Patents by Inventor Robert M. Dedinsky

Robert M. Dedinsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production and purification of IL-29
    Patent number: 8759027
    Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: June 24, 2014
    Assignee: ZymoGenetics, Inc.
    Inventors: Bruce L. Zamost, Geoffrey F. Lee, Robert M. Dedinsky
  • PRODUCTION AND PURIFICATION OF IL-29
    Publication number: 20120271037
    Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Application
    Filed: June 5, 2012
    Publication date: October 25, 2012
    Inventors: Bruce L. Zamost, Robert M. Dedinsky
  • Production and purification of IL-29
    Patent number: 8211670
    Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: July 3, 2012
    Assignee: ZymoGenetics, Inc.
    Inventors: Bruce L. Zamost, Robert M. Dedinsky
  • PRODUCTION AND PURIFICATION OF IL-29
    Publication number: 20120015403
    Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Application
    Filed: May 24, 2011
    Publication date: January 19, 2012
    Inventors: Bruce L. Zamost, Robert M. Dedinsky
  • Production and purification of IL-29
    Patent number: 7968315
    Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: June 28, 2011
    Assignee: ZymoGenetics, Inc.
    Inventors: Bruce L. Zamost, Robert M. Dedinsky
  • PRODUCTION AND PURIFICATION OF IL-29
    Publication number: 20100222552
    Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Application
    Filed: February 5, 2010
    Publication date: September 2, 2010
    Applicant: ZymoGenetics, LLC
    Inventors: Bruce L. Zamost, Robert M. Dedinsky
  • Production and purification of IL-29
    Patent number: 7759092
    Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Grant
    Filed: August 7, 2009
    Date of Patent: July 20, 2010
    Assignee: ZymoGenetics, LLC
    Inventors: Bruce L. Zamost, Robert M. Dedinsky
  • PRODUCTION AND PURIFICATION OF IL-29
    Publication number: 20100003722
    Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Application
    Filed: August 7, 2009
    Publication date: January 7, 2010
    Applicant: ZymoGenetics, LLC
    Inventors: Bruce L. Zamost, Geoffrey F. Lee, Robert M. Dedinsky
  • PRODUCTION AND PURIFICATION OF IL-29
    Publication number: 20080096252
    Abstract: The expression vectors and methods using an E. Coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
    Type: Application
    Filed: October 4, 2006
    Publication date: April 24, 2008
    Inventors: Bruce L. Zamost, Geoffrey F. Lee, Robert M. Dedinsky