Abstract: An intelligent router for performing functions such as data aggregation from multiple sources, data mining, business intelligence analysis, exploratory data analysis, confirmatory data analysis, predictive data analysis, text analytics, and routing of the results to the appropriate recipient(s) at the appropriate time. The router may comprise an authorization/access manager, a business rules management system, routing engine, data aggregator, community data analytics engine.

Abstract: Systems and methods are provided for analyzing a series of images. A contour initializer establishes a plurality of initial contours from respective images within the series of images. A model initializer interconnects the plurality of initial contours into a surface model. A model refiner refines the plurality of initial contours by manipulating the surface model.

Abstract: An automated method and system for autocontouring organs and other anatomical structures in CT and other medical images employs one or more contouring techniques, depending on the particular organs or structures to be contoured. In a preferred embodiment, an edge-based technique is employed to contour one or more organs. A multiple hypothesis testing technique can be employed to improve the accuracy of the resulting contour. Independent algorithms can be employed for contouring multiple organ in a given region, such as the male pelvic region. An integration algorithm can be employed to combine the results of the independent algorithms to improve accuracy further.

Abstract: A laser catheter is disclosed wherein optical fibers carrying laser light are mounted in a catheter for insertion into an artery to provide controlled delivery of a laser beam for percutaneous intravascular laser treatment of atherosclerotic disease. A transparent protective shield is provided at the distal end of the catheter for mechanically diplacing intravascular blood and protecting the fibers from the intravascular contents, as well as protecting the patient in the event of failure of the fiber optics. Multiple optical fibers allow the selection of tissue that is to be removed. A computer controlled system automatically aligns fibers with the laser and controls exposure time. Spectroscopic diagnostics determine what tissue is to be removed.

Abstract: A system and method for automatically staging regional lymph nodes under the TNM classification system using textural analyses of endoscopic ultrasound images. N stage for a lymph node is determined by analyzing the organization of the texture of a region corresponding to the node on a digitized ultrasound image. Specifically, Haralick's difference entropy and correlation textural features are calculated and compared to predetermined reference values to predict whether the lymph node is benign or malignant. Also, the cross-sectional area of the node is determined and used to make an N staging determination. An application of the present invention is staging of esophageal lymph nodes in the diagnosis and treatment of esophageal carcinoma using endoscopic ultrasound images.

Abstract: A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.

Abstract: A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.