Patents by Inventor Robert M. Iannucci

Robert M. Iannucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metabolites of tricyclic amides useful for inhibition of G-protein function and methods of treatment of proliferative diseases
    Patent number: 7271174
    Abstract: The present invention relates to metabolites of tricyclic amides, and structurally related compounds, represented by the structural formula (I): and pharmaceutically acceptable isomers, salts, solvates or esters of the compound of formula (I), wherein: R1 is selected from the group consisting of H and ?O; R2-R5 can be the same or different, each being independently selected from the group consisting of H, —OH, halide, —NH2 and ?O; and, the combination solid-dashed lines independently represent either single bonds or double bonds, wherein the number of combination solid-dashed lines that are double bonds is not greater than 2, and when, the double bonds are not adjacent, and when 0, one of R1-R5 is not H. Also disclosed are methods of treatment of proliferative diseases and methods for inhibiting the abnormal growth of cells, and for inhibiting farnesyl protein transferase using the novel compounds.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: September 18, 2007
    Assignee: Schering Corporation
    Inventors: Swapan K. Chowdhury, Anima Ghosal, Robert M. Iannucci, Wenqing Feng, Tze-Ming Chan, Shmuel Zbaida, Kevin B. Alton, Ronald J. Doll, Keith P. Minor
  • Substituted 2-azetidinones useful as hypocholesterolemic agents
    Patent number: 6982251
    Abstract: Hypocholesterolemic substituted 2-azetidinone compounds of the formula: are disclosed, as well as a methods of lowering cholesterol by administering said compounds, pharmaceutical compositions containing them, and the combination of a substituted 2-azetidinone cholesterol-lowering agent and a cholesterol biosynthesis inhibitor for the treatment and prevention of atherosclerosis.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: January 3, 2006
    Assignee: Schering Corporation
    Inventors: Anima Ghosal, Shmuel Zbaida, Swapan K. Chowdhury, Robert M. Iannucci, Wenqing Feng, Kevin B. Alton, James E. Patrick, Harry R. Davis
  • Metabolites of tricyclic amides useful for inhibition of G-protein function and methods of treatment of proliferative diseases
    Publication number: 20040266810
    Abstract: The present invention relates to metabolites of tricyclic amides, and structurally related compounds, represented by the structural formula (I): 1
    Type: Application
    Filed: June 23, 2004
    Publication date: December 30, 2004
    Applicant: Schering Corporation
    Inventors: Swapan K. Chowdhury, Anima Ghosal, Robert M. Iannucci, Wenqing Feng, Tze-Ming Chan, Shmuel Zbaida, Kevin B. Alton, Ronald J. Doll, Keith P. Minor
  • Substituted 2-azetidinones useful as hypocholesterolemic agents
    Publication number: 20030105028
    Abstract: Hypocholesterolemic substituted 2-azetidinone compounds of the formula: 1
    Type: Application
    Filed: June 11, 2002
    Publication date: June 5, 2003
    Applicant: Schering Corporation
    Inventors: Anima Ghosal, Shmuel Zbaida, Swapan K. Chowdhury, Robert M. Iannucci, Wenqing Feng, Kevin B. Alton, James E. Patrick, Harry R. Davis
  • Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
    Publication number: 20020137690
    Abstract: please check closely-very confusing Hypocholesterolemic sugar-substituted 2-azetidinone compounds of the formula: 1
    Type: Application
    Filed: December 17, 2001
    Publication date: September 26, 2002
    Applicant: Schering Corporation
    Inventors: Anima Ghosal, Shmuel Zbaida, Swapan K. Chowdhury, Robert M. Iannucci, Wenqing Feng, Kevin B. Alton, James E. Patrick, Harry R. Davis