.
    Inventors: Kimberly O. Cameron, Bruce A. Lefker, Robert L. Rosati
  • Pyrazole compounds for treatment of neurodegenerative disorders
    Patent number: 7238721
    Abstract: The invention provides compounds of Formula I: wherein R1, R2, R3, R4, R6, R7, R8, and A are as defined. Compounds of formula I have activity inhibiting production of A?-peptide. The invention also provides pharmaceutical compositions and methods for treating diseases, for example Alzheimer's disease, in mammals comprising compounds of Formula I.
    Type: Grant
    Filed: October 7, 2003
    Date of Patent: July 3, 2007
    Assignee: Pfizer Inc
    Inventors: Yuhpyng L. Chen, Spiros Liras, Robert L. Rosati, Martin P. Allen
  • Prevention of loss and restoration of bone mass by certain prostaglandin agonists
    Patent number: 6998423
    Abstract: Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: February 14, 2006
    Assignee: Pfizer Inc.
    Inventors: Kimberly O. Cameron, Hua Z. Ke, Bruce A. Lefker, Robert L. Rosati, David D. Thompson
  • Method of treating certain cancers using an estrogen agonist/antagonist
    Patent number: 6821989
    Abstract: The present invention provides methods of treating cancer of the liver, ovarian cancer, a desmoid tumor, glioma, pancreatic cancer, or renal cell carcinoma using an estrogen agonist/antagonist. The present invention also provides kits that contain an estrogen agonist/antagonist for treating cancer of the liver, ovarian cancer, a desmoid tumor, glioma, pancreatic cancer, or renal cell carcinoma.
    Type: Grant
    Filed: January 23, 2002
    Date of Patent: November 23, 2004
    Assignee: Pfizer Inc.
    Inventor: Robert L. Rosati
  • Prevention of loss and restoration of bone mass by certain prostaglandin agonists
    Publication number: 20040176461
    Abstract: Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Application
    Filed: August 29, 2003
    Publication date: September 9, 2004
    Applicant: Pfizer Inc
    Inventors: Kimberly O. Cameron, Hua Z. Ke, Bruce A. Lefker, Robert L. Rosati, David D. Thompson
  • Pyrazole compounds for treatment of neurodegenerative disorders
    Publication number: 20040142997
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: October 7, 2003
    Publication date: July 22, 2004
    Inventors: Yuhpyng L. Chen, Spiros Liras, Robert L. Rosati, Martin P. Allen
  • Benzothiophenes and related compounds as estrogen agonists
    Patent number: 6756388
    Abstract: The invention is a compound of Formula (I): wherein R is —OH, R1 is —OH, R2 is —H, n is 2 or 3 and X is sulfur, or a pharmaceutically acceptable salt of a compound having Formula (1), or a pharmaceutical composition comprising a compound having Formula (1) or a pharmaceutically acceptable salt thereof, or methods of treating bone loss, breast cancer or prostate cancer comprising administering an effective amount of the compound having Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: June 29, 2004
    Assignee: Pfizer Inc.
    Inventors: Kimberly O. Cameron, Paul Da Silva-Jardine, Eric R. Larson, James R. Hauske, Robert L. Rosati
  • Compositions and methods for treating conditions responsive to estrogen
    Publication number: 20040092506
    Abstract: This invention relates to methods, pharmaceutical compositions and kits useful in treating conditions responsive to estrogen by the administration of estrogen agonists/antagonists. Conditions responsive to the compositions and methods include rheumatoid arthritis, colon cancer, tissue wounds, skin wrinkles and cataracts. The compositions are comprised of an estrogen agonist/antagonist and a pharmaceutically acceptable vehicle, carrier or diluent. The compositions and methods of treatment are effective while substantially reducing the concomitant liability of adverse effects associated with estrogen administration.
    Type: Application
    Filed: August 29, 2003
    Publication date: May 13, 2004
    Applicant: Pfizer Inc
    Inventors: David D. Thompson, Andrew G. Lee, Wesley W. Day, Robert L. Rosati
  • Prevention of loss and restoration of bone mass by certain prostaglandin agonists
    Patent number: 6649657
    Abstract: Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: November 18, 2003
    Assignee: Pfizer Inc.
