Abstract: Oral dosage forms of metaxalone having improved bioavailability in the fed and fasted states, including dosage forms that employ a reduced dose based on such improved bioavailability.

Abstract: Oral dosage forms of metaxalone having improved bioavailability in the fed and fasted states, including dosage forms that employ a reduced dose based on such improved bioavailability.

Abstract: Oral dosage forms of metaxalone having improved bioavailability in the fed and fasted states, including dosage forms that employ a reduced dose based on such improved bioavailability.

Abstract: Oral dosage forms of metaxalone having improved bioavailability in the fed and fasted states, including dosage forms that employ a reduced dose based on such improved bioavailability.

Abstract: Oral dosage forms of metaxalone having improved bioavailability in the fed and fasted states, including dosage forms that employ a reduced dose based on such improved bioavailability.

Abstract: Methods of treating autoimmune microvascular conditions using diosmin or diosmetin are described, particularly the treatment of digital ulcers in systemic sclerosis.

Abstract: Oral dosage forms of metaxalone having improved bioavailability in the fed and fasted states, including dosage forms that employ a reduced dose based on such improved bioavailability.

Abstract: Devices, systems and methods are provided for the targeted treatment of movement disorders. Typically, the systems and devices are used to stimulate one or more dorsal root ganglia while minimizing or excluding undesired stimulation of other tissues, such as surrounding or nearby tissues, ventral root and portions of the anatomy associated with body regions which are not targeted for treatment. The dorsal root ganglia are utilized in particular due to their specialized role in movement. It is in these areas that sensory fibers are isolated from motor fibers. Sensory fibers are involved in a variety of reflexes that are involved in movement control, and these reflexes can be utilized in the treatment of various movement disorders. Thus, by stimulating sensory fibers in these areas, fundamental reflexes can be affected to lessen the symptoms of movement disorders.

Abstract: Devices, systems and methods are provided for the targeted treatment of movement disorders. Typically, the systems and devices are used to stimulate one or more dorsal root ganglia while minimizing or excluding undesired stimulation of other tissues, such as surrounding or nearby tissues, ventral root and portions of the anatomy associated with body regions which are not targeted for treatment. The dorsal root ganglia are utilized in particular due to their specialized role in movement. It is in these areas that sensory fibers are isolated from motor fibers. Sensory fibers are involved in a variety of reflexes that are involved in movement control, and these reflexes can be utilized in the treatment of various movement disorders. Thus, by stimulating sensory fibers in these areas, fundamental reflexes can be affected to lessen the symptoms of movement disorders.

Abstract: A device and associated method transfer a person having a handicap from one location to another, such as into or out of a wheelchair, bed, or bathtub. A wheeled base provides mobility to the device. A post and lifter arm support the patient during the transfer. The post is connected to a stabilization arm, which temporarily connects using a stabilization interface to a stabilization bracket. The stabilization bracket is typically attached rather permanently to a wall, ceiling, or other structural feature that provides substantial stability to the system. In various embodiments, the lifter arm may be actuated by hydraulics, the stabilization arm may be extendable, and a pair of extra wheels on the mobility base are adjustable horizontally (e.g., along one hedge of the base frame) or vertically (down to decrease the load on the casters, or up to allow the lifter to be “crabbed” sideways in confined spaces).

Abstract: Wheelchairs in various embodiments include a variable-position drive system that can automatically move the drive wheels fore and aft through an approximately 41 cm range. Such a system provides all the benefits of front-, mid-, and rear-wheel drive configurations in a single wheelchair, for example, to adjust the drive wheels toward the rear for stability and speed outdoors and toward the center for maneuverability indoors. The performance-optimal placement of drive wheels often depends on the physical environment (e.g., terrain), on the combined center of mass of the wheelchair and user, and on the user's cognitive functioning, trunk stability, and driving skills. One disclosed embodiment includes a pair of mid-position drive wheels that can automatically be repositioned forward or backward to accommodate changes in terrain and center of mass, which will improve the power wheelchair's stability and maneuverability and, consequently, safety and ease of use in a wider range of scenarios.

