Patents by Inventor Robert Lathrop

Robert Lathrop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200069600
    Abstract: Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.
    Type: Application
    Filed: September 11, 2019
    Publication date: March 5, 2020
    Applicant: DFB Soria, LLC
    Inventors: Keith JOHNSON, Robert LATHROP, Meidong YANG, Holly MAULHARDT, Roland FRANKE
  • Publication number: 20200054552
    Abstract: The invention relates to a medicament containing a compound of general formula (I), where R1=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C11-C21 alkyl, alkylene or alkinyl group, preferably a C11-C15 alkyl, alkylene or alkinyl group, particularly a C11-C13 alkyl, alkylene or alkinyl group, most preferably a C13 alkyl group, R2=independently, a straight or branched C1-C8 alkyl, alkylene or alkinyl group, preferably a C1-C6 alkyl, alkylene or alkinyl group, in particular a C2-C4 alkyl, alkylene or alkinyl group, most preferably a C3 alkyl group, a —[CH2—(CH2)m—O]nH group with n=1 to 10, preferably n=1 to 5, to m=1 to 5, preferably m=1 to 3, a —CH2—[CH—(OH)]p [CH2—R3]-group, where R3=independently H or OH, p=1 to 7, preferably p=1 to 4, a pentose group or a hexose group, as therapeutically active agent, alone or in combination with one or several further pharmaceutical agents as a combination preparation for the treatment of viral skin diseases and/or
    Type: Application
    Filed: August 19, 2019
    Publication date: February 20, 2020
    Inventors: Yunik CHANG, Robert LATHROP, Erwin BOHM, Irene GANDER-MEISTERERNST, Regina GREGER, Johanna HOLLDACK, Ulrich MOEBIUS
  • Patent number: 10548630
    Abstract: The present invention relates to a system and apparatus for implementing a method for identifying tube parameters of a curved tube of an active cannula for operating on a target in a patient. The method includes the step (a) of acquiring a model of the patient anatomy including the target. The method also includes the step (b) of selecting a set of parameters characterizing a curved tube. The method also includes the step (c) of computing a workspace for an active cannula having the selected curved tube parameters. The method also includes the step (d) of comparing the workspace to the anatomical model to determine the degree to which an active cannula having the selected curved tube parameters covers the target. The method also includes the step (e) of repeating steps (b) through (d) through a defined number of curved tube parameter sets. The method also includes the step (f) of identifying the curved tube parameters that provide an active cannula with an optimal degree of target coverage.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: February 4, 2020
    Assignee: VANDERBILT UNIVERSITY
    Inventors: Philip J. Swaney, Ray Lathrop, Jessica Burgner, Kyle Weaver, Hunter B. Gilbert, Robert J. Webster, David B. Comber
  • Patent number: 10449162
    Abstract: Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: October 22, 2019
    Assignee: DFB Soria LLC
    Inventors: Keith Johnson, Robert Lathrop, Meidong Yang, Holly Maulhardt, Roland Franke
  • Publication number: 20190314112
    Abstract: An apparatus for supporting a medical device on a patient includes a mounting structure configured to be fitted onto the patient to encircle at least a portion of a body part of the patient. The mounting structure includes an inner layer and an outer layer that define a confinement. A jamming material is contained within the confmement. The jamming material is configured to flow within the confmement to conform to the shape of the body part of the patient onto which the mounting structure is fitted. The mass of jamming material is configured to harden and become rigid in its conformed shape in response to a vacuum being formed in the confinement.