    Inventors: Kimberly O. Cameron, Hua Z. Ke, Bruce A. Lefker, Robert L. Rosati, David D. Thompson
  • Compositions and methods for treating conditions responsive to estrogen
    Patent number: 6632834
    Abstract: This invention relates to methods, pharmaceutical compositions and kits useful in treating conditions responsive to estrogen by the administration of estrogen agonists/antagonists. Conditions responsive to the compositions and methods include rheumatoid arthritis, colon cancer, tissue wounds, skin wrinkles and cataracts. The compositions are comprised of an estrogen agonist/antagonist and a pharmaceutically acceptable vehicle, carrier or diluent. The compositions and methods of treatment are effective while substantially reducing the concomitant liability of adverse effects associated with estrogen administration.
    Type: Grant
    Filed: January 11, 2001
    Date of Patent: October 14, 2003
    Assignee: Pfizer Inc.
    Inventors: David D. Thompson, Andrew G. Lee, Wesley W. Day, Robert L. Rosati
  • Method of treating certain cancers using an estrogen agonist/antagonist
    Publication number: 20030130276
    Abstract: The present invention provides methods of treating cancer of the liver, ovarian cancer, a desmoid tumor, glioma, pancreatic cancer, or renal cell carcinoma using an estrogen agonist/antagonist. The present invention also provides kits that contain an estrogen agonist/antagonist for treating cancer of the liver, ovarian cancer, a desmoid tumor, glioma, pancreatic cancer, or renal cell carcinoma.
    Type: Application
    Filed: January 23, 2002
    Publication date: July 10, 2003
    Inventor: Robert L. Rosati
  • Prevention of loss and restoration of bone mass by certain prostaglandin agonists
    Publication number: 20030105092
    Abstract: Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Application
    Filed: September 26, 2002
    Publication date: June 5, 2003
    Inventors: Kimberley Q. Cameron, Hua Z. Ke, Bruce A. Lefker, Robert L. Rosati, David D. Thompson
  • Prostaglandin agonists
    Publication number: 20030078261
    Abstract: This invention relates to prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Application
    Filed: September 25, 2002
    Publication date: April 24, 2003
    Inventors: Kimberly O. Cameron, Bruce A. Lefker, Robert L. Rosati
  • Prostaglandin agonists and their use to treat bone disorders
    Patent number: 6498172
    Abstract: This invention relates to prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: December 24, 2002
    Assignee: Pfizer Inc.
    Inventors: Kimberly O. Cameron, Bruce A. Lefker, Robert L. Rosati
  • Prevention of loss and restoration of bone mass by certain prostaglandin agonists
    Patent number: 6492412
    Abstract: Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: December 10, 2002
    Assignee: Pfizer, Inc.
    Inventors: Kimberly O. Cameron, Hua Z. Ke, Bruce A. Lefker, Robert L. Rosati, David D. Thompson
  • Osteoporosis compounds
    Publication number: 20020165255
    Abstract: This invention relates to prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
    Type: Application
    Filed: October 19, 2001
    Publication date: November 7, 2002
    Inventors: Kimberly O. Cameron, Bruce A. Lefker, Robert L. Rosati
  • Estrogen agonists/antagonists for preventing breast cancer
    Publication number: 20020132816
    Abstract: Compounds of this formula 1
    Type: Application
    Filed: May 16, 2002
    Publication date: September 19, 2002
    Inventors: Kimberly O. Cameron, Paul A. Dasilva-Jardine, Hua Zhu Ke, Robert L. Rosati
  • 5-Substituted-6-cyclic-5,6,7,8-tetrahydronaphthalen 2-ol compounds which are useful for treating osteoporosis
    Patent number: RE39558
    Abstract: Compounds of this formula are useful for treating or preventing, obesity, breast cancer, osteoporosis, endometriosis, cardiovascular disease and prostatic disease.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: April 10, 2007
    Assignee: Pfizer Inc.
    Inventors: Kimberly O. Cameron, Paul A. DaSilva Jardine, Robert L. Rosati