Abstract: A vehicle includes a component coated with a pollutant reduction catalyst configured to remove pollutants from a flow of air over the component, a catalyst temperature sensor coupled to the component, a general temperature sensor, a vehicle speed sensor, and an active grille shutter (AGS) system having a plurality of movable grille shutters. A controller is configured to determine an efficiency of the pollutant reduction catalyst based on signals from the catalyst temperature sensor, the general temperature sensor, the vehicle speed sensor, and the AGS system.

Abstract: A sampling tool for use with an infrared spectrophotometer, and method of use. The sampling tool comprises a bottom plate; and a mesh attached to the bottom plate, the mesh having a plurality of interstitial spaces, and the mesh having a mesh width and a mesh thickness, wherein the mesh is configured to receive a sample material and retain a portion of the sample material within the interstitial spaces of the mesh to form a sample having a sample thickness which is substantially the same as the mesh thickness. The mesh width may be sized to be in a range of about 1 to 3 times the width of an infrared beam directed toward the sampling tool from the spectrophotometer.

Abstract: Methods for analyte detection with magnetic sensors are provided. Aspects of the methods include producing a magnetic sensor device having a magnetically labeled analyte from a sample, such as a serum sample, bound to a surface of a magnetic sensor thereof; and obtaining a signal, e.g., a real-time signal, from the magnetic sensor to determine whether the analyte is present in the sample. Also provided are devices, systems and kits that find use in practicing the methods of the invention. The methods, devices, systems and kits of the invention find use in a variety of different applications, including detection of biomarkers, such as disease markers.

Abstract: A sampling tool for use with an infrared spectrophotometer, and method of use. The sampling tool comprises a bottom plate; and a mesh attached to the bottom plate, the mesh having a plurality of interstitial spaces, and the mesh having a mesh width and a mesh thickness, wherein the mesh is configured to receive a sample material and retain a portion of the sample material within the interstitial spaces of the mesh to form a sample having a sample thickness which is substantially the same as the mesh thickness. The mesh width may be sized to be in a range of about 1 to 3 times the width of an infrared beam directed toward the sampling tool from the spectrophotometer.

Abstract: Methods for analyte detection with magnetic sensors are provided. Aspects of the methods include producing a magnetic sensor device having a magnetically labeled analyte from a sample, such as a serum sample, bound to a surface of a magnetic sensor thereof; and obtaining a signal, e.g., a real-time signal, from the magnetic sensor to determine whether the analyte is present in the sample. Also provided are devices, systems and kits that find use in practicing the methods of the invention. The methods, devices, systems and kits of the invention find use in a variety of different applications, including detection of biomarkers, such as disease markers.

Abstract: Methods for analyte detection with magnetic sensors are provided. Aspects of the methods include producing a magnetic sensor device having a magnetically labeled analyte from a sample, such as a serum sample, bound to a surface of a magnetic sensor thereof; and obtaining a signal, e.g., a real-time signal, from the magnetic sensor to determine whether the analyte is present in the sample. Also provided are devices, systems and kits that find use in practicing the methods of the invention. The methods, devices, systems and kits of the invention find use in a variety of different applications, including detection of biomarkers, such as disease markers.

Abstract: Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.

Abstract: Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.

Abstract: A gas chromatograph oven including a housing, a capillary tube and a thermal control assembly. The housing defining a capillary tube receiving space and having at least one outlet port to permit the passage of a fluid from the capillary tube receiving space of the housing. The capillary tube is positioned in the capillary tube receiving space of the housing and has a gas inlet end connectable to a gas injector and a gas detector end connectable to a gas detector. The thermal control assembly is in fluid communication with the capillary tube receiving space of the housing and is connectable to a source of a temperature regulating fluid.

Abstract: Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.

