Abstract: A toothbrush which dispenses dentifrice and dental floss. More specifically, the toothbrush is an assembly including a tubular handle integrally connected to a toothbrush neck and toothbrush head, over which a protective sheath having a floss dispenser is removably attached. A dentifrice dispensing mechanism is provided to drive a supply of dentifrice contained in the tubular handle through a duct and conduit in the toothbrush neck and head. The dispensing mechanism is comprised of a twistable knob, a threaded screw, and a screw driven follower. When the knob is turned the piston moves up to handle to force dentifrice through the brush head and into a outlet passage exiting the toothbrush head between the bristles. A plug of foam-like material is disposed within the conduit of the toothbrush head thereby occluding the outlet passage when the plug is in a decompressed state.