    Type: Application
    Filed: November 7, 2016
    Publication date: October 17, 2019
    Inventors: Patrick Wellborn, Robert J. Webster, III, Ray Lathrop, Richard J. Hendrick
  • Patent number: 10441371
    Abstract: A robotic surgical apparatus includes at least two tubes having a nested, concentric configuration with an inner tube positioned in an outer tube. The tubes are configured to deliver surgical therapy. A first tube carrier connected to the outer tube and a second tube carrier connected to the inner tube. The first tube carrier and its associated outer tube and the second tube carrier and its associated inner tube form a robotic arm assembly. An actuator for actuating the robotic arm assembly is configured to receive the robotic arm assembly via a tube insertion interface into which the robotic arm assembly can be inserted.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: October 15, 2019
    Assignee: VANDERBILT UNIVERSITY
    Inventors: Richard J. Hendrick, Robert J. Webster, III, S. Duke Herrell, Philip J. Swaney, Ray Lathrop
  • Patent number: 10434059
    Abstract: The invention relates to a medicament containing a compound of general formula (I), where R1=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C11-C21 alkyl, alkylene or alkinyl group, preferably a C11-C15 alkyl, alkylene or alkinyl group, particularly a C11-C13 alkyl, alkylene or alkinyl group, most preferably a C13 alkyl group, R2=independently, a straight or branched C1-C8 alkyl, alkylene or alkinyl group, preferably a C1-C6 alkyl, alkylene or alkinyl group, in particular a C2-C4 alkyl, alkylene or alkinyl group, most preferably a C3 alkyl group, a —[CH2—(CH2)m-O]nH group with n=1 to 10, preferably n=1 to 5, to m=1 to 5, preferably m=1 to 3, a —CH2—[CH—(OH)]p[CH2—R3]— group, where R3=independently H or OH, p=1 to 7, preferably p=1 to 4, a pentose group or a hexose group, as therapeutically active agent, alone or in combination with one or several further pharmaceutical agents as a combination preparation for the treatment of viral skin diseases and/or
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: October 8, 2019
    Assignee: Fougera Pharmaceuticals Inc.
    Inventors: Yunik Chang, Robert Lathrop, Erwin Böhm, Irene Gander-Meisterernst, Regina Greger, Johanna Holldack, Ulrich Moebius
  • Patent number: 10307214
    Abstract: A surgical robot system includes a support structure for positioning relative to a patient. The support structure includes a plurality of mounting structures. One or more robotic tool cassettes that are configured to interchangeably connect with any of the mounting structures. Each tool cassette includes a concentric tube manipulator and a transmission for operating the concentric tube manipulator. The support structure also includes a tube collector including a tube assembly associated with each of the mounting structures. The tube assemblies are configured to receive the concentric tube manipulators and guide the manipulators to extend along predetermined trajectories relative to each other.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: June 4, 2019
    Assignee: VANDERBILT UNIVERSITY
    Inventors: Ray Lathrop, Trevor L. Bruns, Arthur W. Mahoney, Hunter B. Gilbert, Philip J. Swaney, Richard J. Hendrick, Kyle Weaver, Paul T. Russell, Stanley Duke Herrell, Robert J. Webster
  • Patent number: 10111956
    Abstract: The present disclosure generally relates to pharmaceutical corticosteroid compositions, and methods of making the same.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: October 30, 2018
    Assignee: Tolmar, Inc.
    Inventors: Robert Lathrop, David Wade Osborne
  • Publication number: 20180193254
    Abstract: The invention relates to a medicament containing a compound of general formula (I), where R1=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C11-C21 alkyl, alkylene or alkinyl group, preferably a C11-C15 alkyl, alkylene or alkinyl group, particularly a C11-C13 alkyl, alkylene or alkinyl group, most preferably a C13 alkyl group, R2=independently, a straight or branched C1-C8 alkyl, alkylene or alkinyl group, preferably a C1-C6 alkyl, alkylene or alkinyl group, in particular a C2-C4 alkyl, alkylene or alkinyl group, most preferably a C3 alkyl group, a —[CH2—(CH2)m-O]nH group with n=1 to 10, preferably n=1 to 5, to m=1 to 5, preferably m=1 to 3, a —CH2—[CH—(OH)]p [CH2—R3]— group, where R3=independently H or OH, p=1 to 7, preferably p=1 to 4, a pentose group or a hexose group, as therapeutically active agent, alone or in combination with one or several further pharmaceutical agents as a combination preparation for the treatment of viral skin diseases and/o
    Type: Application
    Filed: August 18, 2017
    Publication date: July 12, 2018
    Applicant: Fougera Pharmaceuticals Inc.
