Abstract: The present invention provides an efficient synthesis for the preparation of ((1R,3S)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl)[(3S,4S)-3-m ethoxytetrahydro-2H-pyran-4-yl]amine and its succinate salt. The present invention additionally provides an efficient syntheses for the preparation of intermediates (3R)-3-methoxytetrahydro-4H-pyran-4-one; (1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylic acid; and 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine; and for the preparation of the precursor (3S,4S)-N-((1S,4S)-4-isopropyl-4-{[3-(tri-fluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopent-2-en-1-yl)-3-methoxytetrahydro-2H-pyran-4-amine. The invention additionally resides in the superior properties of the succinate salt of ((1R,3S)-3-isopropyl-3-1{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl)[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amine.

Abstract: In one aspect, the invention provides a method for making an electrical connector. The method may include: obtaining a part having a first end portion, a second end portion, and an interim 1 portion between the first and second end portions; flattening the second end portion; trimming the flattened second end portion; and forming a hole in the flattened second end portion.

Abstract: An exemplary fuel cell of the invention includes a formic acid fuel solution in communication with an anode (12, 134), an oxidizer in communication with a cathode (16, 135) electrically linked to the anode, and an anode catalyst that includes Pd. An exemplary formic acid fuel cell membrane electrode assembly (130) includes a proton-conducting membrane (131) having opposing first (132) and second surfaces (133), a cathode catalyst on the second membrane surface, and an anode catalyst including Pd on the first surface.

Abstract: The present invention relates to electrical connectors, and, in particular, to power connectors and to improved contact structures and methods related thereto.

Abstract: Structures and methods for delivering topical compositions are disclosed that fully integrate the topical composition with a carrier. One example adds a liquid topical composition, such as a dental bleach, to a liquid polymer carrier, mixes the two, and then solidifies the mixture. The solidified mixture is a delivery device which is then contacted with the human body in order for the topical composition have its desired effect on the body. Another example embeds the topical composition in an absorbent material. When the absorbent material is contacted with a portion of the human body, the topical composition can have its desired effect.

Abstract: A method and apparatus is provided to simplify sandblasting processes while increasing applied coverage areas in sandblasting operations. The method and apparatus provide a manifold assembly having a plurality of nozzles and that is rigidly attached to an air supply. The manifold is supplied with abrasive material via a plurality of angularly attached sand supply hoses which are coupled to an abrasive material supply. The manifold assembly is pressurized with the supply of air. An article is sandblasted by drawing sand through the hoses and out of the plurality of nozzles using the pressurized air through the manifold assembly.

Abstract: A seal assembly includes an annular hanger having a supporting ledge. An arcuate seal segment includes an outer rail mounted on the ledge and supporting an inner seal. An arcuate carrier is mounted between the hanger and the rail, and includes a piston mounted in a bore. The bore is selectively pressurized to deploy the piston between the hanger and rail for temporarily retracting the seal segment from an adjacent rotor component.

Abstract: The present invention relates to electrical connectors, and, in particular, to power connectors and to improved contact structures and methods related thereto.

Abstract: Various embodiments of the invention may provide one or more non-volatile storage entities, such as a register or a storage array, to store configuration information for a memory device. The specified configuration may then be enabled at the occurrence of a specified event, such as power-up and/or reset.

Abstract: Methods and compositions for detecting a target nucleic acid in a sample are provided. Also provided are methods and compositions for detecting a plurality of target nucleic acids in a sample. Sets of components for use in a subject method are provided; as well as compositions that include a subject set.

Abstract: In one aspect, the invention provides a method for making an electrical connector. The method may include: obtaining a part having a first end portion, a second end portion, and an interim 1 portion between the first and second end portions; flattening the second end portion; trimming the flattened second end portion; and forming a hole in the flattened second end portion.

Abstract: A method and apparatus is provided to simplify sandblasting processes while increasing applied coverage areas in sandblasting operations. The method and apparatus provide a manifold assembly having a plurality of nozzles and that is rigidly attached to an air supply. The manifold is supplied with abrasive material via a plurality of angularly attached sand supply hoses which are coupled to an abrasive material supply. The manifold assembly is pressurized with the supply of air. An article is sandblasted by drawing sand through the hoses and out of the plurality of nozzles using the pressurized air through the manifold assembly.

