Patents by Inventor Robert Lagace

Robert Lagace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11913066
    Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
    Type: Grant
    Filed: January 26, 2022
    Date of Patent: February 27, 2024
    Assignee: Life Technologies Corporation
    Inventors: Robert Green, Dennis Wang, Julio Mulero, Robert Lagace
  • Patent number: 11471896
    Abstract: A feed box for a decanter centrifuge has a housing with a hollow interior, the housing having a top with an inlet therethrough, a bottom, sides, and opposing open ends, wherein the inlet and the open ends are in fluid communication with the hollow interior. A liner shaped complementary to the hollow interior of the housing, has a top, a bottom, sides, opposing ends, an opening through the top of the liner below the inlet, and a channel through the liner between the opposing ends in fluid communication with the inlet.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: October 18, 2022
    Assignee: 2460257 ONTARIO INC.
    Inventor: Denis Robert Lagace
  • Publication number: 20220205023
    Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
    Type: Application
    Filed: January 26, 2022
    Publication date: June 30, 2022
    Inventors: Robert GREEN, Dennis WANG, Julio MULERO, Robert LAGACE
  • Patent number: 11248256
    Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: February 15, 2022
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Robert Green, Dennis Wang, Julio Mulero, Robert Lagace
  • Publication number: 20210246498
    Abstract: The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids which belong to a panel of single nucleotide polymorphisms (SNPs) useful to identify a human. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences in the panel. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to identify a human.
    Type: Application
    Filed: March 22, 2017
    Publication date: August 12, 2021
    Inventor: Robert LAGACE
  • Publication number: 20200215552
    Abstract: A feed box for a decanter centrifuge has a housing with a hollow interior, the housing having a top with an inlet therethrough, a bottom, sides, and opposing open ends, wherein the inlet and the open ends are in fluid communication with the hollow interior. A liner shaped complementary to the hollow interior of the housing, has a top, a bottom, sides, opposing ends, an opening through the top of the liner below the inlet, and a channel through the liner between the opposing ends in fluid communication with the inlet.
    Type: Application
    Filed: January 6, 2020
    Publication date: July 9, 2020
    Inventor: Denis Robert Lagace
  • Publication number: 20180018422
    Abstract: Systems and methods for calculating a predictive index of identity of a nucleic acid sample using polymorphic genetic marker data are provided. In one embodiment, a predictive index of identity of the nucleic acid sample is calculated using a value from a second set of data from a polymorphic genetic marker that is not linked to a polymorphic genetic marker used to produce a first set of data. In another embodiment, the predictive index of identity is calculated using a value from a second set of data from a polymorphic genetic marker that is linked to a polymorphic genetic marker used to produce the first set of data. Systems and methods for generating an identifier for a biological sample and for verifying a relationship between a biological sample and an identifier are also provided. The identifier is an encoding of a set of values for polymorphic genetic markers.
    Type: Application
    Filed: August 2, 2017
    Publication date: January 18, 2018
    Inventors: Robert LAGACE, Chien-Wei Chang, Lori Hennessy
  • Publication number: 20170335377
    Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
    Type: Application
    Filed: June 5, 2017
    Publication date: November 23, 2017
    Inventors: ROBERT GREEN, DENNIS WANG, JULIO MULERO, ROBERT LAGACE
  • Publication number: 20170253922
    Abstract: The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids which belong to a panel of single nucleotide polymorphisms (SNPs) useful to identify a human. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences in the panel. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to identify a human.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 7, 2017
    Inventor: Robert LAGACE
  • Publication number: 20160154990
    Abstract: Disclosed are devices and methods for collection and analyzing biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature of a test subject, while keeping the sample and signature associated with each other. Such devices and methods are used in forensic, human identification, screening, and access control technologies to rapidly process an individual's identity or determine the identity of an individual.
