Abstract: Described herein are recombinant fermenting organisms having a heterologous polynucleotide encoding an alpha-amylase and/or a heterologous polynucleotide encoding a trehalase. Also described are processes for producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant fermenting organisms.

Abstract: Described herein are recombinant fermenting organisms having a heterologous polynucleotide encoding an alpha-amylase and/or a heterologous polynucleotide encoding a trehalase. Also described are processes for producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant fermenting organisms.

Abstract: A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mes

Abstract: A system for object recognition having an imaging device for capturing images of objects; a memory for storing captured images of objects; and a processor for performing object recognition to identify objects in the captured images and managing a database of identified objects in a user inventory. The system is configured to capture and store images, identify objects in the stored captured images, and cross-reference identified objects with a pre-stored library corresponding to a user inventory. The system may further cross-reference the user inventory with a project library to identify projects that a user may complete with the objects identified in their inventory, as well as projects that the user may complete if additional objects are added to their inventory. When identifying projects that may be completed with acquisition of additional objects, the system preferably identifies the additional objects needed for acquisition.

Abstract: The present disclosure relates to an improved implantable drug delivery device, method, and system that is powered by compression and expansion of an inert gas contained within a compressible bellows and surrounded by a biocompatible housing that forms a reservoir which is connected to restricted channel for flow rate control and further connected to a flexible reinforced catheter that delivers medicants from the reservoir to the intrathecal space or other desired bodily tissue.

Abstract: A base plate for supporting a plurality of interlocking building bricks includes a planar sheet having a top surface and a bottom surface, with a plurality of nodes projecting from the top surface. The plurality of nodes includes a node having a vertical cylindrical wall and a horizontal top wall, the vertical cylindrical wall tapering along its vertical height; the node also having a bevel extending around a circumference of the node at an edge where the vertical cylindrical wall transitions to the horizontal top wall. A method of assembling a composite base plate includes securing two component base plates to one another via a common backing material. A method of printing on a base plate includes applying ultraviolet ink to at least the top surface of the base plate from an ultraviolet light printer, the base plate having a plurality of studs or nodes projecting from the top surface.

Abstract: A positive displacement pump can include a pump mechanism having a shaft configured to rotate about its long axis; a screw rod having a continuous thread around the circumference of the screw rod, the thread configured with an upward and downward thread component wherein the screw rod is operatively coupled to the shaft and reticulates along the long axis when the shaft is rotated about the long axis; a stylus positioned to engage the thread of the screw rod; cylindrical body forming a cavity configured to house at least a portion of the screw rod and allow movement of the screw rod along the long axis of the cylindrical body providing a pumping action in the cylindrical body cavity; an inlet and an outlet provided in the cylindrical body walls fluidly coupling the cylindrical body cavity with one or more external fluid paths.

Abstract: A base plate for supporting a plurality of interlocking building bricks includes a planar sheet having a top surface and a bottom surface, with a plurality of nodes projecting from the top surface. The plurality of nodes includes a node having a vertical cylindrical wall and a horizontal top wall, the vertical cylindrical wall tapering along its vertical height; the node also having a bevel extending around a circumference of the node at an edge where the vertical cylindrical wall transitions to the horizontal top wall. A method of assembling a composite base plate includes securing two component base plates to one another via a common backing material. A method of printing on a base plate includes applying ultraviolet ink to at least the top surface of the base plate from an ultraviolet light printer, the base plate having a plurality of studs or nodes projecting from the top surface.

Abstract: Described herein are Saccharomyces cerevisiae strains MBG5038 and MBG5012 deposited under the Budapest Treaty and having accession Nos. NRRL Y67549 and NRRL Y67700, respectively, or a derivatives of strains NRRL Y67549 or Y67700 which exhibit one or more properties or defining characteristics of Saccharomyces cerevisiae strains MBG5038 or MBG5012. Also described are compositions comprising the Saccharomyces yeast and naturally occurring and/or non-naturally occurring components, as well as are processes for producing ethanol from starch-containing material using the strains.

Abstract: A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mes

Abstract: Described herein are recombinant fermenting organisms having a heterologous polynucleotide encoding an alpha-amylase and/or a heterologous polynucleotide encoding a trehalase. Also described are processes for producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant fermenting organisms.

Abstract: A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mes

Abstract: Described herein are Saccharomyces cerevisiae strains MBG5038 and MBG5012 deposited under the Budapest Treaty and having accession Nos. NRRL Y67549 and NRRL Y67700, respectively, or a derivatives of strains NRRL Y67549 or Y67700 which exhibit one or more properties or defining characteristics of Saccharomyces cerevisiae strains MBG5038 or MBG5012. Also described are compositions comprising the Saccharomyces yeast and naturally occurring and/or non-naturally occurring components, as well as are processes for producing ethanol from starch-containing material using the strains.

Abstract: A vacuum assisted suction and irrigation system includes a suction and irrigation wand, an irrigation fluid supply, a vacuum source, and a dual impeller fluid pump. The vacuum source is connected to a suction valve of the suction and irrigation wand to provide suction within the suction and irrigation wand. The irrigation fluid supply is connected to the suction and irrigation wand via the dual impeller fluid pump to supply pressurized irrigation fluid to the suction and irrigation wand. The vacuum source is connected to the fluid pump to pressurize the irrigation fluid being delivered to the suction and irrigation wand.

Abstract: In certain embodiments the present invention provides methods useful in the treatment of glioma, such as glioblastoma, such methods comprising administering to a subject in need thereof a CSF-IR inhibitor together with one or more additional active agents such as IGF-IR inhibitors, PI3K inhibitors, IL4 inhibitors, NFAT inhibitors, and/or Stat6 inhibitors. In certain embodiments the present invention provides pharmaceutical compositions comprising a CSF-IR inhibitor together with one or more of such additional active agents.

Abstract: A dual-diaphragm loudspeaker driver assembly can include a multiple pole magnet structure, and first and second pole piece assemblies can be provided on opposite first and second sides of the multiple pole magnet structure. In an example, each pole piece assembly defines an airgap over a polarity transition region on a respective side of the magnet structure. First and second voice coils can be provided in respective ones of the airgaps, wherein each of the voice coils is coupled to a respective diaphragm assembly, and at least one acoustic tuning port can be configured to provide a damped acoustic communication path between first and opposite second sides of each diaphragm assembly.

Abstract: Devices, methods and systems for removing unwanted tissue from within a patient's vasculature system are provided. Specifically, a laser ablation catheter having a tip with an open, arched-shaped cross section is described. The cross section of the tip enhances the catheter's ability to ablate, separate, and/or dilate the various layers within a patient's vasculature, thereby facilitating the removal undesirable lesions and fibrous tissue within a patient's vasculature.

Abstract: Certain embodiments are directed to device that use a Spectrum Modulated Frequency controlled LED source that strongly attracts a selected target insect or insect population to a trapping and/or killing system to facilitate the capture or disposal of selected genus of flying insects while limiting the attraction of other flying insects.

Abstract: A dual-diaphragm loudspeaker driver assembly can include a multiple pole magnet structure, and first and second pole piece assemblies can be provided on opposite first and second sides of the multiple pole magnet structure. In an example, each pole piece assembly defines an airgap over a polarity transition region on a respective side of the magnet structure. First and second voice coils can be provided in respective ones of the airgaps, wherein each of the voice coils is coupled to a respective diaphragm assembly, and at least one acoustic tuning port can be configured to provide a damped acoustic communication path between first and opposite second sides of each diaphragm assembly.

Abstract: A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mes