Patents by Inventor Robert Lerch

Robert Lerch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240094120
    Abstract: This invention relates to the preparation of N-(phosphonomethyl)glycine (“glyphosate”) from N-(phosphonomethyl)iminodiacetic acid (“PMIDA”), and more particularly to methods for control of the conversion of PMIDA, for the identification of reaction end points relating to PMIDA conversion and the preparation of glyphosate products having controlled PMIDA content.
    Type: Application
    Filed: September 22, 2023
    Publication date: March 21, 2024
    Inventors: Leonard AYNARDI, David Z. BECHER, Robert E. BYRD, Eduardo Aurelio CASANOVA, James P. COLEMAN, David R. EATON, Walter K. GAVLICK, Eric A. HAUPFEAR, Oliver LERCH, Carl MUMFORD, Alfredo OBA, Stephen D. PROSCH, Peter E. ROGERS, Bart ROOSE, Mark D. SCAIA, Lowell R. SMITH, Donald D. SOLETA, John WAGENKNECHT
  • Publication number: 20090246829
    Abstract: Isolated nucleic acid molecules comprising a gene segment from a rhesus rotavirus (RRV) or from one of three rhesus:human reassortant viruses are disclosed, including isolated nucleic acid molecules having a sequence selected from the group consisting of: SEQ ID NO: 1-14, inclusive, and isolated nucleic acid molecules encoding a protein having a sequence selected from the group consisting of SEQ ID NO: 15-28, inclusive, as well as variants of the isolated nucleic acid molecules.
    Type: Application
    Filed: February 3, 2009
    Publication date: October 1, 2009
    Applicants: Services
    Inventors: Deborah A. Buonagurio, Alice F. Georgiu, Robert A. Lerch, Bruce B. Mason, Shridhara C. Murthy, Ruth S. Rappaport, Mohinder S. Sidhu, Stephen A. Udem, Timothy J. Zamb
  • Patent number: 7485415
    Abstract: Isolated nucleic acid molecules comprising a gene segment from a rhesus rotavirus (RRV) or from one of three rhesus: human reassortant viruses are disclosed, including isolated nucleic acid molecules having a sequence selected from the group consisting of: SEQ ID NO: 1-14, inclusive, and isolated nucleic acid molecules encoding a protein having a sequence selected from the group consisting of SEQ ID NO: 15-28, inclusive, as well as variants of the isolated nucleic acid molecules.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: February 3, 2009
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Deborah A. Buonagurio, Alice F. Georgiu, Robert A. Lerch, Bruce B. Mason, Shridhara C. Murthy, Ruth S. Rappaport, Mohinder S. Sidhu, Stephen A. Udem, Timothy J. Zamb
  • Publication number: 20050119471
    Abstract: Isolated nucleic acid molecules comprising a gene segment from a rhesus rotavirus (RRV) or from one of three rhesus: human reassortant viruses are disclosed, including isolated nucleic acid molecules having a sequence selected from the group consisting of: SEQ ID NO: 1-14, inclusive, and isolated nucleic acid molecules encoding a protein having a sequence selected from the group consisting of SEQ ID NO: 15-28, inclusive, as well as variants of the isolated nucleic acid molecules.
    Type: Application
    Filed: February 19, 2003
    Publication date: June 2, 2005
    Applicant: THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Deborah Buonagurio, Alice Georgiu, Robert Lerch, Bruce Mason, Shridhara Murthy, Ruth Rappaport, Mohinder Sidhu, Stephen Udem, Timothy Zamb
  • Publication number: 20040191886
    Abstract: The present invention relates to recombinant DNA molecules which encode bovine respiratory syncytial (BRS) virus proteins, to BRS viral proteins, and peptides and to recombinant BRS virus vaccines produced therefrom. It is based, in part, on the cloning of substantially full length cDNAs which encode the entire BRS virus G, F, and N proteins. According to particular embodiments of the invention, DNA encoding a BRS virus protein or peptide may be used to diagnose BRS virus infection, or, alternatively, may be inserted into an expression vector, including, but not limited to, vaccinia virus as well as bacterial, yeast, insect, or other vertebrate vectors. These expression vectors may be utilized to produce the BRS virus protein or peptide in quantity; the resulting substantially pure viral peptide or protein may be incorporated into subunit vaccine formulations or may be used to generate monoclonal or polyclonal antibodies which may be utilized in diagnosis of BRS virus infection or passive immunization.
    Type: Application
    Filed: April 30, 2004
    Publication date: September 30, 2004
    Inventors: Gail W. Wertz, Robert Lerch
  • Patent number: 6730305
    Abstract: The present invention relates to recombinant DNA molecules which encode bovine respiratory syncytial (BRS) virus proteins, to BRS virus proteins, and peptides and to recombinant BRS virus vaccines produced therefrom. It is based, in part, on the cloning of substantially full length cDNAs which encode the entire BRS virus G, F, and N proteins. According to particular embodiments of the invention, DNA encoding a BRS virus protein or peptide may be used to diagnose BRS virus infection, or, alternatively, may be inserted into an expression vector, including, but not limited to, vaccinia virus as well as bacterial, yeast, insect, or other vertebrate vectors. These expression vectors may be utilized to produce the BRS virus protein or peptide in quantity; the resulting substantially pure viral peptide or protein may be incorporated into subunit vaccine formulations or may be used to generate monoclonal or polyclonal antibodies which may be utilized in diagnosis of BRS virus infection or passive immunization.
    Type: Grant
    Filed: May 8, 2000
    Date of Patent: May 4, 2004
    Assignee: The UAB Research Foundation
    Inventors: Gail W. Wertz, Robert Lerch
  • Patent number: 6060280
    Abstract: The present invention relates to recombinant DNA molecules which encode bovine respiratory syncytial (BRS) virus proteins, to BRS virus proteins, and peptides and to recombinant BRS virus vaccines produced therefrom. It is based, in part, on the cloning of substantially full length cDNAs which encode the entire BRS virus C, F, and N proteins. According to particular embodiments of the invention, DNA encoding a BRS virus protein or peptide may be used to diagnose BRS virus infection, or, alternatively, may be inserted into an expression vector, including, but not limited to, vaccinia virus as well as bacterial, yeast, insect, or other vertebrate vectors. These expression vectors may be utilized to produce the BRS virus protein or peptide in quantity; the resulting substantially pure viral peptide or protein may be incorporated into subunit vaccine formulations or may be used to generate monoclonal or polyclonal antibodies which may be utilized in diagnosis of BRS virus infection or passive immunization.
    Type: Grant
    Filed: September 8, 1993
    Date of Patent: May 9, 2000
    Assignee: The UAB Research Foundation
    Inventors: Gail W. Wertz, Robert Lerch