Abstract: A spinal implant includes a first member having a wall that defines an axial cavity. A second member extends between a first end and a second end and defines a longitudinal axis. The second member is configured for disposal with the axial cavity and translation relative to the first member. A third member has an outer surface engageable with tissue and an inner surface disposed to dynamically engage the first end in response to the engagement of the outer surface with the tissue. Systems and methods are disclosed.

Abstract: The invention is directed to methods of modulating Notch signal transduction and to complexes of the protein Mastermind with proteins identified as interacting with Mastermind by a two-hybrid screen as well as a complex of Mastermind (Mam) with Mip1, or a complex of Mam with Mip30, or a complex of Mam with Mip6. Methods of screening the complexes for efficacy in treating and/or preventing certain diseases and disorders, particularly hyperproliferative and cancerous conditions are also provided. The invention includes nucleic acid and amino acid sequences of Mip30 or Mip6, as well as fragments and derivatives thereof.

Abstract: According to the present invention, a lighting control circuit is provided in which various logic gates, transistors and other smaller-scale circuit elements are combined. The circuit receives as inputs the control signals from the vehicle, including the left and right indicator signals, the brake signal and the tail light signal. Each of these signals is fed into a first bank of logic gates whose outputs are supplied to a second bank of logic gates, whose output is in turn supplied to two transistors, each connected to a separate single filament bulb, one for the left side of the vehicle and the other for the right side.

Abstract: An inductive device can heat a body having a slender bore, with an inductor assembly that includes a coolant system. The assembly has a parallel pair of elongate inductors sized to fit deep inside the bore. Each of these inductors has a distal end and a proximal end. The distal ends of the inductors can be electrically interconnected. These inductors are adapted at their proximal ends to connect to a source of current for circulating current along the inductors. The coolant system is adapted to communicate with a source of coolant to circulate coolant along the inductors. The inductors are inserted through the bore of the body to lie lengthwise, without coiling, along the length of the bore. Coolant can then be pumped along the elongate inductors. Then by driving alternating current to flow through the inductors, magnetic coupling to the body occurs to produce heating effects.