Abstract: An apparatus for the introduction or removal of fluid based material from a body of a patient by a clinician. The apparatus comprises a mechanism for connecting into a blood vessel of the patient's blood vessel to continuously introduce fluid based material into or remove the fluid based material from the patient's body. The connecting mechanism is fluidically sealed and self-sealing such that fluid based material cannot escape therefrom and contact the clinician at all times during installation and operation of the apparatus. The apparatus is also comprised of a device for controlling whether the fluid based material is introduced into or removed from the blood vessel while the connecting means is in contact with the blood vessel without the escape of the fluid based material therefrom. The controlling device is in fluidic communication with the connecting mechanism.