Abstract: Systems and methods for assessment and management of adverse event risks in mechanical circulatory support patients are described herein. The method for post-operative risk mitigation in patients with an implanted Ventricular Assist Device (VAD) can include receiving a plurality of features relating to an attribute associated with the patient and ingesting at least some of the features into a multistate model. The multistate model can include a plurality of states, each corresponding to a patient condition. The method can include generating with the multistate model a daily prediction of a likelihood of the patient developing at least one of the conditions corresponding to the plurality of states in a predetermined time period, and controlling a user interface to output an indicator of the likelihood of the patient developing the at least one of the conditions in the predetermined time period.

Abstract: The present disclosure provides an orthodontic article including the reaction product of the polymerizable composition. Further, the present disclosure provides polymerizable compositions and methods of making an orthodontic article. The method includes obtaining a polymerizable composition and selectively curing the polymerizable composition to form an orthodontic article. Further, methods are provided, including receiving, by a manufacturing device having one or more processors, a digital object comprising data specifying an orthodontic article; and generating, with the manufacturing device by an additive manufacturing process, the orthodontic article based on the digital object. A system is also provided, including a display that displays a 3D model of an orthodontic article; and one or more processors that, in response to the 3D model selected by a user, cause a 3D printer to create a physical object of an orthodontic article.

Abstract: A method comprises storing first transaction data for a first transaction producing a first version of a first dataset, second transaction data for a second transaction transforming a first version of the first dataset to a second version of the first dataset, and third transaction data for a third transaction transforming the second version of the first dataset to a third version of the first dataset; storing dependency information indicating a first dependency of the third transaction on the second transaction and a second dependency of the second transaction on the first transaction; receiving a first instruction to revoke a first permission of a first user to access the second version of the first dataset; automatically revoking a certain permission of the first user to access the third version of the first dataset based on the dependency information.

Abstract: The present disclosure provides systems and methods for assessing a mental state of a subject in a single session or over multiple different sessions, using for example an automated module to present and/or formulate at least one query based in part on one or more target mental states to be assessed. The query may be configured to elicit at least one response from the subject. The query may be transmitted in an audio, visual, and/or textual format to the subject to elicit the response. Data comprising the response from the subject can be received. The data can be processed using one or more individual, joint, or fused models. One or more assessments of the mental state associated with the subject can be generated for the single session, for each of the multiple different sessions, or upon completion of one or more sessions of the multiple different sessions.

Abstract: The technology disclosed herein accelerates traversal of a privilege graph indicating access permissions to resources of data environments. In a particular example, a method provides identifying a first node type of a start node of a plurality of nodes in a privilege graph and a second node type of an end node of the plurality of nodes. The privilege graph indicates access privileges for a plurality of users to features of a plurality of data environments. The method also provides identifying one or more possible paths between the first node type and the second node type based on a schema of the privilege graph and traversing the plurality of nodes from the start node to the end node while ignoring paths that are not included in the one or more possible paths.

Abstract: Provided are methods of treating cancer comprising administering to a patient in need thereof a poly (ADP-ribose) polymerase (PARP) inhibitor and a salt-induced kinase 2 (SIK2) inhibitor. Also provided are methods for increasing the duration of remission for cancer, and for enhancing the sensitivity of PARP inhibitors for cancer.

Abstract: Systems, methods, and apparatus to select an enhanced write pulse for a write operation in a memory device. In one approach, stronger reset pulses are triggered when there is an increased risk of memory cell threshold voltage degradation. Memory cells read by a relatively higher number of read operations are recorded by a controller of a memory device by updating a lookup table with addresses of the memory cells read. For a new write operation, the controller determines if a reset on set write operation is to be performed. The controller also searches the lookup table to determine if an address for the target bits or codeword of the write operation are in the lookup table. If both conditions are satisfied, then the magnitude of the write pulse is increased for programming the memory cells.

Abstract: A low cost, reduced form factor, high performance electronic device for use in electronic circuits and methods. In one exemplary embodiment, the device includes a unitary header assembly construction that ensures device coplanarity and also includes vertically oriented terminal pins. The device utilizes preconfigured flat coil windings that are disposed directly within a planar core. The flat coil windings further include features that are configured to mate with the header assembly terminal pins which substantially simplify the manufacturing process. Methods for manufacturing the device are also disclosed.

