Abstract: Methods and devices for determining the distance between a location emitting an acoustic, photonic, or electromagnetic waveform and a location detecting the emitted waveform are provided. In certain applications the emitting and/or sensing locations may be selected from within a human, mammalian, or animal body. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy. In certain aspects, a bioelectric signal pathway carries a pulse from cardiac pacing pulse generator to deliver a pacing pulse to a heart while protecting a bioelectric measurement device from interference from the pacing pulse.

Abstract: Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

Abstract: Apparatus and methods enable robust, reliable control for implantable medical devices, including cardiac pacemakers, defibrillators and cardiac resynchronization devices. Integrated circuits in the devices have minimized interfaces, can derive power from the interface signals, and have high voltage and latch-up protection. A device lead has a power generation circuit and a switching circuit using cascaded PMOS transistors for operating with a stable voltage despite fluctuations in the supplied voltage. The lead has control electronics that provide a very low impedance between an electrode and a lead conductor during most of the duration of a pacing pulse, but during a brief initial portion of the pacing pulse, provide a very high impedance to permit charging up a power supply that is local to the control electronics. A method of stabilizing the external impedance and a system for fault detection and fault recovery for an implantable device are also provided.

Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

Abstract: Continuous field tomography systems are provided. Aspects of systems include a data aggregating module configured to receive both continuous field tomography data and non-continuous field physiological data and produce an aggregated data product from these disparate types of data. Also provided are methods of using systems of the invention in a variety of different applications, including diagnostic and therapeutic applications. The systems and methods of the invention find use in a variety of different applications, such as cardiac related applications.

Abstract: Embodiments of the present invention enable robust, reliable control functionality for effectors present on intraluminal, e.g., vascular leads, as well as other types of implantable devices. Embodiments of the invention enable the required functionality for accurate long term control of effectors units, even ones present on multiplex carrier configurations, while provide for low power consumption. Aspects of the invention include implantable integrated circuits that have power extraction; energy storage; communication; and device configuration functional blocks, where these functional blocks are all present in a single integrated circuit on an intraluminal-sized support. Also provided by the invention are effector assemblies that include the integrated circuits, as well as implantable medical devices, e.g., pulse generators that include the same, as well as systems and kits thereof and methods of using the same, e.g., in pacing applications, including cardiac resynchronization therapy (CRT) applications.

Abstract: A patient information system and method are described. The system provides patient interaction via a display.

Abstract: A system for providing users access to information of health parameters on patients. The system includes a modem for receiving digital data from one or more patient sources on the health parameters of the patients and a management computer. The management computer processes the digital data and provides clinical statistics and administrative statistics derived from the digital data. Such clinical statistics and administrative statistics can be accessed via Internet protocol by one or more users such that these users each can access the clinical statistics and the administrative statistics independently.

Abstract: This disclosure provides a handheld writing device and a related data entry system. In particular, a digital electronic clipboard is used to mount pages or forms utilized in forms processing applications, such as inventory tracking. A stylus having a writing tip at one end of the stylus and a bar code scanning mechanism at another end of the stylus is used to enter data on the pages or forms and scan bar codes appearing on the pages or forms themselves, or on a separate item to be associated with the form. The system detects whether bar code data or stylus position data is being generated and causes its CPU to responsively process entered data. In an alternative embodiment, the system also permits generation of only one of stylus position data and bar code data at any given time.