Abstract: The invention includes devices and methods for forming random arrays of magnetic particles, arrays formed using these devices and methods, and to methods of using the arrays. The invention provides an assembly (chip) with magnetic domains that produce localized magnetic fields capable of immobilizing magnetic particles such as commercially available magnetic beads. Probe or sensor molecules can be coupled to the beads, which are then dispersed on the assembly, forming a random order array. The arrays can be used for analyzing samples, targets, and/or the interaction between samples and targets. The invention finds particular use in processes such as high-throughput genotyping and other nucleic acid hybridization-based assays.

Abstract: Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.

Abstract: A gas chromatograph oven including a housing, a capillary tube and a thermal control assembly. The housing defining a capillary tube receiving space and having at least one outlet port to permit the passage of a fluid from the capillary tube receiving space of the housing. The capillary tube is positioned in the capillary tube receiving space of the housing and has a gas inlet end connectable to a gas injector and a gas detector end connectable to a gas detector. The thermal control assembly is in fluid communication with the capillary tube receiving space of the housing and is connectable to a source of a temperature regulating fluid.

Abstract: A delay locked loop includes a storage element coupled to a data bus and produces a data synchronization signal. A phase detector receives a data clock signal and the data synchronization signal and produces a delay control signal. A first delay circuit produces a signal which is delayed relative to the data clock signal according to the delay control signal. A second delay circuit receiving the delayed signal produces a control signal coupled to a control input of the storage element by delaying the delayed signal an amount which causes the control signal to have a predetermined duty cycle.

Abstract: The present invention provides a magnetic sifter that is small in scale, enables three-dimensional flow in a direction normal to the substrate, allows relatively higher capture rates and higher flow rates, and provides a relatively easy method of releasing captured biomolecules. The magnetic sifter includes at least one substrate. Each substrate contains a plurality of slits, each of which extends through the substrate. The sifter also includes a plurality of magnets attached to the bottom surface of the substrate. These magnets are located proximal to the openings of the slits. An electromagnetic source controls the magnitude and direction of magnetic field gradient generated by the magnets. Either one device may be used, or multiple devices may be used in series. In addition, the magnetic sifter may be used in connection with a detection chamber.

Abstract: Methods for analyte detection with magnetic sensors are provided. Aspects of the methods include producing a magnetic sensor device having a magnetically labeled analyte from a sample, such as a serum sample, bound to a surface of a magnetic sensor thereof; and obtaining a signal, e.g., a real-time signal, from the magnetic sensor to determine whether the analyte is present in the sample. Also provided are devices, systems and kits that find use in practicing the methods of the invention. The methods, devices, systems and kits of the invention find use in a variety of different applications, including detection of biomarkers, such as disease markers.

Abstract: A delay locked loop includes a storage element coupled to a data bus and produces a data synchronization signal. A phase detector receives a data clock signal and the data synchronization signal and produces a delay control signal. A first delay circuit produces a signal which is delayed relative to the data clock signal according to the delay control signal. A second delay circuit receiving the delayed signal produces a control signal coupled to a control input of the storage element by delaying the delayed signal an amount which causes the control signal to have a predetermined duty cycle.

Abstract: A delay locked loop includes a storage element coupled to a data bus and produces a data synchronization signal. A phase detector receives a data clock signal and the data synchronization signal and produces a delay control signal. A first delay circuit produces a signal which is delayed relative to the data clock signal according to the delay control signal. A second delay circuit receiving the delayed signal produces a control signal coupled to a control input of the storage element by delaying the delayed signal an amount which causes the control signal to have a predetermined duty cycle.

Abstract: Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.

Abstract: A delay locked loop includes a storage element coupled to a data bus and produces a data synchronization signal. A phase detector receives a data clock signal and the data synchronization signal and produces a delay control signal. A first delay circuit produces a signal which is delayed relative to the data clock signal according to the delay control signal. A second delay circuit receiving the delayed signal produces a control signal coupled to a control input of the storage element by delaying the delayed signal an amount which causes the control signal to have a predetermined duty cycle.