Abstract: A domestic kitchen appliance is provided. The domestic kitchen appliance includes a peltier device having a hot side and a cold side; a hot-side heat-sink attached to the hot side of the peltier device, the hot-side heat-sink configured to remove heat from the hot side of the peltier device and transfer the heat removed from the hot side of the peltier device to a cooking chamber; a cold-side heat-sink attached to the cold side of the peltier device, the cold-side heat-sink fluidly connected to an area to be cooled; and a voltage supply that supplies voltage to the peltier device to cause the peltier device to absorb heat from the cold-side heat-sink into the cold side of the peltier device and to expel heat from the hot side of the peltier device into the hot-side heat-sink. The area to be cooled is outside of the cooking chamber.

Abstract: A domestic cooking appliance for heating a food item includes a main housing; a cooking compartment in the main housing, the cooking compartment being configured to receive the food item to be heated; a shelf located in the cooking compartment and configured to support the food item to be heated; a gas burner configured to provide heat to the cooking compartment; and a perforated panel located between the gas burner and the shelf, the perforated panel having a plurality of openings.

Abstract: Techniques are provided for constructing an appliance door having a metal-to-metal-to-glass bond. In one or more implementations a glass panel is mounted to a door skin of a door panel, the door skin having multiple slots. Adhesive is applied to the side of the door skin opposite the glass panel along a path created by the multiple slots. Afterwards, a metal frame is placed on the adhesive creating a metal-to-metal-to-glass bond with increased structural strength and a reduced gap between the glass and metal of the door panel.

Abstract: A domestic kitchen appliance is provided. The domestic kitchen appliance includes a peltier device having a hot side and a cold side; a hot-side heat-sink attached to the hot side of the peltier device, the hot-side heat-sink configured to remove heat from the hot side of the peltier device and transfer the heat removed from the hot side of the peltier device to a cooking chamber; a cold-side heat-sink attached to the cold side of the peltier device, the cold-side heat-sink fluidly connected to an area to be cooled; and a voltage supply that supplies voltage to the peltier device to cause the peltier device to absorb heat from the cold-side heat-sink into the cold side of the peltier device and to expel heat from the hot side of the peltier device into the hot-side heat-sink. The area to be cooled is outside of the cooking chamber.

Abstract: Techniques are provided for constructing an adjustable kick panel assembly that is removable, adjustable, and attachable without the use of a tool. In one or more implementations, a bracket having a clip is inserted into a slot on a kick panel, and then twisted to secure the bracket to the kick panel. The bracket allows for height adjustment of the kick panel without a tool. The complete kick panel assembly is then attached to the base of an appliance by inserting the clip into a housing on the base.

Abstract: A home cooking appliance includes a housing having a cooktop surface on a top of the housing, a burner on the cooktop surface, a cooking grate disposed above the burner, a cooking compartment in the housing, an oven flue that exhausts air from the cooking compartment, and a flue gas air diverter configured to divert the air exiting from the oven flue under a portion of the cooking grate.

Abstract: Techniques are provided for constructing an adjustable kick panel assembly that is removable, adjustable, and attachable without the use of a tool. In one or more implementations, a bracket having a clip is inserted into a slot on a kick panel, and then twisted to secure the bracket to the kick panel. The bracket allows for height adjustment of the kick panel without a tool. The complete kick panel assembly is then attached to the base of an appliance by inserting the clip into a housing on the base.

Abstract: Techniques are provided for constructing an appliance door having a metal-to-metal-to-glass bond. In one or more implementations a glass panel is mounted to a door skin of a door panel, the door skin having multiple slots. Adhesive is applied to the side of the door skin opposite the glass panel along a path created by the multiple slots. Afterwards, a metal frame is placed on the adhesive creating a metal-to-metal-to-glass bond with increased structural strength and a reduced gap between the glass and metal of the door panel.

Abstract: A home cooking appliance includes a housing having a cooktop surface on a top of the housing, a burner on the cooktop surface, a cooking grate disposed above the burner, a cooking compartment in the housing, an oven flue that exhausts air from the cooking compartment, and a flue gas air diverter configured to divert the air exiting from the oven flue under a portion of the cooking grate.

Abstract: A home cooking appliance includes a housing having a cooktop surface on a top of the housing, a burner on the cooktop surface, a cooking grate disposed above the burner, a cooking compartment in the housing, an oven flue that exhausts air from the cooking compartment, and a flue gas air diverter configured to divert the air exiting from the oven flue under a portion of the cooking grate.

Abstract: Methods useful in constructing libraries that collectively display and/or express members of diverse families of peptides, polypeptides or proteins and the libraries produced using those methods. Methods of screening those libraries and the peptides, polypeptides or proteins identified by such screens.

Abstract: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Abstract: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Abstract: Disclosed are libraries, vectors, phage particles, host cells, and methods for displaying a Kunitz domain. The libraries can include Kunitz domains that vary in at least two interaction loops with respect to one another. Varied Kunitz domains can be displayed on phage at a low valency.

Abstract: In order to obtain a novel binding protein against a chosen target, DNA molecules, each encoding a protein comprising one of a family of similar potential binding domains and a structural signal calling for the display of the protein on the outer surface of a chosen bacterial cell, bacterial spore or phage (genetic package) are introduced into a genetic package. The protein is expressed and the potential binding domain is displayed on the outer surface of the package. The cells or viruses bearing the binding domains which recognize the target molecule are isolated and amplified. The successful binding domains are then characterized. One or more of these successful binding domains is used as a model for the design of a new family of potential binding domains, and the process is repeated until a novel binding domain having a desired affinity for the target molecule is obtained.

Abstract: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Abstract: Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.

Abstract: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.

Abstract: Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.

Abstract: Novel enterokinase cleavage sequences are provided. Also disclosed are methods for the rapid isolation of a protein of interest present in a fusion protein construct including a novel enterokinase cleavage sequence of the present invention and a ligand recognition sequence for capturing the fusion construct on a solid substrate. Preferred embodiments of the present invention show rates of cleavage up to thirty times that of the known enterokinase cleavage substrate (Asp)4-Lys-Ile.