Abstract: A retort furnace for heat and/or thermochemical treatment designed for technological process in protective gas atmosphere, process gas atmosphere or in vacuum, and used inter alia for annealing pipes made of austenitic alloys, having among other things: a cylindrical outer body with a lid equipped with an active thermal barrier, a cylindrical retort, thermal insulation, a heating system located in the thermal insulation, a cooling system of the furnace. The active thermal barrier constitutes the radiation screens, in the form of at least two metal boards, installed on brackets located at the lid inside the retort. Additionally, radiation caulking rings are located in the extreme areas of the brackets and, circumferential sealing rings are permanently fixed in the casing of the retort.

Abstract: A low cost, reduced form factor, high performance electronic device for use in electronic circuits and methods. In one exemplary embodiment, the device includes a unitary header assembly construction that ensures device coplanarity and also includes vertically oriented terminal pins. The device utilizes preconfigured flat coil windings that are disposed directly within a planar core. The flat coil windings further include features that are configured to mate with the header assembly terminal pins which substantially simplify the manufacturing process. Methods for manufacturing the device are also disclosed.

Abstract: Optical assemblies for use in medical or other devices so as to image an object under examination onto an image sensor include a plurality of lens elements that can be retained in lens barrel. The lens elements and the lens barrel can be sealed with a compressible gasket. In one example, at least one lens element is made of an injection-moldable plastic and at least one lens element is made of a relatively dispersive optical glass. A lens barrel diameter or lens diameter can be selected to permit access to the object under examination with surgical or other tools. Aperture plates can be situated so as to reduce flare in the object image.

Abstract: Optical assemblies for use in medical or other devices so as to image an object under examination onto an image sensor include a plurality of lens elements that can be retained in lens barrel. The lens elements and the lens barrel can be sealed with a compressible gasket. In one example, at least one lens element is made of an injection-moldable plastic and at least one lens element is made of a relatively dispersive optical glass. A lens barrel diameter or lens diameter can be selected to permit access to the object under examination with surgical or other tools. Aperture plates can be situated so as to reduce flare in the object image.

Abstract: Optical assemblies for use in medical or other devices so as to image an object under examination onto an image sensor include a plurality of lens elements that can be retained in lens barrel. The lens elements and the lens barrel can be sealed with a compressible gasket. In one example, at least one lens element is made of an injection-moldable plastic and at least one lens element is made of a relatively dispersive optical glass. A lens barrel diameter or lens diameter can be selected to permit access to the object under examination with surgical or other tools. Aperture plates can be situated so as to reduce flare in the object image.

Abstract: The present invention relates to a method for the manufacture of a lavatory dispensing device useful for the delivery of at least one treatment composition, preferably a cleaning composition and/or a sanitizing composition to a sanitary appliance.

Abstract: Optical assemblies for use in medical or other devices so as to image an object under examination onto an image sensor include a plurality of lens elements that can be retained in lens barrel. The lens elements and the lens barrel can be sealed with a compressible gasket. In one example, at least one lens element is made of an injection-moldable plastic and at least one lens element is made of a relatively dispersive optical glass. A lens barrel diameter or lens diameter can be selected to permit access to the object under examination with surgical or other tools. Aperture plates can be situated so as to reduce flare in the object image.

Abstract: A manufacturing method of an embedded inductor comprises the steps of: pre-forming a magnetic core having at least two side walls for defining an accommodating space, disposing a coil in the accommodating space of the magnetic core, and pressing the magnetic core for deconstructing and redistributing tops of the side walls to cover the coil.

Abstract: Foamed two-part hard surface treatment composition which is formed by the admixture of two aqueous compositions, particularly (a) an aqueous alkaline composition comprising a bleach constituent, with (b) an aqueous acidic composition comprising a peroxide constituent, which compositions are kept separate, but which are admixed immediately prior to use or upon use to form a foamed hard surface treatment composition. The foamed two-part hard surface treatment composition are particularly useful in the cleaning of hard surfaces. Preferred foamed two-part hard surface treatment composition provide both a cleaning and sanitizing or disinfecting benefit to hard surfaces, while releasing little or no free chlorine gas to the ambient air.

Abstract: Aqueous compositions comprising a synergistic combination of sodium hydroxide, sodium dodecylbenzene sulfonate, and either benzyl alcohol or propylene glycol phenyl ether are described. The compositions provide good germicidal efficacy against both Gram positive and Gram negative bacteria on hard surfaces and the like. Processes for the sanitization of hard surfaces wherein the presence of Gram positive and/or Gram negative bacteria is suspected are also disclosed.