Abstract: A mirror shade guide for use in dental whitening. A mirror and dental shade guide are combined for a patient to compare his or her teeth to prior to, during, and/or after a dental whitening regimen.

Abstract: A switch-closable double barrel syringe and methods for bleaching teeth using it.

Abstract: A direct organic fuel cell includes a fluid fuel comprising formic acid, an anode having an electrocatalyst comprising palladium nanoparticles, a fluid oxidant, a cathode electrically connected to the anode, and an electrolyte interposed between the anode and the cathode.

Abstract: The addition of the Iodide ion by way of Potassium Iodide to a peroxide such as Hydrogen Peroxide in a basic medium yields Free Radical Oxygen and water; generating large amounts of heat and depleting the Hydrogen Peroxide in a matter of minutes. The Free Radical Oxygen generated in this reaction can be utilized to oxidize organic molecules that produce offending stains on select items, including teeth. Once the Free Radical Oxygen has oxidized the offending molecule the color is lost and the solubility changes allowing the colorless oxidized fragments of the offending molecule to be washed away in the solvent. The Iodide ion catalyzes the reaction allowing for precise control over the speed at which the stain is removed without the need for other expensive, cumbersome energy adding equipment such as lights, lasers, heat sources, etc.

Abstract: The addition of the Iodide ion by way of Potassium Iodide to a peroxide such as Hydrogen Peroxide in a basic medium yields Free Radical Oxygen and water; generating large amounts of heat and depleting the Hydrogen Peroxide in a matter of minutes. The Free Radical Oxygen generated in this reaction can be utilized to oxidize organic molecules that produce offending stains on select items. Once the Free Radical Oxygen has oxidized the offending molecule the color is lost and the solubility changes allowing the colorless oxidized fragments of the offending molecule to be washed away in the solvent. The Iodide ion catalyzes the reaction allowing for precise control over the speed at which the stain is removed without the need for other expensive, cumbersome energy adding equipment such as lights, lasers, heat sources, etc.

Abstract: The addition of the Iodide ion by way of Potassium Iodide to a peroxide such as Hydrogen Peroxide in a basic medium yields Free Radical Oxygen and water; generating large amounts of heat and depleting the Hydrogen Peroxide in a matter of minutes. The Free Radical Oxygen generated in this reaction can be utilized to oxidize organic molecules that produce offending stains on select items, including dental appliances. Once the Free Radical Oxygen has oxidized the offending molecule the color is lost and the solubility changes allowing the colorless oxidized fragments of the offending molecule to be washed away in the solvent. The Iodide ion catalyzes the reaction allowing for precise control over the speed at which the stain is removed without the need for other expensive, cumbersome energy adding equipment such as lights, lasers, heat sources, etc.

Abstract: The addition of the Iodide ion by way of Potassium Iodide to a peroxide such as Hydrogen Peroxide in a basic medium yields Free Radical Oxygen and water; generating large amounts of heat and depleting the Hydrogen Peroxide in a matter of minutes. The Free Radical Oxygen generated in this reaction can be utilized to oxidize organic molecules that produce offending stains on select items, including teeth. Once the Free Radical Oxygen has oxidized the offending molecule the color is lost and the solubility changes allowing the colorless oxidized fragments of the offending molecule to be washed away in the solvent. The Iodide ion catalyzes the reaction allowing for precise control over the speed at which the stain is removed without the need for other expensive, cumbersome energy adding equipment such as lights, lasers, heat sources, etc.

Abstract: A solderless electrical contact has first and second ends for connection to conductive elements joined by a central section having a C-shaped cross-section with opposing arms tapering to a reduced end thickness for press-fit mounting into a printed circuit board aperture. The C-shaped cross-section has a slot arranged therein, the slot having a longitudinal axis parallel to a longitudinal axis of the electrical contact. The tapering arms of the C-shaped cross-section provide uniformly stressed beams that allow the radii of each arm to better conform to tolerance variations of the aperture without creating undue stresses therein and the slot arranged in the C-shaped cross-section reduces an insertion force of the electrical contact while retaining a sufficient retention force of the electrical contact.