    Inventors: Yunik CHANG, Robert LATHROP, Erwin BÖHM, Irene GANDER-MEISTERERNST, Regina GREGER, Johanna HOLLDACK, Ulrich MOEBIUS
  • Publication number: 20180177739
    Abstract: Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.
    Type: Application
    Filed: February 19, 2018
    Publication date: June 28, 2018
    Applicant: DFB Soria, LLC
    Inventors: Keith JOHNSON, Robert LATHROP, Meidong YANG, Holly MAULHARDT, Roland FRANKE
  • Patent number: 9770406
    Abstract: The invention relates to a medicament containing a compound of general formula (I), where R1=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C11-C21 alkyl, alkylene or alkinyl group, preferably a C11-C15 alkyl, alkylene or alkinyl group, particularly a C11-C13 alkyl, alkylene or alkinyl group, most preferably a C13 alkyl group, R2=independently, a straight or branched C1-C8 alkyl, alkylene or alkinyl group, preferably a C1-C6 alkyl, alkylene or alkinyl group, in particular a C2-C4 alkyl, alkylene or alkinyl group, most preferably a C3 alkyl group, a —[CH2—(CH2)m-O]nH group with n=1 to 10, preferably n=1 to 5, to m=1 to 5, preferably m=1 to 3, a —CH2—[CH—(OH)]p[CH2—R3]- group, where R3=independently H or OH, p=1 to 7, preferably p=1 to 4, a pentose group or a hexose group, as therapeutically active agent, alone or in combination with one or several further pharmaceutical agents as a combination preparation for the treatment of viral skin diseases and/or
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: September 26, 2017
    Assignee: Medigene AG
    Inventors: Yunik Chang, Robert Lathrop, Erwin Böhm, Irene Gander-Meisterernst, Regina Greger, Johanna Holldack, Ulrich Moebius
  • Publication number: 20160155086
    Abstract: A system for managing delivery of cargo comprises a communications module located in a vehicle. The communications module includes a communications component, a navigation component and an electronic interface. One or more processors remote to the communications module execute a management application which is communicatively coupled to the communications module. The communications component receives from the management application information of the delivery of the cargo to a destination. The electronic interface receives information of at least one additional destination. The navigation component provides navigation instructions to the destination and the at least one additional destination. The navigation component provides navigation instructions through the electronic interface. The communications component receives information of an arrival of the vehicle at a location, the location including one or more of the destination and the at least one additional destination.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 2, 2016
    Inventors: Max L. Fuller, Ken Crane, Scott Davison, Robert Lathrop
  • Patent number: 9164013
    Abstract: The invention concerns reagent delivery system for an apparatus for processing of biological samples arranged on microscope slides, comprising a reagent section having one or more reagent containers; a slide section in which at least one microscope slide is arranged; a probe for dispensing a portion of reagent onto a predetermined microscope slide, and means for handling the probe. The probe comprises a continuous prove tubing element extending through a rigid probe member and connecting the probe tip to a pneumatic pressure regulation device. The reagent containers are adapted for cooperation with the probe tip. In this manner a high though-put and a very low carry over of fluid residues is achieved since there is no assembled parts making up the inside volume of the probe in which the fluid may be retained.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: October 20, 2015
    Assignee: DAKO DENMARK A/S
    Inventors: John Favuzzi, Jonathan Sweda, Loren Bland, Merrit Martin, Robert Lathrop, John Van Bosch, Kristopher Buchanan
  • Publication number: 20150209429
    Abstract: The present disclosure generally relates to pharmaceutical corticosteroid compositions, and methods of making the same.
    Type: Application
    Filed: June 3, 2014
    Publication date: July 30, 2015
    Inventors: Robert Lathrop, David Wade Osborne
  • Publication number: 20140357607
    Abstract: The present disclosure generally relates to pharmaceutical corticosteroid compositions, and methods of making the same.
