Abstract: There are provided herein, inter alia, complexes, compositions and methods for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acid, into a cell. The complexes, compositions and methods may facilitate complexation, protection, delivery and release of oligonucleotides and polyanionic cargos into lung cells and lung tissue, both in vitro and in vivo.

Abstract: There are provided herein, inter alia, complexes, compositions and methods for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acid, into a cell. The complexes, compositions and methods may facilitate complexation, protection, delivery and release of oligonucleotides and polyanionic cargos into target cells, tissues, and organs both in vitro and in vivo.

Abstract: A computer server system and method are disclosed for personalization and customizable filtering of network search results and search result rankings, such as for Internet searching. A representative server system comprises: a network interface to receive a query from a respondent or co-respondent; at least one data storage device storing a plurality of return queries; and one or more processors adapted to access the data storage device and using the query, to select the return queries for transmission; to search the data storage device for corresponding pluralities of responses to the return queries from other co-respondents or respondents; to pair-wise score the responses and generate pair-wise alignment scores for respondent and co-respondent combinations; to sort and rank the combinations according to the alignment scores; and to output a listing of the sorted and ranked respondents or co-respondents to form the personalized network search results and search result rankings.

Abstract: Shot-peening powder that has ceramic particles. The powder having more than 95% by mass of beads. The beads having a median size D50 greater than 50 ?m and less than 1200 ?m, and having a value (D90?D10)/D50, or “S”, such that S??0.126·ln(D50)+0.980.

Abstract: A computer server system and method are disclosed for personalization and customizable filtering of network search results and search result rankings, such as for Internet searching. A representative server system comprises: a network interface to receive a query from a respondent or co-respondent; at least one data storage device storing a plurality of return queries; and one or more processors adapted to access the data storage device and using the query, to select the return queries for transmission; to search the data storage device for corresponding pluralities of responses to the return queries from other co-respondents or respondents; to pair-wise score the responses and generate pair-wise alignment scores for respondent and co-respondent combinations; to sort and rank the combinations according to the alignment scores; and to output a listing of the sorted and ranked respondents or co-respondents to form the personalized network search results and search result rankings.

Abstract: A combined net structure is disclosed that comprises a non-planar coarse net with a grid-like structure comprising a plurality of coarse cables wherein longitudinal coarse cables intersect with latitudinal coarse cables to form a plurality of coarse cells and cutouts of a fine net attached to the coarse net, wherein the fine net comprises a plurality of adjacent fine cables. Each non-edge fine cable is attached to two adjacent fine cables on each of its sides at a plurality of locations along their lengths forming attachment points, wherein the fine net is arranged in a form of an array of fine quadrangular cells with said attachment points constituting the vertices of the fine quadrangular cells. System that comprises the combined net structures are disclosed as well.

Abstract: Compositions and methods for mitigating SVD mechanisms in BHV, including non-calcific SVD mechanisms, are provided.

Abstract: This document provides novel compositions and methods utilizing immunomodulating agents that can stimulate or indirectly augment the immune system, or can have an immunosuppressive effect. TNFR25 agonists disclosed herein have an anti-inflammatory and healing effect. They can be used, e.g., to treat disease caused by asthma and chronic inflammation, such as inflammatory bowel diseases including ulcerative colitis and Crohn's Disease. TNFR25 antagonists disclosed herein can inhibit CD8 T cell-mediated cellular immune responses and can, for example, mitigate organ or tissue rejection following a tissue transplantation. TNFR25 agonists disclosed herein represent biological response modifiers that alter the interaction between the body's cellular immune defenses and cancer cells to boost, direct, or restore the body's ability to fight the cancer when given with tumor vaccines.

Abstract: This document provides novel compositions and methods utilizing immunomodulating agents that can stimulate or indirectly augment the immune system, or can have an immunosuppressive effect. TNFR25 agonists disclosed herein have an anti-inflammatory and healing effect. They can be used, e.g., to treat disease caused by asthma and chronic inflammation, such as inflammatory bowel diseases including ulcerative colitis and Crohn's Disease. TNFR25 antagonists disclosed herein can inhibit CD8 T cell-mediated cellular immune responses and can, for example, mitigate organ or tissue rejection following a tissue transplantation. TNFR25 agonists disclosed herein represent biological response modifiers that alter the interaction between the body's cellular immune defenses and cancer cells to boost, direct, or restore the body's ability to fight the cancer when given with tumor vaccines.

Abstract: A computer server system and method are disclosed for personalization and customizable filtering of network search results and search result rankings, such as for Internet searching. A representative server system comprises: a network interface to receive a query from a respondent or co-respondent; at least one data storage device storing a plurality of return queries; and one or more processors adapted to access the data storage device and using the query, to select the return queries for transmission; to search the data storage device for corresponding pluralities of responses to the return queries from other co-respondents or respondents; to pair-wise score the responses and generate pair-wise alignment scores for respondent and co-respondent combinations; to sort and rank the combinations according to the alignment scores; and to output a listing of the sorted and ranked respondents or co-respondents to form the personalized network search results and search result rankings.

Abstract: A computer server system and method are disclosed for personalization and customizable filtering of network search results and search result rankings, such as for Internet searching. A representative server system comprises: a network interface to receive a query from a respondent or co-respondent; at least one data storage device storing a plurality of return queries; and one or more processors adapted to access the data storage device and using the query, to select the return queries for transmission; to search the data storage device for corresponding pluralities of responses to the return queries from other co-respondents or respondents; to pair-wise score the responses and generate pair-wise alignment scores for respondent and co-respondent combinations; to sort and rank the combinations according to the alignment scores; and to output a listing of the sorted and ranked respondents or co-respondents to form the personalized network search results and search result rankings.