    Type: Application
    Filed: September 25, 2015
    Publication date: June 2, 2016
    Inventors: Michael Harrold, Lori Hennessy, Robert Lagace
  • Patent number: 9260757
    Abstract: Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci which can cause allelic dropout. Also disclosed are kits useful in human identification.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: February 16, 2016
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Julio Mulero, Michael Malicdem, Robert Lagace
  • Publication number: 20160010146
    Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
    Type: Application
    Filed: July 27, 2015
    Publication date: January 14, 2016
    Inventors: Robert GREEN, Dennis Wang, Julio Mulero, Robert Lagace
  • Publication number: 20150322522
    Abstract: Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci which can cause allelic dropout. Also disclosed are kits useful in human identification.
    Type: Application
    Filed: May 11, 2015
    Publication date: November 12, 2015
    Inventors: Julio MULERO, Michael Malicdem, Robert Lagace
  • Patent number: 9090946
    Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
    Type: Grant
    Filed: September 21, 2011
    Date of Patent: July 28, 2015
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Robert Green, Dennis Wang, Julio Mulero, Robert Lagace
  • Publication number: 20150167068
    Abstract: The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids which belong to a panel of single nucleotide polymorphisms (SNPs) useful to identify a human. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences in the panel. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to identify a human.
    Type: Application
    Filed: July 15, 2013
    Publication date: June 18, 2015
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventor: Robert Lagace
  • Patent number: 9029088
    Abstract: Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci D13S317, TH01, vWA, D12S391 and D6S1043, which can cause allelic dropout. Also disclosed are kits useful in human identification.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: May 12, 2015
    Assignee: Life Technologies Corporation
    Inventors: Julio Mulero, Michael Malicdem, Robert Lagace
  • Publication number: 20140248692
    Abstract: Systems and methods for calculating a predictive index of identity of a nucleic acid sample using polymorphic genetic marker data are provided. In one embodiment, a predictive index of identity of the nucleic acid sample is calculated using a value from a second set of data from a polymorphic genetic marker that is not linked to a polymorphic genetic marker used to produce a first set of data. In another embodiment, the predictive index of identity is calculated using a value from a second set of data from a polymorphic genetic marker that is linked to a polymorphic genetic marker used to produce the first set of data. Systems and methods for generating an identifier for a biological sample and for verifying a relationship between a biological sample and an identifier are also provided. The identifier is an encoding of a set of values for polymorphic genetic markers.
    Type: Application
    Filed: August 13, 2012
    Publication date: September 4, 2014
    Applicant: Life Technologies Corporation
    Inventors: Robert Lagace, Chien-Wei Chang, Lori Hennessy
  • Patent number: 8637655
    Abstract: Disclosed are methods for gender determination in the intron 1 region of the amelogenin locus and a newly discovered single nucleotide polymorphism (SNP) within the X chromosome of the amelogenin locus which can cause allelic dropout. Also disclosed are kits useful in gender determination.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: January 28, 2014
    Assignee: Life Technologies Corporation
    Inventors: Julio Mulero, Robert Green, Robert Lagace, Lori Hennessy
  • Publication number: 20130106568
    Abstract: Disclosed are devices and methods for collection and analyzing biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature of a test subject, while keeping the sample and signature associated with each other. Such devices and methods are used in forensic, human identification, screening, and access control technologies to rapidly process an individual's identity or determine the identity of an individual.
    Type: Application
    Filed: September 14, 2012
    Publication date: May 2, 2013
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Michael HARROLD, Lori HENNESSY, Robert LAGACE
  • Patent number: 8409806
    Abstract: Disclosed are rare short tandem repeat (STR) alleles within the D10S1248 and D12S391 loci in humans. Provided are representative allelic ladders for each locus, methods and assays using these alleles and kits containing allelic ladders comprising these alleles for accurate genotyping and identification of a wide range of individuals.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: April 2, 2013
    Assignee: Life Technologies Corporation
    Inventors: Robert Green, Julio Mulero, Lori Hennessy, Robert Lagace, Chien-Wei Chang