    Type: Application
    Filed: June 3, 2014
    Publication date: December 4, 2014
    Inventors: Robert Lathrop, David Wade Osborne
  • Publication number: 20140004552
    Abstract: The invention concerns reagent delivery system for an apparatus for processing of biological samples arranged on microscope slides, comprising a reagent section having one or more reagent containers; a slide section in which at least one microscope slide is arranged; a probe for dispensing a portion of reagent onto a predetermined microscope slide, and means for handling the probe. The probe comprises a continuous prove tubing element extending through a rigid probe member and connecting the probe tip to a pneumatic pressure regulation device. The reagent containers are adapted for cooperation with the probe tip. In this manner a high though-put and a very low carry over of fluid residues is achieved since there is no assembled parts making up the inside volume of the probe in which the fluid may be retained.
    Type: Application
    Filed: June 17, 2013
    Publication date: January 2, 2014
    Inventors: John Favuzzi, Jonathan Sweda, Lauren Bland, Merrit Martin, Robert Lathrop, John Van Bosch, Kristopher Buchanan
  • Publication number: 20130002456
    Abstract: A communications module for conveying information to the driver of a truck is provided. The module is designed to reside in the cab of a truck that is carrying a full truckload of cargo. The communications module includes a user interface such as a screen. The communications module also has a modem. The modem is used for communicating with a host trucking management system through a wireless communications system. The communications module has a vehicle navigation system. The vehicle navigation system communicates with a GPS satellite system to generate maps on the user interface. The navigation system allows the driver to refer to a map on a screen for driving directions en route to a cargo pick-up location or other location. Further, the communications module includes a processing unit that is programmed to receive cargo delivery data sets from the host trucking management system.
    Type: Application
    Filed: August 30, 2012
    Publication date: January 3, 2013
    Inventors: Max L. Fuller, Kenneth W. Crane, Robert Lathrop, Scott Davison
  • Patent number: 8285611
    Abstract: A method for transporting cargo using a truck is provided. Preferably, the method is used in connection with full truckload operations. The method generally includes powering up a communications module residing within a cab of the truck. The communications module comprises a vehicle navigation system, a modem for receiving telecommunications signals, a processing unit for associating instructions for cargo delivery locations with geo-positioning coordinates, and a user interface. The method further includes receiving a cargo delivery data set at the communications module. The data set is sent from a host trucking management system. The data set provides at least a first cargo delivery location for the driver. The method then includes the driver acknowledging receipt of the first cargo delivery location through the user interface. Acknowledgment of receipt of the first cargo delivery location causes a signal to be sent from the communications module to the host trucking management system.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: October 9, 2012
    Inventors: Max L. Fuller, Kenneth W. Crane, Robert Lathrop, Scott Davison
  • Publication number: 20110009481
    Abstract: The invention relates to a medicament containing a compound of general formula (I), where R1=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C11-C21 alkyl, alkylene or alkinyl group, preferably a C11-C15 alkyl, alkylene or alkinyl group, particularly a C11-C13 alkyl, alkylene or alkinyl group, most preferably a C13 alkyl group, R2=independently, a straight or branched C1-C8 alkyl, alkylene or alkinyl group, preferably a C1-C6 alkyl, alkylene or alkinyl group, in particular a C2-C4 alkyl, alkylene or alkinyl group, most preferably a C3 alkyl group, a —[CH2—(CH2)m-O]nH group with n=1 to 10, preferably n=1 to 5, to m=1 to 5, preferably m=1 to 3, a —CH2—[CH—(OH)]p[CH2—R3]- group, where R3=independently H or OH, p=1 to 7, preferably p=1 to 4, a pentose group or a hexose group, as therapeutically active agent, alone or in combination with one or several further pharmaceutical agents as a combination preparation for the treatment of viral skin diseases and/or
    Type: Application
    Filed: September 21, 2010
    Publication date: January 13, 2011
    Applicant: MediGene AG
    Inventors: Yunik Chang, Robert Lathrop, Erwin Böhm, Irene Gander-Meisterernst, Regina Greger, Johanna Holldack, Ulrich Moebius