Abstract: Shot-peening method. Projecting a powder onto a surface. The powder includes sintered particles, more than 95 wt % of the particles are beads. The powder has, in wt % based on the oxides: —ZrO2 partially stabilized with CeO2 and Y2O3: balance to 100%, CeO2 and Y2O3 present, in mol % according to the sum of ZrO2, CeO2 and Y2O3, CeO2: 2.5-11 mol % and Y2O3: 0.5-2 mol %, —Al2O3; 3-50%—additive chosen from CaO, manganese oxides, ZnO, praseodymium oxides, SrO, copper oxides, 0.2-6% Nd2O3, BaO, iron oxides, and mixtures thereof: CaO being less than 2%, —elements other than ZrO2, CeO2, Y2O3, Al2O3, CaO, manganese oxides, ZnO, praseodymium oxides, ?5% SrO, copper oxides, Nd2O3, BaO, and iron oxides: manganese oxides, praseodymium oxides, copper oxides and iron oxides being expressed as MnO, Pr6O11, CuO and Fe2O3, respectively, and a relative density greater than 95%.

Abstract: Shot-peening powder that has ceramic particles. The powder having more than 95% by mass of beads. The beads having a median size D50 greater than 50 ?m and less than 1200 ?m, and having a value (D90?D10)/D50, or “S”, such that S??0.126·ln(D50)+0.980.

Abstract: A combined net structure is disclosed that comprises a non-planar coarse net with a grid-like structure comprising a plurality of coarse cables wherein longitudinal coarse cables intersect with latitudinal coarse cables to form a plurality of coarse cells and cutouts of a fine net attached to the coarse net, wherein the fine net comprises a plurality of adjacent fine cables. Each non-edge fine cable is attached to two adjacent fine cables on each of its sides at a plurality of locations along their lengths forming attachment points, wherein the fine net is arranged in a form of an array of fine quadrangular cells with said attachment points constituting the vertices of the fine quadrangular cells. System that comprises the combined net structures are disclosed as well.

Abstract: The present invention relates to methods for modulating regulatory T cells (Tregs) for use, e.g., in treating or preventing graft-versus-host disease (GVHD) in a transplant recipient.

Abstract: This document provides novel compositions and methods utilizing immunomodulating agents that can stimulate or indirectly augment the immune system, or can have an immunosuppressive effect. TNFR25 agonists disclosed herein have an anti-inflammatory and healing effect. They can be used, e.g., to treat disease caused by asthma and chronic inflammation, such as inflammatory bowel diseases including ulcerative colitis and Crohn's Disease. TNFR25 antagonists disclosed herein can inhibit CD8 T cell-mediated cellular immune responses and can, for example, mitigate organ or tissue rejection following a tissue transplantation. TNFR25 agonists disclosed herein represent biological response modifiers that alter the interaction between the body's cellular immune defenses and cancer cells to boost, direct, or restore the body's ability to fight the cancer when given with tumor vaccines.

Abstract: Systems and methods applicable, for instance, to using machine learning models to aid higher education administration. Various machine learning model-based tools can be provided. Further provided can be various infrastructure software modules.

Abstract: This document provides novel compositions and methods utilizing immunomodulating agents that can stimulate or indirectly augment the immune system, or can have an immunosuppressive effect. TNFR25 agonists disclosed herein have an anti-inflammatory and healing effect. They can be used, e.g., to treat disease caused by asthma and chronic inflammation, such as inflammatory bowel diseases including ulcerative colitis and Crohn's Disease. TNFR25 antagonists disclosed herein can inhibit CD8 T cell-mediated cellular immune responses and can, for example, mitigate organ or tissue rejection following a tissue transplantation. TNFR25 agonists disclosed herein represent biological response modifiers that alter the interaction between the body's cellular immune defenses and cancer cells to boost, direct, or restore the body's ability to fight the cancer when given with tumor vaccines.

Abstract: A computer server system and method are disclosed for personalization and customizable filtering of network search results and search result rankings, such as for Internet searching. A representative server system comprises: a network interface to receive a query from a respondent or co-respondent; at least one data storage device storing a plurality of return queries; and one or more processors adapted to access the data storage device and using the query, to select the return queries for transmission; to search the data storage device for corresponding pluralities of responses to the return queries from other co-respondents or respondents; to pair-wise score the responses and generate pair-wise alignment scores for respondent and co-respondent combinations; to sort and rank the combinations according to the alignment scores; and to output a listing of the sorted and ranked respondents or co-respondents to form the personalized network search results and search result rankings.

Abstract: A computer server system and method are disclosed for personalization and customizable filtering of network search results and search result rankings, such as for Internet searching. A representative server system comprises: a network interface to receive a query from a respondent or co-respondent; at least one data storage device storing a plurality of return queries; and one or more processors adapted to access the data storage device and using the query, to select the return queries for transmission; to search the data storage device for corresponding pluralities of responses to the return queries from other co-respondents or respondents; to pair-wise score the responses and generate pair-wise alignment scores for respondent and co-respondent combinations; to sort and rank the combinations according to the alignment scores; and to output a listing of the sorted and ranked respondents or co-respondents to form the personalized network search results and search result rankings.