Abstract: Embodiments of the present disclosure include adjustable wheel assemblies for patient lifts. Actuation of a wheel assembly results in the wheel exerting an increased force on the surface supporting the patient lift, which may decrease the pressure of the remaining patient lift wheels on the support surface. Alternate embodiments include one or more adjustable wheel assemblies in a kit for attachment to a patient lift. A user input component may also be included to provide a single device a user can use to simultaneously actuate the wheel assemblies. Alternate embodiments utilize wedges, hinges, cams, and/or threaded members to increase the force exerted by the wheel on the support surface.

Abstract: Devices, systems and methods are provided for the targeted treatment of movement disorders. Typically, the systems and devices are used to stimulate one or more dorsal root ganglia while minimizing or excluding undesired stimulation of other tissues, such as surrounding or nearby tissues, ventral root and portions of the anatomy associated with body regions which are not targeted for treatment. The dorsal root ganglia are utilized in particular due to their specialized role in movement. It is in these areas that sensory fibers are isolated from motor fibers. Sensory fibers are involved in a variety of reflexes that are involved in movement control, and these reflexes can be utilized in the treatment of various movement disorders. Thus, by stimulating sensory fibers in these areas, fundamental reflexes can be affected to lessen the symptoms of movement disorders.

Abstract: Wheelchairs in various embodiments include a variable-position drive system that can automatically move the drive wheels fore and aft through an approximately 41 cm range. Such a system provides all the benefits of front-, mid-, and rear-wheel drive configurations in a single wheelchair, for example, to adjust the drive wheels toward the rear for stability and speed outdoors and toward the center for maneuverability indoors. The performance-optimal placement of drive wheels often depends on the physical environment (e.g., terrain), on the combined center of mass of the wheelchair and user, and on the user's cognitive functioning, trunk stability, and driving skills. One disclosed embodiment includes a pair of mid-position drive wheels that can automatically be repositioned forward or backward to accommodate changes in terrain and center of mass, which will improve the power wheelchair's stability and maneuverability and, consequently, safety and ease of use in a wider range of scenarios.

Abstract: A device and associated method transfer a person having a handicap from one location to another, such as into or out of a wheelchair, bed, or bathtub. A wheeled base provides mobility to the device. A post and lifter arm support the patient during the transfer. The post is connected to a stabilization arm, which temporarily connects using a stabilization interface to a stabilization bracket. The stabilization bracket is typically attached rather permanently to a wall, ceiling, or other structural feature that provides substantial stability to the system. In various embodiments, the lifter arm may be actuated by hydraulics, the stabilization arm may be extendable, and a pair of extra wheels on the mobility base are adjustable horizontally (e.g., along one hedge of the base frame) or vertically (down to decrease the load on the casters, or up to allow the lifter to be “crabbed” sideways in confined spaces).

Abstract: An improvement is disclosed for a flare seal system of the type which includes a flare seal drum containing a body of liquid at a predetermined level and a waste gas inlet conduit extending vertically into the liquid body and having an opening beneath the liquid level, whereby gases discharging from the inlet conduit pass through the liquid body before discharging from the drum to a flare stack. The improvement enables the reduction of gas pulsing from the seal drum, and includes flap valve means pivotally mounted at the wall of the inlet conduit. The flap valve is openable at a point beneath the liquid level, and includes means to bias the valve to a closed position. The inlet gas flow pressure acts against the bias to open the valve, to enable gas flow into the liquid and thence to the flare stack.

Abstract: A training apparatus for training persons to assemble sucker rods to be placed in an oil well includes a frame. A first sucker rod portion is fixedly attached to and extends upwardly from the frame. A second sucker rod portion has an upper end connected to a resiliently extendable coil spring which in turn has its upper end connected to a swivel attached to the frame. The second sucker rod portion is resiliently and rotatably suspended above the first sucker rod portion. The resiliently extendable coil spring is so constructed that it may be extended by downward force so as to engage the first and second sucker rods through a threaded female coupling. This simulates the conditions present in the oil field when the sucker rods are being assembled and permits persons to practice the assembly and disassembly of sucker rods.