Patents by Inventor Robert Leroy Heinrikson

Robert Leroy Heinrikson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alzheimer's disease secretase
    Patent number: 7812123
    Abstract: The present invention provides the enzyme and enzymatic procedures for cleaving the ? secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays.
    Type: Grant
    Filed: September 14, 2004
    Date of Patent: October 12, 2010
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Mark E. Gurney, Michael Jerome Bienkowski, Robert Leroy Heinrikson, Luis A. Parodi, Riqiang Yan
  • Alzheimer's disease secretase
    Patent number: 6835565
    Abstract: The present invention provides the enzyme and enzymatic procedures for cleaving the &bgr; secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: December 28, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventors: Mark E. Gurney, Michael Jerome Bienkowski, Robert Leroy Heinrikson, Luis A. Parodi, Riqiang Yan
  • Heparanase II, a novel human heparanase paralog
    Publication number: 20040171535
    Abstract: The present invention provides a cDNA encoding a heretofore unknown enzyme termed heparanase II; constructs and recombinant host cells incorporating the cDNA; the heparanase II polypeptide encoded by the gene; antibodies to the polypeptide; and methods of making an using all of the foregoing.
    Type: Application
    Filed: October 24, 2002
    Publication date: September 2, 2004
    Inventors: Robert Leroy Heinrikson, Michael Jerome Bienkowski
  • Heparanase II, a novel human heparanase paralog
    Publication number: 20020064853
    Abstract: The present invention provides a cDNA encoding a heretofore unknown enzyme termed heparanase II; constructs and recombinant host cells incorporating the cDNA; the heparanase II polypeptide encoded by the gene; antibodies to the polypeptide; and methods of making and using all of the foregoing.
    Type: Application
    Filed: April 17, 2001
    Publication date: May 30, 2002
    Inventors: Robert Leroy Heinrikson, Michael Jerome Bienkowski
  • Human platelet heparanase polypeptides, polynucleotide molecules that encode them, and methods for the identification of compounds that alter heparanase activity
    Patent number: 6387643
    Abstract: The present invention provides isolated human heparanase polypeptides, and the isolated polynucleotide molecules that encode them, as well as vectors and host cells comprising such polynucleotide molecules. The invention also provides a method for the identification of an agent that alters heparanase activity.
    Type: Grant
    Filed: February 18, 1999
    Date of Patent: May 14, 2002
    Assignee: Pharmacia and Upjohn Company
    Inventors: Robert Leroy Heinrikson, Michael B. Fairbanks, Ana M. Mildner
  • Method for autoactivation of procaspase 8
    Publication number: 20020045205
    Abstract: A novel recombinant procaspase 8 protein lacking the death effector domains and a method for converting said novel procaspase protein to full active human caspase 8 by concentration of the procaspase 8 on a collection device.
    Type: Application
    Filed: May 22, 2001
    Publication date: April 18, 2002
    Inventors: Robert Leroy Heinrikson, Alfredo Giuseppe Tomasselli, Kenneth A. Koeplinger
  • Method for autoactivation of procaspase 8
    Patent number: 6303329
    Abstract: A novel recombinant procaspase 8 protein lacking the death effector domains and a method for converting said novel procaspase protein to full active human caspase 8 by concentration of the procaspase 8 on a collection device.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: October 16, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Robert Leroy Heinrikson, Alfredo Giuseppe Tomasselli, Kenneth A. Koeplinger